Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Samira Buhrer-Sékula"'
Autor:
Matheus Bernardes Torres Fogaça, Djairo Pastor Saavedra, Leonardo Lopes-Luz, Bergmann Morais Ribeiro, Luciano da Silva Pinto, Tatsuya Nagata, Fabricio Rochedo Conceição, Mariane Martins de Araújo Stefani, Samira Buhrer-Sékula
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e29938- (2024)
Lateral flow immunoassays (LFIA) for antibody detection represent cost-effective and user-friendly tools for serology assessment. This study evaluated a new LFIA prototype developed with a recombinant chimeric antigen from the spike/S and nucleocapsi
Externí odkaz:
https://doaj.org/article/19dfd56d4be64882ab7db64727c04fa8
Autor:
Gerson Oliveira Penna, Maria Araci de Andrade Pontes, Sinésio Talhari, Heitor de Sá Gonçalves, Carolina Talhari, Allen de Souza Pessoa, Valderiza Pedroza, Samira Bührer-Sékula, Mariane Martins de Araujo Stefani, Maria Lucia Fernandes Penna
Publikováno v:
Brazilian Journal of Infectious Diseases, Vol 28, Iss 2, Pp 103745- (2024)
Background: Leprosy is a neglected dermato-neurologic, infectious disease caused by Mycobacterium leprae or M. lepromatosis. Leprosy is treatable and curable by multidrug therapy/MDT, consisting of 12 months rifampicin, dapsone and clofazimine for mu
Externí odkaz:
https://doaj.org/article/5598effc02cd4a16bb449ea8b9360489
Autor:
Rafael Saraiva de Andrade Rodrigues, Eduardo Ferreira José Heise, Luis Felipe Hartmann, Guilherme Eduardo Rocha, Marcia Olandoski, Mariane Martins de Araújo Stefani, Ana Carla Pereira Latini, Cleverson Teixeira Soares, Andrea Belone, Patrícia Sammarco Rosa, Maria Araci de Andrade Pontes, Heitor de Sá Gonçalves, Rossilene Cruz, Maria Lúcia Fernandes Penna, Deborah Ribeiro Carvalho, Vinicius Medeiros Fava, Samira Bührer-Sékula, Gerson Oliveira Penna, Claudia Maria Cabral Moro, Julio Cesar Nievola, Marcelo Távora Mira
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionLeprosy reactions (LR) are severe episodes of intense activation of the host inflammatory response of uncertain etiology, today the leading cause of permanent nerve damage in leprosy patients. Several genetic and non-genetic risk factors
Externí odkaz:
https://doaj.org/article/b26ff41f1e204a50b26f0dc2d27de53e
Autor:
Maria Lucia Fernandes, Penna, Samira, Buhrer-Sékula, Maria Araci De Andrade, Pontes, Rossilene, Cruz, Heitor De Sá, Gonçalves, Gerson Oliveira, Penna
Publikováno v:
Leprosy review. 83(3)
Many believe that the regular treatment for multibacillary (MB) leprosy cases could be shortened. A shorter treatment, allowing for uniform treatment for all cases, makes case classification superfluous and therefore simplifies leprosy control.To eva
Autor:
Rossilene Conceição da Silva Cruz, Samira Bührer-Sékula, Gerson Oliveira Penna, Maria Elisabete Amaral de Moraes, Heitor de Sá Gonçalves, Mariane Martins de Araújo Stefani, Maria Lúcia Fernandes Penna, Maria Araci de Andrade Pontes, Sinésio Talhari
Publikováno v:
Anais Brasileiros de Dermatologia, Vol 93, Iss 3, Pp 377-384 (2018)
Abstract: BACKGROUND: The Clinical Trial for Uniform Multidrug Therapy for Leprosy Patients in Brazil (U-MDT/CT-BR), designed to evaluate the effectiveness of a six-months regimen, assessed the adverse effects caused by the drugs. OBJECTIVE: Describe
Externí odkaz:
https://doaj.org/article/c65892aaa06d4fcbb86ef20da09ae940
Autor:
