Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Samia Ait-Mohand"'
Autor:
Marie-Christine Milot, Ophélie Bélissant-Benesty, Véronique Dumulon-Perreault, Samia Ait-Mohand, Sameh Geha, Patrick O. Richard, Étienne Rousseau, Brigitte Guérin
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionWe have previously shown that copper-64 (64Cu)-DOTHA2-PSMA can be used for positron emission tomography (PET) imaging of prostate cancer. Owing to the long-lasting, high tumoral uptake of 64Cu-DOTHA2-PSMA, the objective of the current stu
Externí odkaz:
https://doaj.org/article/f832897046684f62a147ccc61a2f10bc
Publikováno v:
EJNMMI Research, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Background Imaging diagnosis of inflammation has been challenging for many years. Inflammation imaging agents commonly used in nuclear medicine, such as [67Ga]Ga-citrate and 2-deoxy-2-[18F]fluoro-d-glucose ([18F]FDG) showed some limitations.
Externí odkaz:
https://doaj.org/article/86fa89391be24092b807f30663b971f1
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
To overcome resistance to chemotherapy for colorectal cancer, we propose to validate in vivo a novel terpyridine-platinum (TP) compound radiolabeled with the radio-theranostic isotope 64Cu. In vivo stability, biodistribution, PET imaging, tumor growt
Externí odkaz:
https://doaj.org/article/d78b636428ed421eb89348690392f5cf
Autor:
Aiman H. Alnahwi, Samia Ait-Mohand, Véronique Dumulon-Perreault, Yves L. Dory, Brigitte Guérin
Publikováno v:
ACS Omega, Vol 5, Iss 19, Pp 10731-10739 (2020)
Externí odkaz:
https://doaj.org/article/1ed2359947ed4611adce177b6c164c2d
Autor:
Marie-Christine Milot, Ophélie Bélissant Benesty, Véronique Dumulon-Perreault, Samia Ait-Mohand, Patrick O. Richard, Étienne Rousseau, Brigitte Guérin
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 996 (2022)
Prostate cancer imaging and late-stage management can be improved with prostate-specific membrane antigen (PSMA)-targeting radiotracers. We developed a PSMA positron emission tomography (PET) radiotracer, DOTHA2-PSMA radiolabeled with 64Cu (T1/2: 12.
Externí odkaz:
https://doaj.org/article/da57f08ae3e042e59080ccf2ccb670d6
Publikováno v:
Nanomaterials, Vol 11, Iss 9, p 2154 (2021)
Maximum benefits of chemoradiation therapy with platinum-based compounds are expected if the radiation and the drug are localized simultaneously in cancer cells. To optimize this concomitant effect, we developed the novel chemoradiotherapeutic agent
Externí odkaz:
https://doaj.org/article/bf084fc4b0ec47a4b6209cee774eea7f
Autor:
Frédéric Couture, Christine Levesque, Véronique Dumulon-Perreault, Samia Ait-Mohand, François D’Anjou, Robert Day, Brigitte Guérin
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 8, Pp 634-643 (2014)
The potential of PACE4 as a pharmacological target in prostate cancer has been demonstrated as this proprotein convertase is strongly overexpressed in human prostate cancer tissues and its inhibition, using molecular or pharmacological approaches, re
Externí odkaz:
https://doaj.org/article/4385aada31f04e14a1434a0ae825e80e
Autor:
Sébastien Tremblay, Jean-François Beaudoin, Ophélie Bélissant Benesty, Samia Ait-Mohand, Véronique Dumulon-Perreault, Étienne Rousseau, Éric E. Turcotte, Brigitte Guérin
Publikováno v:
Journal of Nuclear Medicine. 64:232-238
Publikováno v:
Journal of Medicinal Chemistry. 64:6765-6776
Terpyridine platinum (TP)-based chemotherapeutic agents target three-dimensional structures on DNA known as G-quadruplexes. We report the rational design and synthesis of a TP conjugate combined with copper-64 (64Cu), the decay characteristics of whi
Autor:
André C. Carpentier, Mélanie Archambault, Martin Lepage, Réjean Lebel, Christophe Noll, Luc Tremblay, Gabriel Richard, Brigitte Guérin, Samia Ait-Mohand, Denis P. Blondin
Publikováno v:
Magnetic Resonance in Medicine. 85:1625-1642
PURPOSE Determine if dynamic contrast enhanced (DCE) -MRI and/or 68 gallium 1,4,7,10-tetraazacyclododecane N, N', N″, N‴-tretraacetic acid (68 Ga-DOTA) positron emission tomography (PET) can assess perfusion in rat brown adipose tissue (BAT). Eva