Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sami Piirainen"'
Autor:
Natalia Kulesskaya, Ekaterina Mugantseva, Rimante Minkeviciene, Natalia Acosta, Ari Rouhiainen, Juha Kuja-Panula, Mikhail Kislin, Sami Piirainen, Mikhail Paveliev, Heikki Rauvala
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Protamine is an arginine-rich peptide that replaces histones in the DNA-protein complex during spermatogenesis. Protamine is clinically used in cardiopulmonary bypass surgery to neutralize the effects of heparin that is required during the treatment.
Externí odkaz:
https://doaj.org/article/88989e4754cf49b2830a70c537929320
Autor:
Sami Piirainen, Julie C. Savage, Kanchan Bisht, Marie-Ève Tremblay, Keerthana Chithanathan, Maria Piirsalu, Li Tian
Microglial activation has been regarded mainly as an exacerbator of stress response, a common symptom in psychiatric disorders. This study aimed to determine whether microglia contribute to adaptive response of the brain and behavior toward stress us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af3350c9ffbbc067067ad9037ce2854
http://hdl.handle.net/10138/345306
http://hdl.handle.net/10138/345306
Autor:
Allan V. Kalueff, Gary E. Landreth, Sami Piirainen, Andrew Youssef, Li Tian, Cai Song, Tarja Malm
Publikováno v:
Neuroscience and biobehavioral reviews. 77
Chronic psychosocial stress is increasingly recognized as a risk factor for late-onset Alzheimer's disease (LOAD) and associated cognitive deficits. Chronic stress also primes microglia and induces inflammatory responses in the adult brain, thereby c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890cdfc122ece89042e6d1463090df02
https://pubmed.ncbi.nlm.nih.gov/28185874
https://pubmed.ncbi.nlm.nih.gov/28185874
Substantial evidence indicates involvement of microglia/macrophages in chronic neuropathic pain. However, the temporal-spatial features of microglial/macrophage activation and their pain-bound roles remain elusive. Here, we evaluated microglia/macrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324a7d4e92d927e8371e002491064c9e
http://hdl.handle.net/10138/228574
http://hdl.handle.net/10138/228574
Publikováno v:
Neurology, Psychiatry and Brain Research. 29:19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b68b14196349f37d24268ff2bfe77481
https://doi.org/10.1016/j.npbr.2018.01.095
https://doi.org/10.1016/j.npbr.2018.01.095
Publikováno v:
Journal of Neuroinflammation
Background: Social deficit is one of the core symptoms of neuropsychiatric diseases, in which immune genes play an important role. Although a few immune genes have been shown to regulate social and emotional behaviors, how immune gene network(s) may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204cb03fcdbbe2f79ac110734e542051
http://hdl.handle.net/10138/162221
http://hdl.handle.net/10138/162221
Autor:
Sami Piirainen, Li Tian
Publikováno v:
Brain, Behavior, and Immunity. 49:e46
Microglia play a pivotal role in the brain development and plasticity through synaptic pruning. Morphological change of microglia reflects a key feature in this process and has been used to define microglial activation. Most studies have applied two-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eb8132b26f99e7445b8aada26a2763e
https://doi.org/10.1016/j.bbi.2015.06.172
https://doi.org/10.1016/j.bbi.2015.06.172
Publikováno v:
In Neurology, Psychiatry and Brain Research March 2016 22(1):23-23