Andrej Benjak, Charlotte Avanzi, Pushpendra Singh, Chloé Loiseau, Selfu Girma, Philippe Busso, Amanda N. Brum Fontes, Yuji Miyamoto, Masako Namisato, Kidist Bobosha, Claudio G. Salgado, Moisés B. da Silva, Raquel C. Bouth, Marco A. C. Frade, Fred Bernardes Filho, Josafá G. Barreto, José A. C. Nery, Samira Bührer-Sékula, Andréanne Lupien, Abdul R. Al-Samie, Yasin Al-Qubati, Abdul S. Alkubati, Gisela Bretzel, Lucio Vera-Cabrera, Fatoumata Sakho, Christian R. Johnson, Mamoudou Kodio, Abdoulaye Fomba, Samba O. Sow, Moussa Gado, Ousmane Konaté, Mariane M. A. Stefani, Gerson O. Penna, Philip N. Suffys, Euzenir Nunes Sarno, Milton O. Moraes, Patricia S. Rosa, Ida M. F. Dias Baptista, John S. Spencer, Abraham Aseffa, Masanori Matsuoka, Masanori Kai, Stewart T. Cole
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Leprosy is caused by the yet-uncultured pathogen Mycobacterium leprae. Here, Benjak et al. obtain M. leprae genome sequences from DNA extracted from patients' skin biopsies and, by analysing 154 genomes from 25 countries, provide insight into the pat
Externí odkaz:
https://doaj.org/article/d0872b16248e40f0a1f5adae60f93176
Autor:
Rossilene Conceição da Silva Cruz, Samira Bührer-Sékula, Maria Lúcia F. Penna, Gerson Oliveira Penna, Sinésio Talhari
Publikováno v:
Anais Brasileiros de Dermatologia, Vol 92, Iss 6, Pp 761-773 (2017)
Abstract: In this review, the most relevant and current epidemiological data, the main clinical, laboratory and therapeutical aspects of leprosy are presented. Detailed discussion of the main drugs used for leprosy treatment, their most relevant adve
Externí odkaz:
https://doaj.org/article/a5fea9aee2ea4127b2abd5222e83a8ca
Autor:
João Hugo Abdalla Santos, Samira Bührer-Sékula, Gisely Cardoso Melo, Marcelo Cordeiro-Santos, João Paulo Diniz Pimentel, Adriano Gomes-Silva, Allyson Guimarães Costa, Valeria Saraceni, Alda Maria Da-Cruz, Marcus Vinícius Guimarães Lacerda
Publikováno v:
Revista da Sociedade Brasileira de Medicina Tropical, Vol 52 (2019)
Abstract INTRODUCTION: Immunological control of Mycobacterium tuberculosis infection is dependent on the cellular immune response, mediated predominantly by Th1 type CD4+ T cells. Polarization of the immune response to Th2 can inhibit the host immune
Externí odkaz:
https://doaj.org/article/a5e21e7e7d8a48048cfd0cf0ddee4f6c
Autor:
Emerith M. Hungria, Samira Bührer-Sékula, Regiane M. Oliveira, Lúcio C. Aderaldo, Maria Araci A. Pontes, Rossilene Cruz, Heitor S. de Gonçalves, Maria L. F. Penna, Gerson O. Penna, Mariane M. A. Stefani
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Leprosy serology reflects the bacillary load of patients and multidrug therapy (MDT) reduces Mycobacterium leprae-specific antibody titers of multibacillary (MB) patients. The Clinical Trial for Uniform Multidrug Therapy Regimen for Leprosy Patients
Externí odkaz:
https://doaj.org/article/cc188b9118d841d7b01b0ebe4a9fde0a
Autor:
Marlucia da Silva Garrido, Samira Bührer-Sékula, Alexandra Brito de Souza, Rajendranath Ramasawmy, Patrícia de Lima Quincó, Rossicleia Lins Monte, Lucilaide Oliveira Santos, Tomás Maria Perez-Porcuna, Flor Ernestina Martinez-Espínosa, Valéria Saraceni, Marcelo Cordeiro-Santos
Publikováno v:
Revista da Sociedade Brasileira de Medicina Tropical, Vol 48, Iss suppl 1, Pp 63-69 (2015)
Tuberculosis (TB) is one of the infectious diseases that contributes most to the morbidity and mortality of millions of people worldwide. Brazil is one of 22 countries that accounts for 80% of the tuberculosis global burden. The highest incidence rat
Externí odkaz:
https://doaj.org/article/0bce8d6424a74e12b6dc0ddeb2860d96