Adolescent cannabinoid exposure modulates the vulnerability to cocaine-induced conditioned place preference and DNMT3a expression in the prefrontal cortex in Swiss mice

Autor: Samia R. L. Joca, A L Roncalho, Amanda J. Sales, Gabriela Pandini Silote, Nicole Rodrigues da Silva, P H Gobira

Publikováno v: Gobira, P H, Roncalho, A L, Silva, N R, Silote, G P, Sales, A J & Joca, S R 2021, ' Adolescent cannabinoid exposure modulates the vulnerability to cocaine-induced conditioned place preference and DNMT3a expression in the prefrontal cortex in Swiss mice ', Psychopharmacology, vol. 238, no. 11, pp. 3107-3118 . https://doi.org/10.1007/s00213-021-05926-4

Rationale: Cannabis sativa is the most widely used drug by adolescents globally. The recreational use of synthetic cannabinoids by teenagers has also grown in recent years. Despite the wrong perception that exposure to these drugs does not cause harm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff4334d57783df46dbac51011f7e871
https://pure.au.dk/portal/da/publications/adolescent-cannabinoid-exposure-modulates-the-vulnerability-to-cocaineinduced-conditioned-place-preference-and-dnmt3a-expression-in-the-prefrontal-cortex-in-swiss-mice(fc3cc42e-88ec-4403-9396-8f864ea3937c).html

Cannabidiol as an add-on therapy to overcome the slow-onset and, possibly, resistance to antidepressant treatment: involvement of NAPE-PLD in the medial prefrontal cortex

Autor: Ken Mackie, Fusse Ej, Maria Adrielle Vicente, Franciele F. Scarante, Guimarães Fs, Carlos Arterio Sorgi, Davi Silveira Scomparin, Campos Ac, Crippa Jas, Araújo Mr, Lopes Vd, Aguiar Rp, Hallak Jec, Samia R. L. Joca, Nardini, Lúcia Helena Faccioli, Antonio Waldo Zuardi

Antidepressants such as serotonin uptake inhibitors are the first-line pharmacological treatment for chronic stress-related psychiatric disorders. However, their late-onset therapeutic action and frequent side effects, however, are important challeng

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::60451f3c59b2b34199edec89973994a2
https://doi.org/10.1101/2021.04.23.441143

Putative effects of cannabidiol in depression and synaptic plasticity

Autor: Francisco Eduardo Gontijo Guimarães, Ariandra G. Sartim, Gregers Wegener, Amanda J. Sales, Samia R. L. Joca, Gabriela Pandini Silote

Significant limitations with the currently available antidepressant treatment strategies have inspired research on finding new and more efficient drugs to treat depression. Cannabidiol (CBD) is a nonpsychotomimetic component of Cannabis sativa and pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37d64406ec7f5ac602ca9c64c5ab1a68
https://doi.org/10.1016/b978-0-12-817933-8.00052-9

Hippocampal mammalian target of rapamycin is implicated in stress-coping behavior induced by cannabidiol in the forced swim test

Autor: Francisco Silveira Guimarães, Ariandra G. Sartim, Samia R. L. Joca, Amanda J. Sales

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Sartim, A G, Sales, A J, Guimarães, F S & Joca, S R 2018, ' Hippocampal mammalian target of rapamycin is implicated in stress-coping behavior induced by cannabidiol in the forced swim test ', Journal of Psychopharmacology, vol. 32, no. 8, pp. 922-931 . https://doi.org/10.1177/0269881118784877

Background: Cannabidiol is a non-psychotomimetic compound with antidepressant-like effects. However, the mechanisms and brain regions involved in cannabidiol effects are not yet completely understood. Brain-derived neurotrophic factor/tropomyosin-rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd47c775e13a5a364ceade2fcf3ee025
https://doi.org/10.1177/0269881118784877

Cannabidiol in Mental Health Disorders

Autor: Alline C. Campos, Felipe V. Gomes, Francisco Silveira Guimarães, Samia R. L. Joca

Publikováno v: Cannabis as Medicine ISBN: 9780429054723

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::087638cd318bd42b849b027144a699ba
https://doi.org/10.1201/9780429054723-10