Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sami I. Somo"'
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
The current standard treatment for Type 1 diabetes is the administration of exogenous insulin to manage blood glucose levels. Cellular therapies are in development to address this dependency and allow patients to produce their own insulin. Studies ha
Externí odkaz:
https://doaj.org/article/e306afd6c8ab4543920a25ff4d9bd80c
Autor:
Ranjit John, Manreet K. Kanwar, Joseph C. Cleveland, Nir Uriel, Yoshifumi Naka, Christopher Salerno, Douglas Horstmanshof, Shelley A. Hall, Jennifer A. Cowger, Gerald Heatley, Sami I. Somo, Mandeep R. Mehra
Publikováno v:
The Journal of thoracic and cardiovascular surgery.
Correction of valvular disease is often undertaken during left ventricular assist device (LVAD) implantation with uncertain benefit. We analyzed clinical outcomes with HeartMate 3 (HM3; Abbott) LVAD implantation in those with various concurrent valve
Autor:
Walter P. Dembitsky, D. Crandall, Joseph C. Cleveland, Paolo C. Colombo, Dong Chen, Keerthy Narisetty, David E. Lanfear, Daniel J. Goldstein, Samer S. Najjar, Aditya Bansal, Jean M. Connors, Sami I. Somo, James W. Long, Eric Adler, Mandeep R. Mehra, Nir Uriel, Arvind Bhimaraj, John M. Stulak
Publikováno v:
The Journal of Heart and Lung Transplantation. 38:806-816
Increased shear stress conferred upon the circulation by continuous-flow pumps is associated with hemocompatibility-related adverse events, principally bleeding within the gastrointestinal system, and linked to the degradation of high-molecular-weigh
Autor:
Christopher T. Salerno, D. Crandall, Claudius Mahr, Francis X Downey, Ulrich P. Jorde, Michael M. Givertz, Masahiro Ono, Anelechi C. Anyanwu, Paolo C. Colombo, Douglas A. Horstmanshof, Joseph C. Cleveland, Daniel J. Goldstein, Ia Topuria, Jerry D. Estep, Mandeep R. Mehra, Nir Uriel, Sami I. Somo, Jennifer A Cowger, Robert Hooker, Eric Skipper, Gabriel Sayer
Publikováno v:
Circulation. 139:155-168
Background: The MOMENTUM 3 study (Multicenter Study of MagLev Technology in Patients Undergoing Mechanical Circulatory Support Therapy With HeartMate 3) has demonstrated that the HeartMate 3 (HM3) pump is associated with reduced strokes compared with
Publikováno v:
Frontiers in Chemistry
Frontiers in Chemistry, Vol 8 (2020)
Frontiers in Chemistry, Vol 8 (2020)
The current standard treatment for Type 1 diabetes is the administration of exogenous insulin to manage blood glucose levels. Cellular therapies are in development to address this dependency and allow patients to produce their own insulin. Studies ha
Autor:
Laura J. Blue, Joseph C. Cleveland, Ranjit John, Vinay Thohan, Poornima Sood, Chetan B. Patel, Sami I. Somo, John W. Entwistle, Mandeep R. Mehra, Nir Uriel, Daniel J. Goldstein, Stephen H. Bailey, B. Cagliostro, Xiaolu Su
Publikováno v:
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 39(8)
In a randomized controlled trial (MOMENTUM 3), the HeartMate 3 (HM3) fully magnetically levitated centrifugal-flow left ventricular assist device (LVAD) demonstrated superiority over the HeartMate II (HMII) axial-flow LVAD. These findings were driven
Autor:
Frank J. Brooks, Weimin Zhou, Eric M. Brey, Mark A. Anastasio, Sami I. Somo, Sergey Komarov, Jacob Brown
Publikováno v:
Ann Biomed Eng
Imaging soft biomaterials in vivo is a significant challenge, as most conventional techniques are limited by biomaterial contrast, penetration depth, or spatial resolution. Exogeneous contrast agents used to increase contrast may also alter material
Autor:
Huifeng Guan, Emmanuel C. Opara, Sami I. Somo, Veronica Ibarra, Alyssa A. Appel, Jeffery C. Larson, John P. McQuilling, Alfred Garson, Eric M. Brey, Mark A. Anastasio, Zhong Zhong
Publikováno v:
Tissue Engineering Part C: Methods. 22:1038-1048
Transplantation of functional islets encapsulated in stable biomaterials has the potential to cure Type I diabetes. However, the success of these materials requires the ability to quantitatively evaluate their stability. Imaging techniques that enabl
Publikováno v:
BioResearch Open Access
BioResearch Open Access, Vol 5, Iss 1, Pp 342-355 (2016)
BioResearch Open Access, Vol 5, Iss 1, Pp 342-355 (2016)
Stable and extensive blood vessel networks are required for cell function and survival in engineered tissues. A number of different strategies are currently being investigated to enhance biomaterial vascularization with screening primarily through ex
Publikováno v:
Tissue Engineering Part B: Reviews. 22:34-46
Human trials have demonstrated the feasibility of alginate-encapsulated islet cells for the treatment of type 1 diabetes. Encapsulated islets can be protected from the host's immune system and remain viable and functional following transplantation. H