Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Samim Loftus"'
Autor:
Brian P. Kirby, John L. Waddington, Orna Tighe, Emilie Petit I, Steve Wilson, Lieve Desbonnet, Rachel Cox, Samim Loftus, Colm M. P. O’Tuathaigh, Gerard Clarke, Christina M. Payne, John F. Cryan, Timothy G. Dinan
Publikováno v:
Neuroscience Letters. 736:135218
Dysbindin-1 is implicated in several aspects of schizophrenia, including cognition and both glutamatergic and dopaminergic neurotransmission. Targeted knockout of dysbindin-1A (Dys-1A KO), the most abundant and widely expressed isoform in the brain,
Autor:
John F. Cryan, Gerard Clarke, John L. Waddington, Francesc Perez-Branguli, Donna Lai, Emilie Petit, Marco A. Riva, Claire O'Leary, Samim Loftus, Rachel Cox, Timothy G. Dinan, Richard P. Harvey, Fabio Fumagalli, Lieve Desbonnet, Gerard M. Moloney, Orna Tighe, Kevin J. Mitchell, Colm M. P. O’Tuathaigh
Publikováno v:
Schizophrenia bulletin. 43(1)
Few studies have addressed likely gene × gene (ie, epistatic) interactions in mediating risk for schizophrenia. Using a preclinical genetic approach, we investigated whether simultaneous disruption of the risk factors Neuregulin-1 (NRG1) and Disrupt