Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Samira Khabbazi"'
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Macrophages are abundant in the tumor microenvironment where they adopt a pro-tumor phenotype following alternative polarization induced by paracrine factors from cancer and stromal cells. In contrast, classically activated macrophages have tumoricid
Externí odkaz:
https://doaj.org/article/fc42edca14e4408b9190fcc21fcf9685
Autor:
Samira Khabbazi, Zeyad D. Nassar, Gregory J. Riggins, Wenjun Pu, Nan Xie, Kerrie-Ann McMahon, Marie-Odile Parat, Robert G. Parton, Jonathan M. Harris
Publikováno v:
Journal of Neuro-Oncology. 143:207-220
Glioblastoma (GBM) is the most common primary brain cancer. The average survival time for the majority of patients is approximately 15 months after diagnosis. A major feature of GBM that contributes to its poor prognosis is its high invasiveness. Cav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce5243ea749da427cd6f107f19c5add
https://doi.org/10.1007/s11060-019-03161-8
https://doi.org/10.1007/s11060-019-03161-8
Autor:
Qian Tang, Cory J. Xian, Chiaming Fan, Xue-sen Wen, Mohammadhossein Hassanshahi, Yuwen Su, Jian Fan, Samira Khabbazi, Ke-Ming Chen
Publikováno v:
Journal of Cellular Physiology. 234:16549-16561
Methotrexate (MTX), a widely used antimetabolite in paediatric cancer to treatment, has been widely reported to cause bone loss and bone marrow (BM) microvascular (particularly sinusoids) damage. Investigations must now investigate how MTX-induced bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181a46a570354d282febccff5893f132
https://doi.org/10.1002/jcp.28326
https://doi.org/10.1002/jcp.28326
Autor:
Alireza Hassanshahi, Cory J. Xian, Yaser Peymanfar, Mohammadhossein Hassanshahi, Samira Khabbazi, Yuwen Su
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 392:123-133
Opioids are widely administered to alleviate pain, including chronic pain in advanced cancer patients. Among opioids, morphine is one of the most clinically effective drugs for the palliative management of severe pain. In the last few decades, there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c921c0985544ce048bc4c3cda6e8fa
https://doi.org/10.1007/s00210-019-01613-6
https://doi.org/10.1007/s00210-019-01613-6
Autor:
David Sturgess, Kye Gregory, Marie-Odile Parat, Zeyad D. Nassar, Tharindu Vithanage, Nan Xie, Paul N. Shaw, Samira Khabbazi, Bela Anand-Apte, Peter J. Cabot
Publikováno v:
The FASEB Journal. 31:5208-5216
Opioids modulate the tumor microenvironment with potential functional consequences for tumor growth and metastasis. We evaluated the effects of morphine administration on the circulating proteolytic profile of tumor-free mice. Serum from morphine-tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e4e4754be279791270eddb00f09c1a
https://doi.org/10.1096/fj.201700546r
https://doi.org/10.1096/fj.201700546r
Autor:
Suresh Kumar Veliyath, Girdhar Singh Deora, Jared A. Miles, Samira Khabbazi, Gawain McColl, Marie-Odile Parat, Benjamin P. Ross, Srinivas Kantham, Stephen Chan, Satish N. Dighe
Publikováno v:
ACS Chemical Neuroscience. 8:1901-1912
The biphenyl neolignan honokiol is a neuroprotectant which has been proposed as a treatment for central nervous system disorders such as Alzheimer’s disease (AD). The death of cholinergic neurons in AD is attributed to multiple factors, including a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2692a968a72d2a7c3f697793e91c516
https://doi.org/10.1021/acschemneuro.7b00071
https://doi.org/10.1021/acschemneuro.7b00071
Autor:
De-Wen Yan, Samira Khabbazi, Yuwen Su, Peter R. C. Howe, Cory J. Xian, Chiaming Fan, Mohammadhossein Hassanshahi, Airong Qian, Hou-De Zhou, Ke-Ming Chen, Jufang Wang
Cancer chemotherapy can cause significant damage to the bone marrow (BM) microvascular (sinusoidal) system. Investigations must now address whether and how BM sinusoidal endothelial cells (SECs) can be protected during chemotherapy. Herein we examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3c95d57f709ea18841bdc289ff7854
https://hdl.handle.net/11541.2/135503
https://hdl.handle.net/11541.2/135503
Autor:
Alireza Hassanshahi, Yuwen Su, Zahra Hosseini-Khah, Samira Khabbazi, Yaser Peymanfar, Mohammadhossein Hassanshahi, Cory J. Xian
Critical limb ischemia (CLI) is the advanced stage of peripheral artery disease spectrum and is defined by limb pain or impending limb loss because of compromised blood flow to the affected extremity. Current conventional therapies for CLI include am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be69b43b5e1693a75ce8abe81221e79
https://hdl.handle.net/11541.2/135746
https://hdl.handle.net/11541.2/135746
Autor:
Yuwen Su, Saman Ghalamkari, Samira Khabbazi, Cory J. Xian, Alireza Hassanshahi, Zahra Hosseini-Khah, Yaser Peymanfar, Mohammadhossein Hassanshahi
Publikováno v:
Journal of cellular physiology. 234(6)
Wound healing is a complex but a fine-tuned biological process in which human skin has the ability to regenerate itself following damage. However, in particular conditions such as deep burn or diabetes the process of wound healing is compromised. Des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc476a3b6118d88ad4f44123af3ce9a2
https://pubmed.ncbi.nlm.nih.gov/30515810
https://pubmed.ncbi.nlm.nih.gov/30515810
Publikováno v:
Critical reviews in oncology/hematology. 137
Despite more attention to cell migration from circulation into the bone marrow (BM), particularly homing of haematopoietic stem/progenitor cells, the process and mechanisms of cell mobilisation from the BM into the circulation remain largely underexp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ab824c5863e64838c999fff039c191
https://pubmed.ncbi.nlm.nih.gov/31014515
https://pubmed.ncbi.nlm.nih.gov/31014515