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pro vyhledávání: '"Samira Elbai"'
Autor:
Gillian Moore, Stephen P. Finn, Katie E. O’Sullivan, Carmen Blanco-Aparicio, Lauren Brady, Samira Elbai, Siobhan Nicholson, Michael O'Neill, Clara Lightner, Kenneth J. O'Byrne, Kathy Gately, Susan Heavey, Sinead Cuffe, R. Ryan
Publikováno v:
Cancers
Volume 13
Issue 9
Cancers, Vol 13, Iss 2139, p 2139 (2021)
Volume 13
Issue 9
Cancers, Vol 13, Iss 2139, p 2139 (2021)
Simple Summary PIM kinases interact with major oncogenic players, including the PI3K/Akt pathway, and provide an escape mechanism leading to drug resistance. This study examined PIM kinase expression in NSCLC and the potential of PIM1 as a prognostic
Publikováno v:
Molecular Cancer Research. 18:B14-B14
Introduction: The PI3K pathway is often dysregulated in lung cancer, making it an ideal therapeutic target. Pan- and isoform-specific inhibitors of the PI3K pathway are currently being evaluated in clinical trials. However, all patients treated thus