Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Samira Laouirem"'
A new NRF2 activator for the treatment of human metabolic dysfunction-associated fatty liver disease
Autor:
Adel Hammoutene, Samira Laouirem, Miguel Albuquerque, Nathalie Colnot, Angélique Brzustowski, Dominique Valla, Nicolas Provost, Philippe Delerive, Valérie Paradis
Publikováno v:
JHEP Reports, Vol 5, Iss 10, Pp 100845- (2023)
Background & Aims: Oxidative stress triggers metabolic-associated fatty liver disease (MAFLD) and fibrosis. Previous animal studies demonstrated that the transcription factor nuclear factor (erythroid-derived 2)-like 2 (NRF2), the master regulator of
Externí odkaz:
https://doaj.org/article/797f996f516a4f5ebd96f64fabc15d6d
Autor:
Elia Gigante, Hélène Cazier, Miguel Albuquerque, Samira Laouirem, Aurélie Beaufrère, Valérie Paradis
Publikováno v:
Cancers; Volume 15; Issue 7; Pages: 2143
Combined hepato-cholangiocarcinomas (cHCC-CCA) belong to the spectrum of primary liver carcinomas, which include hepatocellular carcinomas (HCC) and intrahepatic cholangiocarcinomas (iCCA) at both ends of the spectrum. Mainly due to the high intratum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b2b906dd1a29c9ace97792471a04bc
Autor:
Pierre Bedossa, Magda Negrão, Jerome Raffenne, Jérôme Cros, Miguel Godinho Ferreira, Rita Fior, Nicolas Poté, Samira Laouirem, Valérie Paradis, Slimane Ait Si Ali, Miguel Albuquerque
Publikováno v:
Liver International
Liver International, 2020, 40, Epub ahead of print. ⟨10.1111/LIV.14381⟩
Liver International, Wiley-Blackwell, 2020, 40 (4), pp.956-967. ⟨10.1111/liv.14381⟩
Liver International, Wiley-Blackwell, 2020, 40, Epub ahead of print. ⟨10.1111/LIV.14381⟩
Liver International, 2020, 40, Epub ahead of print. ⟨10.1111/LIV.14381⟩
Liver International, Wiley-Blackwell, 2020, 40 (4), pp.956-967. ⟨10.1111/liv.14381⟩
Liver International, Wiley-Blackwell, 2020, 40, Epub ahead of print. ⟨10.1111/LIV.14381⟩
International audience; BACKGROUND & AIMS:Vascular invasion is a major prognostic factor in hepatocellular carcinoma (HCC). We previously identified histone H4 acetylated at lysine 16 (H4K16ac), a histone modification involved in transcription activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e294b1b9bdb0059bfff5011fe1fc0f
https://www.hal.inserm.fr/inserm-02532680
https://www.hal.inserm.fr/inserm-02532680
Autor:
Pierre Bedossa, Thibaut Léger, Valérie Paradis, Jean-Michel Camadro, Denis Mestivier, Theodore Alexandrov, Mouniya Mebarki, Xavier Baudin, Samira Laouirem, Julie Le Faouder
Publikováno v:
The Journal of Pathology. 234:452-463
Cirrhosis is a lesion at risk of hepatocellular carcinoma (HCC). Identifying mechanisms associated with the transition from cirrhosis to HCC and characterizing biomarkers of cirrhosis at high risk of developing into cancer are crucial for improving e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97c77f21522d8d4dbb854b3e1f67975c
https://doi.org/10.1002/path.4398
https://doi.org/10.1002/path.4398
Autor:
Theodore Alexandrov, Thibaut Léger, Pierre Bedossa, Valérie Paradis, Julie Le Faouder, Miguel Albuquerque, Soundes Ben-Harzallah, Samira Laouirem
Publikováno v:
PROTEOMICS. 14:965-972
Cholangiocarcinoma (CC) is the second most common primary malignancy of the liver. Although all CC derive from biliary epithelial cells, two main subtypes, hilar (H), and peripheral (P) CC are described. The objective of the study was to compare, usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32d37def3cdf4e59913c34ad112a4c73
https://doi.org/10.1002/pmic.201300463
https://doi.org/10.1002/pmic.201300463
Autor:
Pierre Bourgoin, Samira Laouirem, Olivier Soubrane, Sandrine Faivre, Miguel Albuquerque, Bernard E. Van Beers, François Cauchy, Mouniya Mebarki, Simon A. Lambert, Benjamin Leporq, Valérie Paradis, Pierre Bedossa
Publikováno v:
Clinical Science
Clinical Science, Portland Press, 2016, 131 (1), pp.27-36. ⟨10.1042/CS20160438⟩
Clinical Science, Portland Press, 2016, 131 (1), pp.27-36. ⟨10.1042/CS20160438⟩
Studies suggest that metformin, widely used for treating Type 2 diabetes, possesses innate antineoplastic properties. For metabolic syndrome patients with hepatocellular carcinoma (HCC), metformin may provide antitumoral effects. We evaluated the imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78934e2c5d8f95bb071c6e47af9986b7
https://pubmed.ncbi.nlm.nih.gov/27803295
https://pubmed.ncbi.nlm.nih.gov/27803295
Autor:
Miguel Albuquerque, Samira Laouirem, Valérie Paradis, O. Soubrane, F. Lagadec, P. Bedossa, Jérôme Cros
Publikováno v:
Journal of Hepatology. 66:S635-S636
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::552a61aa43284e2abaed2e9aab9ee2f5
https://doi.org/10.1016/s0168-8278(17)31722-1
https://doi.org/10.1016/s0168-8278(17)31722-1
Autor:
Eric Raymond, Pierre Bedossa, Pierre-Emmanuel Rautou, Samira Laouirem, Valérie Paradis, François Cauchy, Mouniya Mebarki, Miguel Albuquerque, Olivier Soubrane
Publikováno v:
Gut. 64(9)
Dear Editor, We read with interest the work by Chen et al 1 who reported the decreased risk for developing hepatocellular carcinoma (HCC) in patients treated with metformin in a dose-dependent and time-dependent manner. Indeed, the metabolic syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ee0a42a466dfb2d7331e9bdf5c8330
https://pubmed.ncbi.nlm.nih.gov/22773548
https://pubmed.ncbi.nlm.nih.gov/22773548
Autor:
Samira, Laouirem, Julie, Le Faouder, Theodore, Alexandrov, Denis, Mestivier, Thibaut, Léger, Xavier, Baudin, Mouniya, Mebarki, Valérie, Paradis, Jean-Michel, Camadro, Pierre, Bedossa
Publikováno v:
The Journal of pathology. 234(4)
Cirrhosis is a lesion at risk of hepatocellular carcinoma (HCC). Identifying mechanisms associated with the transition from cirrhosis to HCC and characterizing biomarkers of cirrhosis at high risk of developing into cancer are crucial for improving e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87d8b476a097849106dfafe8b1f6de00
https://pubmed.ncbi.nlm.nih.gov/24979321
https://pubmed.ncbi.nlm.nih.gov/24979321
Autor:
Pierre Bourgoin, Anne Couvelard, Bénédicte Jaïs, Pierre Bedossa, Valérie Paradis, Konstantinos Arapis, Miguel Albuquerque, Philippe Ruszniewski, Vinciane Rebours, Jean-Pierre Marmuse, Maude Le Gall, Samira Laouirem, Alain Sauvanet, Jérôme Cros
Publikováno v:
Gastroenterology. 148:S-928
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::393e36938301916e39a985e109351e72
https://doi.org/10.1016/s0016-5085(15)33156-5
https://doi.org/10.1016/s0016-5085(15)33156-5