Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Samira Kiani"'
Autor:
Shayesteh R. Ferdosi, Radwa Ewaisha, Farzaneh Moghadam, Sri Krishna, Jin G. Park, Mo R. Ebrahimkhani, Samira Kiani, Karen S. Anderson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Possible immunogenicity of the Cas9 protein raises concerns about therapeutic applications. Here the authors identify pre-existing CD8+T-cell immunity in healthy individuals and in response modify Cas9 to remove the immunodominant epitopes.
Externí odkaz:
https://doaj.org/article/7163fcf8bec84bbaa28f45dd3cb383d7
Publikováno v:
Biological Journal of Microorganism, Vol 4, Iss 16, Pp 43-48 (2016)
Introduction: Gram-negative bacteria are the most pathogenic bacteria for marine organisms including ornamental fish. Materials and methods: In the present study Vibrio species isolated from ornamental guppy fish in Kashan, Isfahan, Iran fish ponds
Externí odkaz:
https://doaj.org/article/efde595a838d4d46a04fcad5e8ed4bd4
Autor:
Patrick Guye, Mohammad R. Ebrahimkhani, Nathan Kipniss, Jeremy J. Velazquez, Eldi Schoenfeld, Samira Kiani, Linda G. Griffith, Ron Weiss
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
There has been limited success in generating tissues from human induced pluripotent stem cells (hiPSCs). Here, the authors genetically engineer expression of the transcription factor Gata6 in a single isogenic hiPSC population resulting in complex ti
Externí odkaz:
https://doaj.org/article/9b8be1df7dff49edbe97c27e4110a2e7
Autor:
Ryan Forster, Kunitoshi Chiba, Lorian Schaeffer, Samuel G. Regalado, Christine S. Lai, Qing Gao, Samira Kiani, Henner F. Farin, Hans Clevers, Gregory J. Cost, Andy Chan, Edward J. Rebar, Fyodor D. Urnov, Philip D. Gregory, Lior Pachter, Rudolf Jaenisch, Dirk Hockemeyer
Publikováno v:
Stem Cell Reports, Vol 2, Iss 6, Pp 838-852 (2014)
Genetically engineered human pluripotent stem cells (hPSCs) have been proposed as a source for transplantation therapies and are rapidly becoming valuable tools for human disease modeling. However, many applications are limited due to the lack of rob
Externí odkaz:
https://doaj.org/article/29251974b44c49fb94543dca7d398aa3
Autor:
Joseph C Maggiore, Ryan LeGraw, Aneta Przepiorski, Jeremy Velazquez, Christopher Chaney, Evan Streeter, Anne Silva-Barbosa, Jonathan Franks, Joshua Hislop, Alex Hill, Haojia Wu, Katherine Pfister, Sara E Howden, Simon C Watkins, Melissa Little, Benjamin Humphreys, Alan Watson, Donna B Stolz, Samira Kiani, Alan J Davidson, Thomas J. Carroll, Ondine J. Cleaver, Sunder Sims-Lucas, Mo R Ebrahimkhani, Neil A Hukriede
Vascularization plays a critical role in organ maturation and cell type development. Drug discovery, organ mimicry, and ultimately transplantation in a clinical setting thereby hinges on achieving robust vascularization of in vitro engineered organs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a832bb2fd956b83cba53f6fdf775582
https://doi.org/10.1101/2023.05.30.542848
https://doi.org/10.1101/2023.05.30.542848
Publikováno v:
ACS Synthetic Biology. 11:1782-1789
CRISPR-based gene editing is a powerful tool with great potential for applications in the treatment of many inherited and acquired diseases. The longer that CRISPR gene therapy is maintained within a patient, however, the higher the likelihood that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8939b42dc01a7e59e58766b33861f1
https://doi.org/10.1021/acssynbio.1c00621
https://doi.org/10.1021/acssynbio.1c00621
Autor:
Samira Kiani
Publikováno v:
GEN Biotechnology. 1:494-495
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d6ffc2645a36c46631f5f34a573c406
https://doi.org/10.1089/genbio.2022.29065.ski
https://doi.org/10.1089/genbio.2022.29065.ski
Publikováno v:
Iranian journal of biotechnology. 20(1)
In the current study, the created variation of second-generation mutant (M2) camelina lines in terms of fatty acid profiles and ISSR molecular markers inFor this purpose, while producing the first-generation of mutant plants (M1), 200 M2 seeds with 0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c0ffc0a7943177e972725bef6ff58b5
https://pubmed.ncbi.nlm.nih.gov/35891951
https://pubmed.ncbi.nlm.nih.gov/35891951
Autor:
Ross C. Wilson, Kevin D. Wells, W. Mark Saltzman, Philip J. Santangelo, Guohua Yi, Aravind Asokan, Shengdar Q. Tsai, Nenad Bursac, R. Holland Cheng, Shaoqin Gong, Gang Bao, Jennifer A. Doudna, Venkata S. Sabbisetti, Jarryd M. Campbell, Ryuji Morizane, Charles A. Gersbach, Mary E. Dickinson, Jon D. Hennebold, Kit S. Lam, Zheng-Yi Chen, John T. Hinson, Melinda R. Dwinell, Daniel G. Anderson, William R. Lagor, Qiaobing Xu, Melissa C. Skala, Jennifer A. Lewis, David J. Segal, Samantha Maragh, Guoping Feng, Stephen C. Ekker, Benjamin E. Deverman, Jonathan K. Watts, Alice F. Tarantal, Moriel H. Vandsburger, George A. Truskey, Ionita Ghiran, Marina E. Emborg, Jeff W.M. Bulte, Scot A. Wolfe, James E. Dahlman, Niren Murthy, Paul B. McCray, Erik J. Sontheimer, John C. Tilton, David T. Curiel, Benjamin S. Freedman, Guangping Gao, Mary Shimoyama, Kam W. Leong, Jiangbing Zhou, P. J. Brooks, Samira Kiani, Krystof S. Bankiewicz, Karl J. Clark, Jillian F. Banfield, Jon E. Levine, Krishanu Saha, Todd C. McDevitt, David R. Liu, Randall S. Prather, Daniel F. Carlson, Peter M. Glazer, Elliot L. Chaikof, Jason D. Heaney, Subhojit Roy, John A. Ronald, Stephen A. Murray, Cathleen M. Lutz, Anastasia Khvorova, Wen Xue, Sushmita Roy, Oleg Mirochnitchenko, Danith H. Ly, David M. Gamm
Publikováno v:
Nature
The move from reading to writing the human genome offers new opportunities to improve human health. The United States National Institutes of Health (NIH) Somatic Cell Genome Editing (SCGE) Consortium aims to accelerate the development of safer and mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9d20149cb2c9628c47c5de7bd8b66f
https://doi.org/10.1038/s41586-021-03191-1
https://doi.org/10.1038/s41586-021-03191-1
Publikováno v:
Curr Opin Biomed Eng
As genome editors move into clinical trials, there is a need to establish ex vivo multicellular systems to rapidly assess and predict toxic effects of genome editors in physiologically relevant human models. Advancements in organoid and organs-on-chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c43347b247c65a3a22623277c1b1bc5
https://doi.org/10.1016/j.cobme.2020.100249
https://doi.org/10.1016/j.cobme.2020.100249