Neurodevelopmental outcomes following possible serious bacterial infection in early infancy in Karachi, Pakistan: a prospective cohort study

Autor: Nudrat Farheen, Shahira Shahid, Kiran Ramzan Ali Lalani, Iqbal Azam, Farah Khalid, Batool Fatima, Mohammad Shahidul Islam, Samir K. Saha, Shamim Ahmad Qazi, Fyezah Jehan, Muhammad Imran Nisar

Publikováno v: BMC Pediatrics, Vol 24, Iss 1, Pp 1-12 (2024)

Abstract Background Pakistan reports a significant burden of neonatal mortality, with infections as one of the major causes. We aim to assess the long-term impact of early infancy infections on neurodevelopmental outcomes during later childhood. Meth

Externí odkaz: https://doaj.org/article/e1b234f4860a4d3e83f2c59da9037e45

Safety and efficacy of whole-body chlorhexidine gluconate cleansing with or without emollient in hospitalised neonates (NeoCHG): a multicentre, randomised, open-label, factorial pilot trialResearch in context

Autor: Neal Russell, Michelle N. Clements, Kazi Shammin Azmery, Adrie Bekker, Julia Bielicki, Angela Dramowski, Sally Ellis, Aaqilah Fataar, Mahbubul Hoque, Kristen LeBeau, Seamus O’Brien, Francesca Schiavone, Peter Skoutari, Mohammad Shahidul Islam, Samir K. Saha, Ann Sarah Walker, Andrew Whitelaw, Michael Sharland

Publikováno v: EClinicalMedicine, Vol 69, Iss , Pp 102463- (2024)

Summary: Background: Healthcare-associated infections account for substantial neonatal in-hospital mortality. Chlorhexidine gluconate (CHG) whole body skin application could reduce sepsis by lowering bacterial colonisation density, although safety an

Externí odkaz: https://doaj.org/article/2c38f42d402f40dba2d064108c4b88ee

In-hospital mortality risk stratification in children aged under 5 years with pneumonia with or without pulse oximetry: A secondary analysis of the Pneumonia REsearch Partnership to Assess WHO REcommendations (PREPARE) dataset

Autor: Shubhada Hooli, Carina King, Eric D. McCollum, Tim Colbourn, Norman Lufesi, Charles Mwansambo, Christopher J. Gregory, Somsak Thamthitiwat, Clare Cutland, Shabir Ahmed Madhi, Marta C. Nunes, Bradford D. Gessner, Tabish Hazir, Joseph L. Mathew, Emmanuel Addo-Yobo, Noel Chisaka, Mumtaz Hassan, Patricia L. Hibberd, Prakash Jeena, Juan M. Lozano, William B. MacLeod, Archana Patel, Donald M. Thea, Ngoc Tuong Vy Nguyen, Syed MA. Zaman, Raul O. Ruvinsky, Marilla Lucero, Cissy B. Kartasasmita, Claudia Turner, Rai Asghar, Salem Banajeh, Imran Iqbal, Irene Maulen-Radovan, Greta Mino-Leon, Samir K. Saha, Mathuram Santosham, Sunit Singhi, Shally Awasthi, Ashish Bavdekar, Monidarin Chou, Pagbajabyn Nymadawa, Jean-William Pape, Glaucia Paranhos-Baccala, Valentina Sanchez Picot, Mala Rakoto-Andrianarivelo, Vanessa Rouzier, Graciela Russomando, Mariam Sylla, Philippe Vanhems, Jianwei Wang, Sudha Basnet, Tor A. Strand, Mark I. Neuman, Luis Martinez Arroyo, Marcela Echavarria, Shinjini Bhatnagar, Nitya Wadhwa, Rakesh Lodha, Satinder Aneja, Angela Gentile, Mandeep Chadha, Siddhivinayak Hirve, Kerry-Ann F. O'Grady, Alexey W. Clara, Chris A. Rees, Harry Campbell, Harish Nair, Jennifer Falconer, Linda J. Williams, Margaret Horne, Shamim A. Qazi, Yasir Bin Nisar

Publikováno v: International Journal of Infectious Diseases, Vol 129, Iss , Pp 240-250 (2023)

