Corticosteroid-Related Adverse Events Systematically Increase with Corticosteroid Dose in Noninfectious Intermediate, Posterior, or Panuveitis

Autor: Yanjun Bao, Anne Camez, Avani Joshi, Manish Mittal, Samir R. Tari, Keith A. Betts, Jennifer E. Thorne, Eric B. Suhler

Publikováno v: Ophthalmology. 124:1799-1807

Purpose Chronic use of corticosteroids for the treatment of uveitis has been linked with drug-associated toxicity and adverse events (AEs). This study examines the association between corticosteroid dosage and incidence rates of corticosteroid-relate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b07d37050726d7eb8c75d6ee9afffd7f
https://doi.org/10.1016/j.ophtha.2017.06.017

Safety and Efficacy of Adalimumab in Patients with Noninfectious Uveitis in an Ongoing Open-Label Study: VISUAL III

Autor: Sophia Pathai, Jianzhong Liu, Glenn J. Jaffe, Martina Kron, Toshikatsu Kaburaki, Samir R. Tari, Alfredo Adán, Luca Cimino, Joachim Van Calster, Lyndell L Lim, Alexandra P. Song, Quan Dong Nguyen, Eric Fortin, Manfred Zierhut, Ariel Schlaen, Andrew D. Dick, Anne Camez, Antoine P. Brézin, Eric B. Suhler, Mirjam E.J. van Velthoven, Albert T. Vitale, Michal Kramer, Cristina Muccioli, Hiroshi Goto

Publikováno v: Suhler, E B, Adán, A, Brézin, A P, Fortin, E, Goto, H, Jaffe, G J, Kaburaki, T, Kramer, M, Lim, L L, Muccioli, C, Nguyen, Q D, Van Calster, J, Cimino, L, Kron, M, Song, A P, Liu, J, Pathai, S, Camez, A, Schlaen, A, van Velthoven, M E J, Vitale, A T, Zierhut, M, Tari, S & Dick, A D 2018, ' Safety and Efficacy of Adalimumab in Patients with Noninfectious Uveitis in an Ongoing Open-Label Study : VISUAL III ', Ophthalmology, vol. 125, no. 7, pp. 1075-1087 . https://doi.org/10.1016/j.ophtha.2017.12.039

PURPOSE: To evaluate safety and efficacy of adalimumab in patients with noninfectious intermediate, posterior, or panuveitis. DESIGN: Phase 3, open-label, multicenter clinical trial extension (VISUAL III). PARTICIPANTS: Adults meeting treatment failu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8f86f1a04d653528b0eaa4bbca8c47
https://pubmed.ncbi.nlm.nih.gov/29429764

Prevalence of Noninfectious Uveitis in the United States: A Claims-Based Analysis

Autor: Martha Skup, Arijit Ganguli, Eric B. Suhler, Samir R. Tari, Jennifer E. Thorne, Dendy Macaulay, Jingdong Chao

Publikováno v: JAMA ophthalmology. 134(11)

Importance Noninfectious uveitis (NIU) is a collection of intraocular inflammatory disorders that may be associated with significant visual impairment. To our knowledge, few studies have investigated NIU prevalence overall or stratified by inflammati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124dc45168d9c91600d4a4a16299ca5c
https://pubmed.ncbi.nlm.nih.gov/27607536

Adalimumab for prevention of uveitic flare in patients with inactive non-infectious uveitis controlled by corticosteroids (VISUAL II): a multicentre, double-masked, randomised, placebo-controlled phase 3 trial

Autor: Anne Camez, Samir R. Tari, Antoine P. Brézin, Shree Kurup, Luca Cimino, Quan Dong Nguyen, Ariel Schlaen, Carlos Pavesio, Glenn J. Jaffe, Nisha V. Kwatra, John D. Sheppard, Alexandra P. Song, Joachim Van Calster, Pauline T. Merrill, Martina Kron, Andrew D. Dick

Publikováno v: Nguyen, Q D, Merrill, P T, Jaffe, G J, Dick, A D, Kurup, S K, Sheppard, J, Schlaen, A, Pavesio, C, Cimino, L, Van Calster, J, Camez, A A, Kwatra, N V, Song, A P, Kron, M, Tari, S & Brézin, A P 2016, ' Adalimumab for prevention of uveitic flare in patients with inactive non-infectious uveitis controlled by corticosteroids (VISUAL II) : a multicentre, double-masked, randomised, placebo-controlled phase 3 trial ', Lancet, vol. 388, no. 10050, pp. 1183-1192 . https://doi.org/10.1016/S0140-6736(16)31339-3

BackgroundNon-infectious uveitis is a potentially sight-threatening ocular disorder caused by chronic inflammation and its complications. Therapeutic success is limited by systemic adverse effects associated with long-term corticosteroid and immunomo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa636421c21bde5ca36a7eef02cfe326
https://hdl.handle.net/11380/1259080

Electroretinography and microperimetry as noninvasive diagnostic tools for cilioretinal artery occlusion

Autor: Samir R. Tari, Vivienne C. Greenstein, Lama A. Al-Aswad, Stephen H. Tsang

Publikováno v: Retinal casesbrief reports. 2(2)

PURPOSE To report a case of cilioretinal artery occlusion with normal fluorescein angiography findings that was evaluated by electroretinography (ERG) and microperimetry. METHODS A 64-year-old-man presented with an oval paracentral scotoma in the tem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ad1023257797d8b1bd88a3065d058d
https://pubmed.ncbi.nlm.nih.gov/25389831