765 NG-350A, a tumor-selective anti-CD40 agonist expressing therapeutic, gemcitabine/nab-paclitaxel and ipilimumab for untreated metastatic pancreatic adenocarcinoma: cohort C of the REVOLUTION trial

Autor: Robert H Vonderheide, Andrew H Ko, Danny Khalil, Oliver Rosen, Robert A Wolff, James Francis, Samantha Bucktrout, Christopher R Cabanski, Silvia Boffo, Zev A Wainberg, Samik Upadhaya, Eileen M O’Reilly, Mark H O’Hara, George Fisher, Jamie Arnott, Ana Rosa Saez-Ibanez, Jay Campbell, Ute Dugan, Jill O’Donnell-Tormey

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Externí odkaz: https://doaj.org/article/b601525223344c068784d6ee00423943

Immunotherapy in triple negative breast cancer: beyond checkpoint inhibitors

Autor: Yara Abdou, Atta Goudarzi, Jia Xin Yu, Samik Upadhaya, Benjamin Vincent, Lisa A. Carey

Publikováno v: npj Breast Cancer, Vol 8, Iss 1, Pp 1-10 (2022)

Abstract The development of immunotherapy agents has revolutionized the field of oncology. The only FDA-approved immunotherapeutic approach in breast cancer consists of immune checkpoint inhibitors, yet several novel immune-modulatory strategies are

Externí odkaz: https://doaj.org/article/dbf26895bdc04849b022584f378e24e0

Assessing Interdisciplinary Learning and Student Activism in a Water Issues Course

Autor: Stephen J. Juris, Anja Mueller, Cathy Willermet, Eron Drake, Samik Upadhaya, Pratik Chhetri

Publikováno v: Journal of the Scholarship of Teaching and Learning, Vol 14, Iss 2 (2014)

In response to a request from a campus student organization, faculty from three fields came together to develop and teach an integrated interdisciplinary course on water issues and social activism. This course, “Water as Life, Death, and Power”,

Externí odkaz: https://doaj.org/article/a3b13302c2f1405d8e323af64bb9bf46

Stem cell decoupling underlies impaired lymphoid development during aging

Autor: Geunhyo Jang, Stephania Contreras Castillo, Eduardo Esteva, Samik Upadhaya, Jue Feng, Nicholas M. Adams, Elodie Richard, Rajeshwar Awatramani, Catherine M. Sawai, Boris Reizis

Publikováno v: Proceedings of the National Academy of Sciences. 120

Mammalian aging is associated with multiple defects of hematopoiesis, most prominently with the impaired development of T and B lymphocytes. This defect is thought to originate in hematopoietic stem cells (HSCs) of the bone marrow, specifically due t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3009db661f00b30912dccf2b1585afe
https://doi.org/10.1073/pnas.2302019120

Impact of COVID-19 on Pancreatic Cancer Research and the Path Forward

Autor: Samik Upadhaya, Raffaella Casolino, Antonio Pea, Vincenzo Corbo, Chiara Braconi, Elisa Giovannetti, Paola Cappello, Geny Piro, Lorena Torroni, Miriam Martini, Andrew V. Biankin, David K. Chang, Aldo Scarpa, Claudio Bassi, Michele Milella, Carmine Carbone, Sara Lovisa, Jay Campbell, Yu Jia Xin

Publikováno v: Gastroenterology
The PanCaCovid-19 Study Group 2021, ' Impact of COVID-19 on Pancreatic Cancer Research and the Path Forward ', Gastroenterology, vol. 161, no. 6, pp. 1758-1763 . https://doi.org/10.1053/j.gastro.2021.06.080
Gastroenterology, 161(6), 1758-1763. W.B. Saunders Ltd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ee50331c396f11a994f7163a2b8c3f
https://doi.org/10.1053/j.gastro.2021.06.080