Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sami S. Khaznadar"'
Autor:
Kenneth A. Jacobson, John A. Auchampach, Jinha Yu, Young-Hwan Jung, Amelia Bitant, Antonella Ciancetta, Zhan-Guo Gao, Philip Z. Mannes, Sami S. Khaznadar, David I. Lieberman
Publikováno v:
MedChemComm. 9:1920-1932
Recognition of nucleosides at adenosine receptors (ARs) is supported by multiple X-ray structures, but the structure of an adenine complex is unknown. We examined the selectivity of predicted A(1)AR and A(3)AR adenine antagonists that incorporated kn
Autor:
Liam J. O’Neil, Mariana J. Kaplan, Sami S. Khaznadar, Yudong Liu, Wanxia L. Tsai, Deborah L. Stone, Peter C. Grayson, Kenneth A. Jacobson, Jorge A Irizarry-Caro, Daniel L. Kastner, Carmelo Carmona-Rivera, Amanda K. Ombrello, Ivona Aksentijevich, Kyawt Win Shwin
Publikováno v:
Blood
Reduction of adenosine deaminase 2 (ADA2) activity due to autosomal-recessive loss-of-function mutations in the ADA2 gene (previously known as CECR1) results in a systemic vasculitis known as deficiency of ADA2 (DADA2). Neutrophils and a subset of ne
Autor:
Sami S. Khaznadar, Jorge A Irizarry-Caro, Daniella M. Schwartz, Carmelo Carmona-Rivera, Peter C. Grayson, Mariana J. Kaplan
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 70(3)
Objective Aberrant neutrophil extracellular trap (NET) formation has been implicated as a mechanism to induce auto-reactivity in at-risk individuals. The study objective was to assess whether medications implicated in cases of drug-induced autoimmuni
Publikováno v:
Cancer Research. 77:2786-2786
Introduction Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer. Survival rates have not been improved for decades and conventional therapy is effective in only 50% of the patients. Based on broad expression in up to 80-90%
Autor:
Yu J; Molecular Recognition Section , Laboratory of Bioorganic Chemistry , National Institute of Diabetes and Digestive and Kidney Diseases , National Institutes of Health , Bldg. 8A, Rm. B1A-19, NIH, NIDDK, LBC , Bethesda , Maryland 20892-0810 , USA . Email: kennethj@niddk.nih.gov ; ; Tel: +301 496 9024., Mannes P; Molecular Recognition Section , Laboratory of Bioorganic Chemistry , National Institute of Diabetes and Digestive and Kidney Diseases , National Institutes of Health , Bldg. 8A, Rm. B1A-19, NIH, NIDDK, LBC , Bethesda , Maryland 20892-0810 , USA . Email: kennethj@niddk.nih.gov ; ; Tel: +301 496 9024., Jung YH; Molecular Recognition Section , Laboratory of Bioorganic Chemistry , National Institute of Diabetes and Digestive and Kidney Diseases , National Institutes of Health , Bldg. 8A, Rm. B1A-19, NIH, NIDDK, LBC , Bethesda , Maryland 20892-0810 , USA . Email: kennethj@niddk.nih.gov ; ; Tel: +301 496 9024., Ciancetta A; School of Pharmacy , Queen's University Belfast , 96 Lisburn Rd , Belfast , BT9 7BL , UK., Bitant A; Department of Pharmacology , Medical College of Wisconsin , 8701 Watertown Plank Road , Milwaukee , Wisconsin 53226 , USA., Lieberman DI; Molecular Recognition Section , Laboratory of Bioorganic Chemistry , National Institute of Diabetes and Digestive and Kidney Diseases , National Institutes of Health , Bldg. 8A, Rm. B1A-19, NIH, NIDDK, LBC , Bethesda , Maryland 20892-0810 , USA . Email: kennethj@niddk.nih.gov ; ; Tel: +301 496 9024., Khaznadar S; Molecular Recognition Section , Laboratory of Bioorganic Chemistry , National Institute of Diabetes and Digestive and Kidney Diseases , National Institutes of Health , Bldg. 8A, Rm. B1A-19, NIH, NIDDK, LBC , Bethesda , Maryland 20892-0810 , USA . Email: kennethj@niddk.nih.gov ; ; Tel: +301 496 9024., Auchampach JA; Department of Pharmacology , Medical College of Wisconsin , 8701 Watertown Plank Road , Milwaukee , Wisconsin 53226 , USA., Gao ZG; Molecular Recognition Section , Laboratory of Bioorganic Chemistry , National Institute of Diabetes and Digestive and Kidney Diseases , National Institutes of Health , Bldg. 8A, Rm. B1A-19, NIH, NIDDK, LBC , Bethesda , Maryland 20892-0810 , USA . Email: kennethj@niddk.nih.gov ; ; Tel: +301 496 9024., Jacobson KA; Molecular Recognition Section , Laboratory of Bioorganic Chemistry , National Institute of Diabetes and Digestive and Kidney Diseases , National Institutes of Health , Bldg. 8A, Rm. B1A-19, NIH, NIDDK, LBC , Bethesda , Maryland 20892-0810 , USA . Email: kennethj@niddk.nih.gov ; ; Tel: +301 496 9024.
Publikováno v:
MedChemComm [Medchemcomm] 2018 Oct 18; Vol. 9 (11), pp. 1920-1932. Date of Electronic Publication: 2018 Oct 18 (Print Publication: 2018).