Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Samirah Perally"'
1
Akademický článek
Tsetse salivary glycoproteins are modified with paucimannosidic N-glycans, are recognised by C-type lectins and bind to trypanosomes.
Autor: Radoslaw P Kozak, Karina Mondragon-Shem, Christopher Williams, Clair Rose, Samirah Perally, Guy Caljon, Jan Van Den Abbeele, Katherine Wongtrakul-Kish, Richard A Gardner, Daniel Spencer, Michael J Lehane, Álvaro Acosta-Serrano
Publikováno v: PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0009071 (2021)
African sleeping sickness is caused by Trypanosoma brucei, a parasite transmitted by the bite of a tsetse fly. Trypanosome infection induces a severe transcriptional downregulation of tsetse genes encoding for salivary proteins, which reduces its ant
Externí odkaz: https://doaj.org/article/480054e28b21411f9d3a04c5a6f10ac0
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2
Akademický článek
Proteomic profiling and protein identification by MALDI-TOF mass spectrometry in unsequenced parasitic nematodes.
Autor: Paul Millares, E James Lacourse, Samirah Perally, Deborah A Ward, Mark C Prescott, Jane E Hodgkinson, Peter M Brophy, Huw H Rees
Publikováno v: PLoS ONE, Vol 7, Iss 3, p e33590 (2012)
Lack of genomic sequence data and the relatively high cost of tandem mass spectrometry have hampered proteomic investigations into helminths, such as resolving the mechanism underpinning globally reported anthelmintic resistance. Whilst detailed mech
Externí odkaz: https://doaj.org/article/af73e89450fb40c5b95343c09918b299
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3
Akademický článek
The Sigma class glutathione transferase from the liver fluke Fasciola hepatica.
Autor: E James LaCourse, Samirah Perally, Russell M Morphew, Joseph V Moxon, Mark Prescott, David J Dowling, Sandra M O'Neill, Anja Kipar, Udo Hetzel, Elizabeth Hoey, Rafael Zafra, Leandro Buffoni, José Pérez Arévalo, Peter M Brophy
Publikováno v: PLoS Neglected Tropical Diseases, Vol 6, Iss 5, p e1666 (2012)
Liver fluke infection of livestock causes economic losses of over US$ 3 billion worldwide per annum. The disease is increasing in livestock worldwide and is a re-emerging human disease. There are currently no commercial vaccines, and only one drug wi
Externí odkaz: https://doaj.org/article/fcf680e0195140baad18ca2e4a50c4d6
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4
Akademický článek
Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses.
Autor: Jennifer M Fitzpatrick, Emily Peak, Samirah Perally, Iain W Chalmers, John Barrett, Timothy P Yoshino, Alasdair C Ivens, Karl F Hoffmann
Publikováno v: PLoS Neglected Tropical Diseases, Vol 3, Iss 11, p e543 (2009)
Novel methods to identify anthelmintic drug and vaccine targets are urgently needed, especially for those parasite species currently being controlled by singular, often limited strategies. A clearer understanding of the transcriptional components und
Externí odkaz: https://doaj.org/article/a5ab8a53c17540caaf325d8da17762f9
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5
Tsetse salivary glycoproteins are modified with paucimannosidic N-glycans, are recognised by C-type lectins and bind to trypanosomes
Autor: Jan Van Den Abbeele, Katherine Wongtrakul-Kish, Michael J. Lehane, Samirah Perally, Daniel Spencer, Alvaro Acosta-Serrano, Karina Mondragon-Shem, Christopher T Williams, Radoslaw P. Kozak, Richard A. Gardner, Guy Caljon, Clair Rose
Publikováno v: PLoS Neglected Tropical Diseases
PLoS neglected tropical diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0009071 (2021)
African sleeping sickness is caused by Trypanosoma brucei, a parasite transmitted by the bite of a tsetse fly. Trypanosome infection induces a severe transcriptional downregulation of tsetse genes encoding for salivary proteins, which reduces its ant
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9eaa274e6569f2bb109dc0ca57001d
http://europepmc.org/articles/PMC7880456
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6
Schistosoma mansoni venom allergen-like protein 6 (SmVAL6) maintains tegumental barrier function
Autor: Karl F. Hoffmann, Dylan Phillips, Josephine Forde-Thomas, Kathrin K. Geyer, Benjamin J. Hulme, James J. Collins, Leonardo P. Farias, Daniel R. Maskell, Priscila S.G. Farani, Samirah Perally, Iain W. Chalmers, Narcis Fernandez-Fuentes
Publikováno v: International Journal for Parasitology
Graphical abstract
Highlights • Smval6 is expressed in oral/ventral suckers, oesophageal gland and mesenchymal cells of Schistosoma mansoni. • Smval6 knockdown increases surface membrane permeability. • SmVAL6 interacts with Sm14 and DLC p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fa5abda5a5ff176e523336da04dca6
https://pubmed.ncbi.nlm.nih.gov/33253697
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8
Schistosoma mansoni venom allergen-like proteins: phylogenetic relationships, stage-specific transcription and tissue localization as predictors of immunological cross-reactivity
Autor: Martha Brown, Leonardo P. Farias, Henrique K. Rofatto, Cornelis H. Hokke, Luciana C. C. Leite, Mariana I. Khouri, Samirah Perally, Mayra M.F. Barbosa, Colin J. Jackson, Paul J. Hensbergen, Iain W. Chalmers, Karl F. Hoffmann
Publikováno v: International Journal for Parasitology, 49(8), 593-599
International Journal for Parasitology
Graphical abstract
Highlights • The Schistosoma mansoni venom allergen-like (SmVAL) family relationships were investigated. • Transcription patterns of SmVALs associate with phylogenetic relationships. • There was clear antibody cross-reac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9aeb52ae3384756238477e833cd16c7
https://hdl.handle.net/1887/121373
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9
Characterization of a novel glycosylated glutathione transferase of
Autor: Clair, Rose, Giorgio, Praulins, Stuart D, Armstrong, Aitor, Casas-Sanchez, Jem, Davis, Gemma, Molyneux, Cristina, Yunta, Zenaida, Stead, Mark, Prescott, Samirah, Perally, Anne, Rutter, Benjamin L, Makepeace, E James, La Course, Alvaro, Acosta-Serrano
Publikováno v: Parasitology
Filarial nematodes possess glutathione transferases (GSTs), ubiquitous enzymes with the potential to detoxify xenobiotic and endogenous substrates, and modulate the host immune system, which may aid worm infection establishment, maintenance and survi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d0310616f54c794c7ec6c51191e27a59
https://pubmed.ncbi.nlm.nih.gov/31190665
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