Premature differentiation of nephron progenitor cell and dysregulation of gene pathways critical to kidney development in a model of preterm birth

Autor: Aleksandra Cwiek, Masako Suzuki, Kimberly deRonde, Mark Conaway, Kevin M. Bennett, Samir El Dahr, Kimberly J. Reidy, Jennifer R. Charlton

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)

Abstract Preterm birth is a leading cause of neonatal morbidity. Survivors have a greater risk for kidney dysfunction and hypertension. Little is known about the molecular changes that occur in the kidney of individuals born preterm. Here, we demonst

Externí odkaz: https://doaj.org/article/18b43f87c303431d9d6ae315e4174c3d

Gene length is a pivotal feature to explain disparities in transcript capture between single transcriptome techniques

Autor: Ricardo R. Pavan, Fabiola Diniz, Samir El-Dahr, Giovane G. Tortelote

Publikováno v: Frontiers in Bioinformatics, Vol 3 (2023)

The scale and capability of single-cell and single-nucleus RNA-sequencing technologies are rapidly growing, enabling key discoveries and large-scale cell mapping operations. However, studies directly comparing technical differences between single-cel

Externí odkaz: https://doaj.org/article/ef25d0f0e99f48a3a81c6fd0e210dcaa

Overactivation of histone deacetylases and EZH2 in Wilms tumorigenesis

Autor: Chao-Hui Chen, Nguyen Yen Nhi Ngo, Alun Wang, Samir El-Dahr, Hongbing Liu

Publikováno v: Genes & Diseases.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9069568512a5fffe6987362b88826f2
https://doi.org/10.1016/j.gendis.2022.10.026

Blood Pressure Classification Status in Children With CKD Following Adoption of the 2017 American Academy of Pediatrics Guideline

Autor: Derek K. Ng, Megan K. Carroll, Susan L. Furth, Bradley A. Warady, Joseph T. Flynn, Sahar Fathallah-Shaykh, Anjali Nayak, Martin Turman, Tom Blydt-Hansen, Cynthia Wong, Steve Alexander, Ora Yadin, Elizabeth Ingulli, Robert Mak, Cheryl Sanchez-Kazi, Asha Moudgil, Caroline Gluck, Carolyn Abitbol, Marissa DeFrietas, Chryso Katsoufis, Wacharee Seeherunvong, Larry Greenbaum, Lyndsay Harshman, Craig Langman, H. Ann & Robert, Sonia Krishnan, Amy Wilson, Stefan Kiessling, Margaret Murphy, Siddharth Shah, Janice Sullivan, Sushil Gupta, Samir El-Dahr, Stacy Drury, Nancy Rodig, Allison Dart, Meredith Atkinson, Arlene Gerson, Tej Matoo, Zubin Modi, Alejandro Quiroga, Bradley Warady, Rebecca Johnson, Vikas Dharnidharka, Stephen Hooper, Susan Massengill, Liliana Gomez-Mendez, Matthew Hand, Joann Carlson, Hanan Tawadrous, Roberto Jodorkovsky, Craig Wong, Frederick Kaskel, Shlomo Shinnar, Jeffrey Saland, Marc Lande, George Schwartz, Anil Mongia, Donna Claes, Mark Mitsnefes, Katherine Dell, Hiren Patel, Pascale Lane, Rulan Parekh, Amira Al-Uzri, Kelsey Richardson, Susan Furth, Larry Copelovitch, Elaine Ku, Joshua Samuels, Poyyapakkam Srivaths, Samhar Al-Akash, Patricia Seo-Mayer, Victoria Norwood, Joseph Flynn, Cynthia Pan, Sharon Bartosh

Publikováno v: American journal of kidney diseases : the official journal of the National Kidney Foundation.

Accurate detection of hypertension is crucial for clinical management of pediatric chronic kidney disease (CKD). The 2017 American Academy of Pediatrics childhood hypertension guidelines included new normative blood pressure (BP) values and revised d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95eb690ab49ebe457f19201ecb3d4720
https://pubmed.ncbi.nlm.nih.gov/36521780

Premature differentiation of nephron progenitors and dysregulation of gene pathways critical to kidney development in a model of preterm birth

Autor: Aleksandra Cwiek, Masako Suzuki, Kimberly deRonde, Mark Conaway, Kevin Bennett, Samir El Dahr, Kimberly Reidy, Jennifer Charlton

Preterm birth is a leading cause of neonatal morbidity. Survivors have a greater risk for kidney dysfunction and hypertension. Little is known about the molecular changes that occur in the kidney of individuals born preterm. Here, we demonstrate that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59a9755d265ac015bbc76061739c2d19
https://doi.org/10.21203/rs.3.rs-444923/v1