Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Samir S El-Dahr"'
Publikováno v:
Molecular and Cellular Pediatrics, Vol 11, Iss 1, Pp 1-15 (2024)
Abstract Background Parental malnutrition, particularly a low-protein diet (LPD), causes oligonephropathy at birth and predisposes offspring to hypertension and chronic kidney disease later in life. The onset of adult kidney disease varies based on g
Externí odkaz:
https://doaj.org/article/441c258f653949be8cae4df4cb8c65e1
Autor:
Fabiola Diniz, Francesca Edgington-Giordano, Nguyen Yen Nhi Ngo, Gal Caspi, Samir S. El-Dahr, Giovane G. Tortelote
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39552- (2024)
Background: Parental nutritional status is crucial in shaping offspring's kidney development. However, the association between a protein-restrictive diet and its intergenerational impact on kidney development remains unclear. Methods: We conducted mu
Externí odkaz:
https://doaj.org/article/5646be61cf85474d9517caa9b7ffbfed
Autor:
Zubaida Saifudeen, Jiao Liu, Susana Dipp, Xiao Yao, Yuwen Li, Nathaniel McLaughlin, Karam Aboudehen, Samir S El-Dahr
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44869 (2012)
Congenital reduction in nephron number (renal hypoplasia) is a predisposing factor for chronic kidney disease and hypertension. Despite identification of specific genes and pathways in nephrogenesis, determinants of final nephron endowment are poorly
Externí odkaz:
https://doaj.org/article/5c50b90e324a4f099cced84c903b7671
Autor:
Fabiola Diniz, Nguyen Yen Nhi Ngo, Mariel Colon-Leyva, Francesca Edgington-Giordano, Sylvia Hilliard, Kevin Zwezdaryk, Jiao Liu, Samir S. El-Dahr, Giovane G. Tortelote
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Nephron endowment at birth impacts long-term renal and cardiovascular health, and it is contingent on the nephron progenitor cell (NPC) pool. Glycolysis modulation is essential for determining NPC fate, but the underlying mechanism is unclea
Externí odkaz:
https://doaj.org/article/23ad3644edca43628130dae686ae3d97
Autor:
Fenglin Wang, Jenny Ngo, Yuwen Li, Hongbing Liu, Chao-Hui Chen, Zubaida Saifudeen, Maria Luisa S Sequeira-Lopez, Samir S. El-Dahr
Publikováno v:
Epigenetics, Vol 16, Iss 11, Pp 1235-1250 (2021)
The epigenetic regulator Dot1, the only known histone H3K79 methyltransferase, has a conserved role in organismal development and homoeostasis. In yeast, Dot1 is required for telomeric silencing and genomic integrity. In Drosophila, Dot1 (Grappa) reg
Externí odkaz:
https://doaj.org/article/5d42d923eca444e0bdd6b5738e4a3c6b
Autor:
Sylvia Hilliard, Renfang Song, Hongbing Liu, Chao-hui Chen, Yuwen Li, Melody Baddoo, Erik Flemington, Alanna Wanek, Jay Kolls, Zubaida Saifudeen, Samir S. El-Dahr
Publikováno v:
Biology Open, Vol 8, Iss 5 (2019)
Six2+ cap mesenchyme cells, also called nephron progenitor cells (NPC), are precursors of all epithelial cell types of the nephron, the filtering unit of the kidney. Current evidence indicates that perinatal ‘old’ NPC have a greater tendency to e
Externí odkaz:
https://doaj.org/article/0cd0ec4a59ae40ed910bd19e03746fd7
Autor:
Courtney M Dugas, Samir S. El-Dahr, Stacy M Yanofsky, Jiao Liu, Ryousuke Satou, Akemi Katsurada, Zubaida Saifudeen
Publikováno v:
Am J Physiol Renal Physiol
Human kidney organoid technology holds promise for novel kidney disease treatment strategies and utility in pharmacological and basic science. Given the crucial roles of the intrarenal renin-angiotensin system (RAS) and angiotensin II (ANG II) in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d978df54a2ee58e3e0d5d2926398f4ae
https://doi.org/10.1152/ajprenal.00134.2021
https://doi.org/10.1152/ajprenal.00134.2021
Autor:
Eman A. Toraih, Manal S. Fawzy, Bo Ning, Mourad Zerfaoui, Youssef Errami, Emmanuelle M. Ruiz, Mohammad H. Hussein, Muhib Haidari, Melyssa Bratton, Giovane G. Tortelote, Sylvia Hilliard, Naris Nilubol, Jonathon O. Russell, Mohamed A. Shama, Samir S. El-Dahr, Krzysztof Moroz, Tony Hu, Emad Kandil
Publikováno v:
Cancers; Volume 14; Issue 17; Pages: 4128
Papillary thyroid carcinomas (PTCs) account for most endocrine tumors; however, screening and diagnosing the recurrence of PTC remains a clinical challenge. Using microRNA sequencing (miR-seq) to explore miRNA expression profiles in PTC tissues and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523f2fdc1ba2ec8e157c383331922dc8
https://pubmed.ncbi.nlm.nih.gov/36077665
https://pubmed.ncbi.nlm.nih.gov/36077665
Autor:
Samir S. El-Dahr
Publikováno v:
Journal of the American Society of Nephrology. 32:2687-2689
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10b7d7be9f511c4eb6167f0163110623
https://doi.org/10.1681/asn.2021081038
https://doi.org/10.1681/asn.2021081038
Autor:
Chao-Hui Chen, Samir S. El-Dahr, Jenny M. Ngo, Yuwen Li, Zubaida Saifudeen, Hongbing Liu, Maria Luisa S. Sequeira-Lopez, Fenglin Wang
Publikováno v:
Epigenetics
The epigenetic regulator Dot1, the only known histone H3K79 methyltransferase, has a conserved role in organismal development and homoeostasis. In yeast, Dot1 is required for telomeric silencing and genomic integrity. In Drosophila, Dot1 (Grappa) reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392ad449e8da95bfebb9b6d0ea61ae48
https://doi.org/10.1080/15592294.2020.1861168
https://doi.org/10.1080/15592294.2020.1861168