Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Samira G, Ferreira"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Externí odkaz:
https://doaj.org/article/ae4245259f494e46a9dc4f5a85b0a64c
Autor:
Cátia R. Lopes, Joana S. Silva, Joana Santos, Matilde S. Rodrigues, Daniela Madeira, Andreia Oliveira, Ana Moreira-de-Sá, Vanessa S. Lourenço, Francisco Q. Gonçalves, Henrique B. Silva, Ana Patrícia Simões, Anabela P. Rolo, Paula M. Canas, Ângelo R. Tomé, Carlos M. Palmeira, João Pedro Lopes, Rodrigo A. Cunha, Paula Agostinho, Samira G. Ferreira
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 6968 (2023)
Alzheimer’s disease (AD), which predominantly affects women, involves at its onset a metabolic deregulation associated with a synaptic failure. Here, we performed a behavioral, neurophysiological and neurochemical characterization of 9-month-old fe
Externí odkaz:
https://doaj.org/article/74eefc30c039410eb7b8b72a8ce3d869
Autor:
Attila Köfalvi, Estefanía Moreno, Arnau Cordomí, Ning-Sheng Cai, Victor Fernández-Dueñas, Samira G. Ferreira, Ramón Guixà-González, Marta Sánchez-Soto, Hideaki Yano, Verònica Casadó-Anguera, Rodrigo A. Cunha, Ana Maria Sebastião, Francisco Ciruela, Leonardo Pardo, Vicent Casadó, Sergi Ferré
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-21 (2020)
Abstract Background It has been hypothesized that heteromers of adenosine A2A receptors (A2AR) and cannabinoid CB1 receptors (CB1R) localized in glutamatergic nerve terminals mediate the integration of adenosine and endocannabinoid signaling involved
Externí odkaz:
https://doaj.org/article/7b04e035274446de8e3bed6703c6c493
Autor:
Cátia R. Lopes, Andreia Oliveira, Ingride Gaspar, Matilde S. Rodrigues, Joana Santos, Eszter Szabó, Henrique B. Silva, Ângelo R. Tomé, Paula M. Canas, Paula Agostinho, Rui A. Carvalho, Rodrigo A. Cunha, Ana Patrícia Simões, João Pedro Lopes, Samira G. Ferreira
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 106 (2023)
Adenosine receptors mainly control synaptic function, and excessive activation of adenosine receptors may worsen the onset of many neurological disorders. Accordingly, the regular intake of moderate doses of caffeine antagonizes adenosine receptors a
Externí odkaz:
https://doaj.org/article/c1dfbb01209e4e63a8978f837859d8ba
Autor:
Ana Patrícia Simões, Francisco Q. Gonçalves, Daniel Rial, Samira G. Ferreira, João Pedro Lopes, Paula M. Canas, Rodrigo A. Cunha
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12826 (2022)
Adenosine A2A receptors (A2AR) control fear memory and the underlying processes of synaptic plasticity in the amygdala. In other brain regions, A2AR activation is ensured by ATP-derived extracellular adenosine formed by ecto-5′-nucleotidase or CD73
Externí odkaz:
https://doaj.org/article/bf67d92b1f7a47ef9716b399742bc61e
Autor:
Bruno Gonçalves Pinheiro, Diandra Araújo Luz, Sabrina de Carvalho Cartágenes, Luanna de Melo Pereira Fernandes, Sarah Viana Farias, Natália Harumi Correa Kobayashi, Enéas Andrade Fontes-Júnior, Samira G. Ferreira, Rodrigo A. Cunha, Rui Daniel Prediger, Cristiane do Socorro Ferraz Maia
Publikováno v:
Pharmaceuticals, Vol 15, Iss 11, p 1323 (2022)
Binge drinking intake is the most common pattern of ethanol consumption by adolescents, which elicits emotional disturbances, mainly anxiety and depressive symptoms, as well as cognitive alterations. Ethanol exposure may act on the adenosine neuromod
Externí odkaz:
https://doaj.org/article/5e798138d8d04e0fa165320648472a01
Autor:
Liliana Dias, Daniela Pochmann, Cristina Lemos, Henrique B. Silva, Joana I. Real, Francisco Q. Gonçalves, Daniel Rial, Nélio Gonçalves, Ana Patrícia Simões, Samira G. Ferreira, Paula Agostinho, Rodrigo A. Cunha, Angelo R. Tomé
Publikováno v:
ACS Chemical Neuroscience. 14:1299-1309
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64f4301063c748fa6d021ef96fe577a3
https://doi.org/10.1021/acschemneuro.2c00810
https://doi.org/10.1021/acschemneuro.2c00810
Autor:
Matilde S. Rodrigues, Samira G. Ferreira, César Quiroz, Christopher J. Earley, Diego García-Borreguero, Rodrigo A. Cunha, Francisco Ciruela, Attila Köfalvi, Sergi Ferré
Publikováno v:
Molecules, Vol 27, Iss 5, p 1489 (2022)
Brain iron deficiency (BID) constitutes a primary pathophysiological mechanism in restless legs syndrome (RLS). BID in rodents has been widely used as an animal model of RLS, since it recapitulates key neurochemical changes reported in RLS patients a
Externí odkaz:
https://doaj.org/article/84996bcbe2df4dbba35686e4de4c23b3
Autor:
Francisco Q. Gonçalves, João P. Lopes, Henrique B. Silva, Cristina Lemos, António C. Silva, Nélio Gonçalves, Ângelo R. Tomé, Samira G. Ferreira, Paula M. Canas, Daniel Rial, Paula Agostinho, Rodrigo A. Cunha
Publikováno v:
Neurobiology of Disease, Vol 132, Iss , Pp - (2019)
Adenosine A2A receptors (A2AR) overfunction causes synaptic and memory dysfunction in early Alzheimer's disease (AD). In a β-amyloid (Aβ1-42)-based model of early AD, we now unraveled that this involves an increased synaptic release of ATP coupled
Externí odkaz:
https://doaj.org/article/5afe45d9cdb74873aa61a2ff27b5edf9
Autor:
Douglas T. Leffa, Pablo Pandolfo, Nélio Gonçalves, Nuno J. Machado, Carolina M. de Souza, Joana I. Real, António C. Silva, Henrique B. Silva, Attila Köfalvi, Rodrigo A. Cunha, Samira G. Ferreira
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Adenosine A2A receptors (A2ARs) were recently described to control synaptic plasticity and network activity in the prefrontal cortex (PFC). We now probed the role of these PFC A2AR by evaluating the behavioral performance (locomotor activity, anxiety
Externí odkaz:
https://doaj.org/article/7f828bbc6a6b4a82be3384e5d9ff7c7c