Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sami Mamand"'
Autor:
Golam T Saffi, Evan Tang, Sami Mamand, Subothan Inpanathan, Aaron Fountain, Leonardo Salmena, Roberto J Botelho
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0259313 (2021)
Lysosomes are terminal, degradative organelles of the endosomal pathway that undergo repeated fusion-fission cycles with themselves, endosomes, phagosomes, and autophagosomes. Lysosome number and size depends on balanced fusion and fission rates. Thu
Externí odkaz:
https://doaj.org/article/2e13202baa35471ea147821ba54376ff
Autor:
Katherine Wickenden, Nadia Nawaz, Sami Mamand, Deevia Kotecha, Amy L. Wilson, Simon D. Wagner, Matthew J. Ahearne
Publikováno v:
Diagnostic Pathology, Vol 13, Iss 1, Pp 1-10 (2018)
Abstract Background Abnormally sustained immune reactions drive B-cell proliferation in some cases of marginal zone lymphoma but the CD4+ T-cell subsets, which are likely to contribute to the B-cell responses in the tumour microenvironment, are not w
Externí odkaz:
https://doaj.org/article/b96e0859e0794a68b23e4ff121263edd
Autor:
Rebecca L Allchin, Michael E Kelly, Sami Mamand, Anthony G Doran, Thomas Keane, Matthew J Ahearne, Simon D Wagner
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215765 (2019)
Recent analyses of the genetics of peripheral T-cell lymphoma (PTCL) have shown that a large proportion of cases are derived from normal follicular helper (Tfh) T-cells. The sanroque mouse strain bears a mutation that increases Tfh cell number and he
Externí odkaz:
https://doaj.org/article/6fb98bd0807a4371ababb29800aa0c00
Autor:
Maxime Boutry, Laura F. DiGiovanni, Nicholas Demers, Aaron Fountain, Sami Mamand, Roberto J. Botelho, Peter K. Kim
Formation and fission of tubules from lysosomal organelles, such as autolysosomes, endolysosomes or phagolysosomes, are required for lysosome reformation. However, the mechanisms governing these processes in the different forms of lysosomal organelle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99d1a136658dfbde2c951c5b9dace255
https://doi.org/10.1101/2023.03.24.534147
https://doi.org/10.1101/2023.03.24.534147
Autor:
Roberto Botelho, Leonardo Salmena, Aaron Fountain, Subothan Inpanathan, Sami Mamand, Evan Tang, Golam T. Saffi
Lysosomes are terminal, degradative organelles of the endosomal pathway that undergo repeated fusion-fission cycles with themselves, endosomes, phagosomes, and autophagosomes. Lysosome number and size depends on balanced fusion and fission rates. Thu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fa1e784ebc1f846dcd639027bdf34bd
https://doi.org/10.32920/21982916
https://doi.org/10.32920/21982916
Autor:
Paul Fields, Barbara Ottolini, Christopher S. Trethewey, Nadia Nawaz, Matthew J. Ahearne, Simon D. Wagner, Rebecca L. Allchin, Sami Mamand, Richard Dillon
Publikováno v:
Blood Adv
The mutational landscape of peripheral T-cell lymphoma (PTCL) is being revealed through sequencing of lymph node samples, but there has been little work on the mutational load that is present in cell-free DNA (cfDNA) from plasma. We report targeted s
Autor:
Roberto J. Botelho, Sami Mamand, Leonardo Salmena, Aaron Fountain, Subothan Inpanathan, Golam T. Saffi, Evan Tang
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0259313 (2021)
PLoS ONE
PLoS ONE
Lysosomes are terminal, degradative organelles of the endosomal pathway that undergo repeated fusion-fission cycles with themselves, endosomes, phagosomes, and autophagosomes. Lysosome number and size depends on balanced fusion and fission rates. Thu
Publikováno v:
Journal of Cellular and Molecular Medicine
The IKK‐related kinases, IKKε and TBK1, have essential roles in innate immunity in part through modifying MYD88 signalling from the Toll‐like receptors to regulate NF‐κB signalling. We investigated the expression and function of IKKε and TBK
Key Points ITK inhibitors perturb functional changes due to polarizing culture conditions in normal human tonsil CD4+ T cells. Primary human PTCL cells alter their functional properties in culture and ITK inhibitors modify these changes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d03179217a2ac6122746eb39dde7d8e
https://europepmc.org/articles/PMC6418494/
https://europepmc.org/articles/PMC6418494/
Autor:
Deevia Kotecha, Sami Mamand, Simon D. Wagner, Nadia Nawaz, Matthew J. Ahearne, Amy L. Wilson, Katherine Wickenden
Publikováno v:
Diagnostic Pathology, Vol 13, Iss 1, Pp 1-10 (2018)
Diagnostic Pathology
Diagnostic Pathology
Background Abnormally sustained immune reactions drive B-cell proliferation in some cases of marginal zone lymphoma but the CD4+ T-cell subsets, which are likely to contribute to the B-cell responses in the tumour microenvironment, are not well chara