Výsledky vyhledávání - "Sami, Elmoufti"

Akademický článek

Effectiveness and safety of certolizumab pegol in rheumatoid arthritis patients in Canadian practice: 2-year results from the observational FαsT-CAN study

Autor: Louis Bessette, Boulos Haraoui, Andrew Chow, Isabelle Fortin, Sanjay Dixit, Majed Khraishi, Derek Haaland, Sami Elmoufti, Fabienne Staelens, Irina Bogatyreva, Jerry Syrotuik, Saeed Shaikh

Publikováno v: Therapeutic Advances in Musculoskeletal Disease, Vol 11 (2019)

Background: The aim of this study was to assess the real-world effectiveness and safety of certolizumab pegol (CZP) in rheumatoid arthritis (RA) patients, and the impact on patients’ productivity, pain, and fatigue, in Canadian practice. Methods: F

Externí odkaz: https://doaj.org/article/e952626a7a0747799c50c8b50f3dc5d5

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Tolerability and efficacy of adjunctive brivaracetam in adults with focal seizures by concomitant antiseizure medication use: Pooled results from three phase 3 trials

Autor: Philippe Ryvlin, Svetlana Dimova, Sami Elmoufti, Florin Floricel, Cédric Laloyaux, Xavier Nondonfaz, Victor Biton

Publikováno v: Ryvlin, P, Dimova, S, Elmoufti, S, Floricel, F, Laloyaux, C, Nondonfaz, X & Biton, V 2022, ' Tolerability and efficacy of adjunctive brivaracetam in adults with focal seizures by concomitant antiseizure medication use : Pooled results from three phase 3 trials ', Epilepsia, vol. 63, no. 8, pp. 2024-2036 . https://doi.org/10.1111/epi.17304

Objective: This study was undertaken to evaluate safety/tolerability and efficacy of adjunctive brivaracetam (BRV) in patients on one or two concomitant antiseizure medications (ASMs) and in patients on one specific concomitant ASM. Methods: Post hoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe708e073149db2d42b0072ca0a277ba
https://pubmed.ncbi.nlm.nih.gov/35582748

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Retention, efficacy, tolerability, and quality of life during long-term adjunctive brivaracetam treatment by number of lifetime antiseizure medications: A post hoc analysis of phase 3 trials in adults with focal seizures

Autor: Christian, Brandt, Svetlana, Dimova, Sami, Elmoufti, Cédric, Laloyaux, Xavier, Nondonfaz, Pavel, Klein

Publikováno v: Epilepsy & Behavior. 138:108967

To evaluate long-term retention, reasons for discontinuation, efficacy, tolerability, and health-related quality of life (HRQOL) during adjunctive brivaracetam (BRV) treatment in adults with focal seizures by number of lifetime antiseizure medication

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca98eca4f9abe613da693da58eb786db
https://doi.org/10.1016/j.yebeh.2022.108967

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Effect of Number of Previous Antiseizure Medications on Efficacy and Tolerability of Adjunctive Brivaracetam for Uncontrolled Focal Seizures: Post Hoc Analysis

Autor: Sang-Ahm Lee, Cédric Laloyaux, Boeun Hur, Sung Eun Kim, Sang-Kun Lee, Sami Elmoufti, Kyoung Heo

Publikováno v: Advances in therapy. 38(7)

The aim was to evaluate the efficacy and tolerability of adjunctive brivaracetam (BRV) in adults with severely drug-resistant focal seizures versus adults with less drug-resistant disease. Data were pooled from patients with focal seizures on 1–2 c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ba397b0087eadf6e0f961d2c3473cc
https://pubmed.ncbi.nlm.nih.gov/34155568

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Towards realizing the vision of precision medicine: AI based prediction of clinical drug response

Autor: Johann de Jong, Matthew Page, Martin Armstrong, Holger Fröhlich, Sami Elmoufti, Cynthia Dilley, Ioana Cutcutache

Publikováno v: Brain

See Chen et al. (doi:10.1093/brain/awab199) for a scientific commentary on this article. De Jong et al. present a retrospectively validated machine learning model linking drug mechanism of action and patients' genetic/clinical/demographic background

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435b8495e15e3ae460b2687b8c67feb5
https://publica.fraunhofer.de/handle/publica/266647

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Long-term safety and efficacy of brivaracetam in adults with focal seizures: Results from an open-label, multinational, follow-up trial

Autor: Stephen Yates, Anne-Liv Schulz, Sami Elmoufti, Cédric Laloyaux, Toufic Fakhoury, Stephan Arnold

Publikováno v: Epilepsy research. 166

Background This long-term follow-up (LTFU) trial was conducted to evaluate the long-term safety and tolerability of brivaracetam (BRV) at individualized doses (maximum of 200 mg/day) in patients with focal seizures. The secondary objective was to eva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe79aaa2140e585a163a16dad11b3d5
https://pubmed.ncbi.nlm.nih.gov/32731118

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Effect of lifetime antiepileptic drug treatment history on efficacy and tolerability of adjunctive brivaracetam in adults with focal seizures: Post-hoc analysis of a randomized, placebo-controlled trial

Autor: Pavel Klein, Sami Elmoufti, Xavier Nondonfaz, Richard S. McLachlan, Kathy Foris, Svetlana Dimova, Christian Brandt

Publikováno v: Epilepsy research. 167

Objective To evaluate the efficacy and tolerability of adjunctive brivaracetam (BRV) in adults with focal seizures by the number of lifetime (previous and concomitant) antiepileptic drugs (AEDs). Methods Post-hoc analysis of data from N01358 (NCT0126

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b1f116881b6a295e2631684dc7e7d1
https://pubmed.ncbi.nlm.nih.gov/32717713

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