Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Samir P. Bhagwat"'
Autor:
Samir P. Bhagwat, Francis Gigliotti, Jing Wang, Zhengdong Wang, Robert H. Notter, Patrick S. Murphy, Fátima Rivera-Escalera, Jane Malone, Michael B. Jordan, Michael R. Elliott, Terry W. Wright
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Invasive fungal infections, including Pneumocystis Pneumonia (PcP), remain frequent life-threatening conditions of patients with adaptive immune defects. While innate immunity helps control pathogen growth early during infection, it is typically not
Externí odkaz:
https://doaj.org/article/20785d1ecb0d49d5ac2fc5a9a16d5aad
Autor:
Zachary Hoy, Jing Wang, Achsah D. Keegan, Samir P. Bhagwat, Zhuo-Qian Zhang, Terry W. Wright, Francis Gigliotti
Publikováno v:
Infection and Immunity. 83:4594-4603
Pneumocystis is a respiratory fungal pathogen that causes pneumonia ( Pneumocystis pneumonia [PcP]) in immunocompromised patients. Alveolar macrophages are critical effectors for CD4 + T cell-dependent clearance of Pneumocystis , and previous studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6a7eb38a0fd568e6a963347ca0c921
https://doi.org/10.1128/iai.00763-15
https://doi.org/10.1128/iai.00763-15
Autor:
William J. Janssen, Samir P. Bhagwat, Michael R. Elliott, Jing Wang, Terry W. Wright, Patrick S. Murphy, Joshua Munger
The phagocytosis of apoptotic cells (efferocytosis) shifts macrophages to an anti-inflammatory state through a set of still poorly understood soluble and cell-bound signals. Apoptosis is a common feature of inflamed tissues, and efferocytosis by tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6266c7dd3eb7af9fe52ff4a05adec0ff
https://europepmc.org/articles/PMC5344214/
https://europepmc.org/articles/PMC5344214/
Publikováno v:
The Journal of Immunology. 184:497-502
The T cell–mediated immune response elicited by Pneumocystis plays a key role in pulmonary damage and dysfunction during Pneumocystis carinii pneumonia (PcP). Mice depleted of CD4+ and CD8+ T cells prior to infection are markedly protected from PcP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104991589150c6901318e2aa4c18ac3d
https://doi.org/10.4049/jimmunol.0901864
https://doi.org/10.4049/jimmunol.0901864
Autor:
Samir P. Bhagwat, Gloria S. Pryhuber, Francis Gigliotti, Terry W. Wright, Michael A. O'Reilly, Jacob N. Finkelstein, Heidie Huyck
Publikováno v:
The Journal of Immunology. 181:1409-1419
The opportunistic organism Pneumocystis carinii (Pc) produces a life-threatening pneumonia (PcP) in patients with low CD4+ T cell counts. Animal models of HIV-AIDS-related PcP indicate that development of severe disease is dependent on the presence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::788e9e0c907232688798d4f7d09e6284
https://doi.org/10.4049/jimmunol.181.2.1409
https://doi.org/10.4049/jimmunol.181.2.1409
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 292:L1495-L1505
Pneumocystis carinii is an opportunistic fungal pathogen that causes pneumonia (PCP) in immunocompromised individuals. Recent studies have demonstrated that the host's immune response is clearly responsible for the majority of the pathophysiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa75516f7c11c922684c53f9377e1ee
https://doi.org/10.1152/ajplung.00452.2006
https://doi.org/10.1152/ajplung.00452.2006
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 291:L1256-L1266
Immune-mediated lung injury is an important component of Pneumocystis pneumonia (PcP)-related immunorestitution disease (IRD). However, the individual contribution of CD4+and CD8+T cells to the pathophysiology of IRD remains undetermined. Therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b04502ee95374703776e202271982dc
https://doi.org/10.1152/ajplung.00079.2006
https://doi.org/10.1152/ajplung.00079.2006
Publikováno v:
Infection and Immunity. 74:6310-6316
While CD8+cells have been shown to contribute to lung injury duringPneumocystis cariniipneumonia (PCP), there are conflicting reports concerning the ability of CD8+cells to killP. carinii.To address these two issues, we studied the effect of the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b377f60c9f61d2f86529abb75431cad
https://doi.org/10.1128/iai.00668-06
https://doi.org/10.1128/iai.00668-06
Publikováno v:
FEMS Microbiology Letters. 205:225-230
Streptococcus mutans has at least six pairs of open reading frames that are homologous to bacterial two-component regulatory systems. Putative response regulators from five out of six of these pairs were successfully mutated by insertion of a kanamyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d46b45c952d53aa9c578b683695b9c
https://doi.org/10.1111/j.1574-6968.2001.tb10952.x
https://doi.org/10.1111/j.1574-6968.2001.tb10952.x
Publikováno v:
C24. PNEUMOCYSTIS AND OTHER FUNGAL PNEUMONIAS: PATHOGENESIS AND CLINICAL CONSEQUENCES.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c7fa07a766afe545f73bea347d82adf
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4136
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4136