Objectives: We determined the pulse oximetry benefit in pediatric pneumonia mortality risk stratification and chest-indrawing pneumonia in-hospital mortality risk factors. Methods: We report the characteristics and in-hospital pneumonia-related morta

Externí odkaz: https://doaj.org/article/56557afcf42b4085b27b14e04af13136

Patterns of antibiotic use, pathogens, and prediction of mortality in hospitalized neonates and young infants with sepsis: A global neonatal sepsis observational cohort study (NeoOBS)

Autor: Neal J. Russell, Wolfgang Stöhr, Nishad Plakkal, Aislinn Cook, James A. Berkley, Bethou Adhisivam, Ramesh Agarwal, Nawshad Uddin Ahmed, Manica Balasegaram, Daynia Ballot, Adrie Bekker, Eitan Naaman Berezin, Davide Bilardi, Suppawat Boonkasidecha, Cristina G. Carvalheiro, Neema Chami, Suman Chaurasia, Sara Chiurchiu, Viviane Rinaldi Favarin Colas, Simon Cousens, Tim R. Cressey, Ana Carolina Dantas de Assis, Tran Minh Dien, Yijun Ding, Nguyen Trong Dung, Han Dong, Angela Dramowski, Madhusudhan DS, Ajay Dudeja, Jinxing Feng, Youri Glupczynski, Srishti Goel, Herman Goossens, Doan Thi Huong Hao, Mahmudul Islam Khan, Tatiana Munera Huertas, Mohammad Shahidul Islam, Daniel Jarovsky, Nathalie Khavessian, Meera Khorana, Angeliki Kontou, Tomislav Kostyanev, Premsak Laoyookhon, Sorasak Lochindarat, Mattias Larsson, Maia De Luca, Surbhi Malhotra-Kumar, Nivedita Mondal, Nitu Mundhra, Philippa Musoke, Marisa M. Mussi-Pinhata, Ruchi Nanavati, Firdose Nakwa, Sushma Nangia, Jolly Nankunda, Alessandra Nardone, Borna Nyaoke, Christina W. Obiero, Maxensia Owor, Wang Ping, Kanchana Preedisripipat, Shamim Qazi, Lifeng Qi, Tanusha Ramdin, Amy Riddell, Lorenza Romani, Praewpan Roysuwan, Robin Saggers, Emmanuel Roilides, Samir K. Saha, Kosmas Sarafidis, Valerie Tusubira, Reenu Thomas, Sithembiso Velaphi, Tuba Vilken, Xiaojiao Wang, Yajuan Wang, Yonghong Yang, Liu Zunjie, Sally Ellis, Julia A. Bielicki, A. Sarah Walker, Paul T. Heath, Mike Sharland

Publikováno v: PLoS Medicine, Vol 20, Iss 6 (2023)

Background There is limited data on antibiotic treatment in hospitalized neonates in low- and middle-income countries (LMICs). We aimed to describe patterns of antibiotic use, pathogens, and clinical outcomes, and to develop a severity score predicti

Externí odkaz: https://doaj.org/article/9e5be23d1391479c885c0de7244404cb

Community-based asthma assessment in young children: adaptations for a multicentre longitudinal study in South Asia

Autor: Mohammad Shahidul Islam, Samin Huq, Steven Cunningham, Jurgen Schwarze, A.S.M.D. Ashraful Islam, Mashal Amin, Farrukh Raza, Radanath Satpathy, Pradipta Ranjan Rauta, Salahuddin Ahmed, Hana Mahmood, Genevie Fernandes, Benazir Baloch, Imran Nisar, Sajid Soofi, Pinaki Panigrahi, Sanjay Juvekar, Ashish Bavkedar, Abdullah H. Baqui, Senjuti Saha, Harry Campbell, Aziz Sheikh, Harish Nair, Samir K. Saha

Publikováno v: Therapeutic Advances in Infectious Disease, Vol 9 (2022)

Background: Systematic assessment of childhood asthma is challenging in low- and middle-income country (LMIC) settings due to the lack of standardised and validated methodologies. We describe the contextual challenges and adaptation strategies in the

Externí odkaz: https://doaj.org/article/7dada08402524186a4848a9164445433