Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Samit Joshi"'
Autor:
Aidan McGraw, Grace Hillmer, Stefania M. Medehincu, Yuta Hikichi, Sophia Gagliardi, Kedhar Narayan, Hasset Tibebe, Dacia Marquez, Lilia Mei Bose, Adleigh Keating, Coco Izumi, Kevin Peese, Samit Joshi, Mark Krystal, Kathleen L. DeCicco-Skinner, Eric O. Freed, Luca Sardo, Taisuke Izumi
Publikováno v:
Viruses, Vol 16, Iss 9, p 1423 (2024)
HIV-1 virion maturation is an essential step in the viral replication cycle to produce infectious virus particles. Gag and Gag-Pol polyproteins are assembled at the plasma membrane of the virus-producer cells and bud from it to the extracellular comp
Externí odkaz:
https://doaj.org/article/80d24a174b6e4afea42006719a85adfb
Autor:
Ying Zhang, Mark Bush, Parto Yazdani, Joyce Zhan, Bo Wen, Veronica Bainbridge, Brian R. Wynne, Samit Joshi, Max Lataillade
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 6, Pp n/a-n/a (2023)
Abstract GSK3640254 (GSK'254) is a novel HIV‐1 maturation inhibitor with pharmacokinetics supporting once‐daily (QD) therapy for HIV‐1 treatment. This thorough QT/corrected QT (QTc) study evaluated the effect of GSK'254 on cardiac repolarizatio
Externí odkaz:
https://doaj.org/article/5191d91a05ac43c2a70b1bf6d821069a
Autor:
Ira Dicker, Sharon Zhang, Neelanjana Ray, Brett R Beno, Alicia Regueiro-Ren, Samit Joshi, Mark Cockett, Mark Krystal, Max Lataillade
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224076 (2019)
GSK3532795 (formerly BMS955176) is a second-generation maturation inhibitor (MI) that progressed through a Phase 2b study for treatment of HIV-1 infection. Resistance development to GSK3532795 was evaluated through in vitro methods and was correlated
Externí odkaz:
https://doaj.org/article/3b995319e0514af1ae5adab6ab9b72a9
Autor:
Ying Zhang, Mark Johnson, Samit Joshi, Parto Yazdani, Joyce Zhan, Bo Wen, Veronica Bainbridge, Martin Gartland, Max Lataillade
Publikováno v:
British Journal of Clinical Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28256b7ed1508521a2d08ce97dc95b87
https://doi.org/10.1111/bcp.15699
https://doi.org/10.1111/bcp.15699
Akademický článek
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