Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Samir Morsli"'
Autor:
Samir Morsli, Catarina M. Henriques, Pamela S. Ellis, Heather Mortiboys, Sarah Baxendale, Catherine A. Loynes, Stephen A. Renshaw, Ilaria Bellantuono
Senescence drives the onset and severity of multiple ageing-associated diseases as well as frailty. As a result, there has been an increased interest in mechanistic studies and in the search for compounds targeting senescent cells, known as senolytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83230762a3164841ca2b79ff05df935b
https://doi.org/10.1101/2022.09.19.506911
https://doi.org/10.1101/2022.09.19.506911
Autor:
Estela González-Gualda, David Macias, Samir Morsli, José Ezequiel Martín, Hui-Ling Ou, Mary Denholm, Ioana Olan, Reuben Hoffmann, Mark Dane, Dimitris Veroutis, Guillermo Medrano, Francisca Mulero, Carla P. Martins, Mariano Barbacid, Vassilis Gorgoulis, James E. Korkola, Doris M. Rassl, Gary J. Doherty, Robert C. Rintoul, Masashi Narita, Daniel Muñoz-Espín
Platinum-based chemotherapy is commonly used for non-small cell lung cancer (NSCLC) treatment, yet clinical outcomes remain poor. Cellular senescence and its associated secretory phenotype (SASP) can have multiple tumour-promoting activities, althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b2bb945606577f05bb5051e573af309
https://doi.org/10.1101/2022.08.01.502019
https://doi.org/10.1101/2022.08.01.502019
Autor:
Ilaria Bellantuono, Samir Morsli
Publikováno v:
Mechanisms of ageing and development. 193
Over 60 % of people over the age of 65 will suffer from multiple diseases concomitantly but the common approach is to treat each disease separately. As age-associated diseases have common underlying mechanisms there is potential to tackle many diseas