Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Samira Yazdi"'
Autor:
Irene Hiniesto-Iñigo, Laura M. Castro-Gonzalez, Valentina Corradi, Mark A. Skarsfeldt, Samira Yazdi, Siri Lundholm, Johan Nikesjö, Sergei Yu Noskov, Bo Hjorth Bentzen, D. Peter Tieleman, Sara I. Liin
Publikováno v:
EBioMedicine, Vol 89, Iss , Pp 104459- (2023)
Summary: Background: Genotype-positive patients who suffer from the cardiac channelopathy Long QT Syndrome (LQTS) may display a spectrum of clinical phenotypes, with often unknown causes. Therefore, there is a need to identify factors influencing dis
Externí odkaz:
https://doaj.org/article/68cc94b6c4f549b4b603e7aeba51442e
Publikováno v:
Cell Reports, Vol 24, Iss 11, Pp 2908-2918 (2018)
Summary: Polyunsaturated fatty acid (PUFA) analogs represent a new class of potential anti-arrhythmic KV7.1 and KV7.1+KCNE1 channel activators. In this study, we describe dual independent activating effects of negatively charged PUFA analogs on KV7.1
Externí odkaz:
https://doaj.org/article/1aad31143aca4177bd176e648363e273
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 1, p e1004704 (2016)
Voltage-gated potassium (KV) channels are membrane proteins that respond to changes in membrane potential by enabling K+ ion flux across the membrane. Polyunsaturated fatty acids (PUFAs) induce channel opening by modulating the voltage-sensitivity, w
Externí odkaz:
https://doaj.org/article/584918b31ce0457ab4cbe3554b4d9333
Publikováno v:
Journal of General Physiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::2cf7aa82f27add32fc8d9503f9847ea0
Autor:
Arina Gromova, Malin Silverå Ejneby, Argel Estrada-Mondragón, Nina E. Ottosson, Samira Yazdi, Stina Borg, Fredrik Elinder, Lucie Delemotte, Panagiotis Apostolakis
Voltage-gated potassium (KV) channels can be opened by negatively charged resin acids and their derivatives. These resin acids have been proposed to attract the positively charged voltage-sensor helix (S4) toward the extracellular side of the membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eab08cc648615e0a0ebedfa946cf4908
https://doi.org/10.1101/2020.06.11.146548
https://doi.org/10.1101/2020.06.11.146548
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 85:17-29
Activation of the transcription factor NF-κB requires degradation of its physiological inhibitor IκBα in order to allow nuclear translocation of NF-kB. NF-κB activity links inflammation and carcinogenesis and makes its signaling pathway an import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d21c5e3826d97d2ba9d613df8a690ae
https://doi.org/10.1002/prot.25181
https://doi.org/10.1002/prot.25181
Autor:
Johan E. Larsson, Samira Yazdi, Peter Tieleman, Williams E. Miranda, Valentina Corradi, Sergei Y. Noskov, Peter Larsson, Sara I. Liin
Publikováno v:
Biophysical Journal. 118:168a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::402772aac5aa77dc2cb53303d5c57e2a
https://doi.org/10.1016/j.bpj.2019.11.1032
https://doi.org/10.1016/j.bpj.2019.11.1032
Publikováno v:
Journal of Molecular Graphics and Modelling
Nuclear factor-κB (NF-κB) transcription factors represent a conserved family of proteins that regulate not only immune cells, but also heart cells, glial cells and neurons, playing a fundamental role in various cellular processes. Due to its dysreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c9d37c82bf6099e91ba63cf863b4af
https://pubmed.ncbi.nlm.nih.gov/30415122
https://pubmed.ncbi.nlm.nih.gov/30415122
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 1, p e1004704 (2016)
PLoS Computational Biology
PLoS Computational Biology
Voltage-gated potassium (KV) channels are membrane proteins that respond to changes in membrane potential by enabling K+ ion flux across the membrane. Polyunsaturated fatty acids (PUFAs) induce channel opening by modulating the voltage-sensitivity, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ea8b9408e22c9748a79efc33719c43
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-125693
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-125693
Autor:
Samira Yazdi, Peter Konradsson, Nina E. Ottosson, Xiongyu Wu, Fredrik Elinder, Erik Lindahl, Malin Silverå Ejneby
Publikováno v:
Biophysical Journal. 112:40a
The naturally occurring resin acid dehydroabietic acid (DHAA) opens a voltage-gated K channel by shifting the voltage dependence of the channel activation to more negative voltages. We synthesized 140 DHAA-derivatives and found that subtle alteration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac4986e55989a63f50202940e8c6a595
https://doi.org/10.1016/j.bpj.2016.11.253
https://doi.org/10.1016/j.bpj.2016.11.253