Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Samira M. Azarin"'
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Energy landscapes can provide intuitive depictions of population heterogeneity and dynamics. However, it is unclear whether individual cell behavior, hypothesized to be determined by initial position and noise, is faithfully recapitulated. U
Externí odkaz:
https://doaj.org/article/dbd72642ec304b8a925f90879db4a4ef
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract A limited number of accessible and representative models of human trophoblast cells currently exist for the study of placentation. Current stem cell models involve either a transition through a naïve stem cell state or precise dynamic contr
Externí odkaz:
https://doaj.org/article/8939c68ec69b4d698b7275fdae324fdf
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Site-specific recombination (SSR) is an important tool in synthetic biology, but its applications are limited by the inability to predictably tune SSR reaction rates. Here, using quantitative high-throughput experiments and machine learning, the auth
Externí odkaz:
https://doaj.org/article/7f7889d4d2ad476dacac02e6588e024f
Autor:
Brandon J. Burbach, Stephen D. O’Flanagan, Qi Shao, Katharine M. Young, Joseph R. Slaughter, Meagan R. Rollins, Tami Jo L. Street, Victoria E. Granger, Lalit. K. Beura, Samira M. Azarin, Satish Ramadhyani, Bruce R. Forsyth, John C. Bischof, Yoji Shimizu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Irreversible electroporation (IRE), a soft-tissue ablation technique used for tumour ablation, has been suggested to promote systemic immune responses. Here the authors show that IRE, followed by anti-CTLA-4 blockade, elicits the expansion of tumor a
Externí odkaz:
https://doaj.org/article/ea3da0e70d734be09e22818a11a9695a
Publikováno v:
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-6 (2020)
Abstract In 2012, we provided the first published evidence that human pluripotent stem cells could be differentiated to cells exhibiting markers and phenotypes characteristic of the blood–brain barrier (BBB). In the ensuing years, the initial proto
Externí odkaz:
https://doaj.org/article/5bd5cf4fb6b644e38cfc8e96e66c6cb6
Autor:
Pedram Motallebnejad, Samira M. Azarin
Publikováno v:
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-16 (2020)
Abstract Background In recent years, differentiation of human induced pluripotent stem cells (hiPSCs) into brain-specific microvascular endothelial cells (iBMECs) has frequently been used to model the blood–brain barrier (BBB). However, there are l
Externí odkaz:
https://doaj.org/article/907ff7d69c784ea1a15a3ca36c7c2dbb
A facile in vitro platform to study cancer cell dormancy under hypoxic microenvironments using CoCl2
Publikováno v:
Journal of Biological Engineering, Vol 12, Iss 1, Pp 1-15 (2018)
Abstract Background While hypoxia has been well-studied in various tumor microenvironments, its role in cancer cell dormancy is poorly understood, in part due to a lack of well-established in vitro and in vivo models. Hypoxic conditions under convent
Externí odkaz:
https://doaj.org/article/7b07b7d0e4d648dd8e745f474d2358a7
Autor:
Catherine A. A. Lee, Hannah S. Seo, Anibal G. Armien, Frank S. Bates, Jakub Tolar, Samira M. Azarin
Publikováno v:
Fluids and Barriers of the CNS, Vol 15, Iss 1, Pp 1-15 (2018)
Abstract Background X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ABCD1 gene. 40% of X-ALD patients will convert to the deadly childhood cerebral form (ccALD) characterized by increased permeability of the brain endothelium that
Externí odkaz:
https://doaj.org/article/a7a44b92acd24c39ad97941c4eca7c2a
Autor:
Shima Salehi, Sehoya Cotner, Samira M. Azarin, Erin E. Carlson, Michelle Driessen, Vivian E. Ferry, William Harcombe, Suzanne McGaugh, Deena Wassenberg, Azariah Yonas, Cissy J. Ballen
Publikováno v:
Frontiers in Education, Vol 4 (2019)
A persistent “gender penalty” in exam performance disproportionately impacts women in large introductory science courses, where exam grades generally account for the majority of the students' assessment of learning. Previous work in introductory
Externí odkaz:
https://doaj.org/article/65e0442437d04bf49ad3f3645d22c0a1
Publikováno v:
bioRxiv
SummaryEnergy landscapes can provide intuitive depictions of population heterogeneity and dynamics. However, it is unclear whether individual cell behavior, hypothesized to be determined by initial position and noise, is faithfully recapitulated. Usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bc6a303fe4cf0f50612fd1b52b3cc7
https://doi.org/10.1101/2023.05.22.541793
https://doi.org/10.1101/2023.05.22.541793
