Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Sami Blom"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract High-grade extrauterine serous carcinoma (HGSC) is an aggressive tumor with high rates of recurrence, frequent chemotherapy resistance, and overall 5-year survival of less than 50%. Beyond determining and confirming the diagnosis itself, pat
Externí odkaz:
https://doaj.org/article/dec4332aac824453a0d7dbb9e180088a
Autor:
Nelli Sjöblom, Sonja Boyd, Anniina Manninen, Anna Knuuttila, Sami Blom, Martti Färkkilä, Johanna Arola
Publikováno v:
Diagnostic Pathology, Vol 16, Iss 1, Pp 1-12 (2021)
Abstract Background The objective was to build a novel method for automated image analysis to locate and quantify the number of cytokeratin 7 (K7)-positive hepatocytes reflecting cholestasis by applying deep learning neural networks (AI model) in a c
Externí odkaz:
https://doaj.org/article/396e6f366dfa4174966f5054eae9f2dc
Autor:
Kevin Sandeman, Sami Blom, Ville Koponen, Anniina Manninen, Juuso Juhila, Antti Rannikko, Tuomas Ropponen, Tuomas Mirtti
Publikováno v:
Diagnostics, Vol 12, Iss 5, p 1031 (2022)
An artificial intelligence (AI) algorithm for prostate cancer detection and grading was developed for clinical diagnostics on biopsies. The study cohort included 4221 scanned slides from 872 biopsy sessions at the HUS Helsinki University Hospital dur
Externí odkaz:
https://doaj.org/article/b108e6a8540a4c88bc954b420bbdf8e0
Autor:
Ashwini S. Nagaraj, Jenni Lahtela, Annabrita Hemmes, Teijo Pellinen, Sami Blom, Jennifer R. Devlin, Kaisa Salmenkivi, Olli Kallioniemi, Mikko I. Mäyränpää, Katja Närhi, Emmy W. Verschuren
Publikováno v:
Cell Reports, Vol 18, Iss 3, Pp 673-684 (2017)
Lung cancers exhibit pronounced functional heterogeneity, confounding precision medicine. We studied how the cell of origin contributes to phenotypic heterogeneity following conditional expression of KrasG12D and loss of Lkb1 (Kras;Lkb1). Using proge
Externí odkaz:
https://doaj.org/article/4865c03d589649f090200e998d1e2cd4
Autor:
Nelli Sjöblom, Sonja Boyd, Anniina Manninen, Sami Blom, Anna Knuuttila, Martti Färkkilä, Johanna Arola
Publikováno v:
Hepatology Research. 53:322-333
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease that obstructs the bile ducts and causes liver cirrhosis and cholangiocarcinoma. Efficient surrogate markers are required to measure disease progression. The cytokeratin 7 (K
Autor:
Laura Mairinoja, Hanna Heikelä, Sami Blom, Darshan Kumar, Anna Knuuttila, Sonja Boyd, Nelli Sjöblom, Eva-Maria Birkman, Petteri Rinne, Pekka Ruusuvuori, Leena Strauss, Matti Poutanen
Publikováno v:
The American Journal of Pathology.
Autor:
Tuomas Mirtti, Antti Rannikko, Olli Kallioniemi, Stig Nordling, Anu Kenttämies, Juho Eineluoto, Katja Välimäki, Annabrita Hemmes, Riku Turkki, Sami Blom, Kevin Sandeman, Teijo Pellinen
Some clinically significant prostate cancers are missed by MRI. We asked whether the tumor stroma in surgically treated localized prostate cancer lesions positive or negative with MRI are different in their cellular and molecular properties, and whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80a95e40ca19584e84700f27fafab86
https://doi.org/10.1158/2767-9764.c.6550682
https://doi.org/10.1158/2767-9764.c.6550682
Autor:
Tuomas Mirtti, Antti Rannikko, Olli Kallioniemi, Stig Nordling, Anu Kenttämies, Juho Eineluoto, Katja Välimäki, Annabrita Hemmes, Riku Turkki, Sami Blom, Kevin Sandeman, Teijo Pellinen
Supplementary Tables S1-S7. Supplementary Figures S1-S4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aeee45363f24aa0999c1dc8acd78302
https://doi.org/10.1158/2767-9764.22544537
https://doi.org/10.1158/2767-9764.22544537
Autor:
Teijo Pellinen, Kevin Sandeman, Sami Blom, Riku Turkki, Annabrita Hemmes, Katja Välimäki, Juho Eineluoto, Anu Kenttämies, Stig Nordling, Olli Kallioniemi, Antti Rannikko, Tuomas Mirtti
Publikováno v:
Cancer Research Communications. 2:172-181
Some clinically significant prostate cancers are missed by MRI. We asked whether the tumor stroma in surgically treated localized prostate cancer lesions positive or negative with MRI are different in their cellular and molecular properties, and whet
Autor:
Tiina, Vesterinen, Jenni, Säilä, Sami, Blom, Mirkka, Pennanen, Helena, Leijon, Johanna, Arola
Publikováno v:
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 130(1)
The Ki-67 proliferation index (PI) is a prognostic factor in neuroendocrine tumors (NETs) and defines tumor grade. Analysis of Ki-67 PI requires calculation of Ki-67-positive and Ki-67-negative tumor cells, which is highly subjective. To overcome thi