Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Samhita Rao"'
Autor:
Yang Li, Nato Teteloshvili, Shulian Tan, Samhita Rao, Arnold Han, Yong-Guang Yang, Rémi J. Creusot
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Thymic selection constitutes the first checkpoint in T-cell development to purge autoreactive T cells. Most of our understanding of this process comes from animal models because of the challenges of studying thymopoiesis and how T cell receptor (TCR)
Externí odkaz:
https://doaj.org/article/938c9ed0d6074e4799ab4abc2719510e
Autor:
Doina Atanasiu, Tina M. Cairns, J. Charles Whitbeck, Wan Ting Saw, Samhita Rao, Roselyn J. Eisenberg, Gary H. Cohen
Publikováno v:
mBio, Vol 4, Iss 2 (2013)
ABSTRACT Herpesvirus entry requires the viral glycoprotein triad of gB and gH/gL to carry out fusion between the virion envelope and a cellular membrane in order to release the nucleocapsid into the target cell. Herpes simplex virus (HSV) also requir
Externí odkaz:
https://doaj.org/article/11718a2a284845c5b08b78366a1df839
Autor:
Samhita Rao, Aleksandar Obradovic, Karim Gharib, Adam Kornberg, Theo Botella, Christine Moon, Ali Ghasemzadeh, Sijie Lin, Izabela Krupska, Erin Bush, Alan J. Korman, Kelley S. Yan, Charles G. Drake, Andrea Califano, Arnold Han
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9503e395fad4233f5c912cbc3e6b537
https://doi.org/10.2139/ssrn.4144960
https://doi.org/10.2139/ssrn.4144960
Autor:
Michael M. Givertz, Mohsen Khosravi-Maharlooei, Sijie Lin, Megan Sykes, Maryjane Farr, Yoshifumi Naka, Marlena V. Habal, Charles C. Marboe, Siu-hong Ho, Arnold Han, Koji Takeda, Aleksandar Obradovic, Poulomi Roy, Sarah See, Susan Restaino, Emmanuel Zorn, Linda J. Addonizio, April M.I Miller, Donna M. Mancini, Shihab Ronzon, Samhita Rao, Joren C. Madsen
Publikováno v:
Am J Transplant
T cells are implicated in the pathogenesis of cardiac allograft vasculopathy (CAV), yet their clonality, specificity, and function are incompletely defined. Here we used T cell receptor β chain (TCRB) sequencing to study the T cell repertoire in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7e15d32a4fcbfb2482379011e7877e
https://europepmc.org/articles/PMC8672660/
https://europepmc.org/articles/PMC8672660/
Autor:
Peder Lund, Samhita Rao, Malek Faham, Joshua E. Elias, Niclas Olsson, Debra K. Czerwinski, Lisa E. Wagar, Henning Stehr, Chih Long Liu, Michael S. Khodadoust, Caleb D. Marceau, Binbin Chen, Keith Rawson, Kavya Swaminathan, Lichao Zhang, Victoria Carlton, Ronald Levy, Martin Moorhead, Ole Audun Werner Haabeth, Ash A. Alizadeh, Jan E. Carette, Holbrook E Kohrt, Michael R. Green, Aaron M. Newman, David F. Steiner, Mark M. Davis
Publikováno v:
Nature
Nature, vol 543, iss 7647
Nature, vol 543, iss 7647
Cancer somatic mutations can generate neoantigens that distinguish malignant from normal cells. However, the personalized identification and validation of neoantigens remains a major challenge. Here we discover neoantigens in human mantle-cell lympho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aff82c63e959264603cb107aff7a617
https://doi.org/10.1038/nature21433
https://doi.org/10.1038/nature21433
Publikováno v:
International review of cell and molecular biology. 342
Cancer immunotherapy is based on the ability of the immune system to recognize tumors as foreign tissue. The idea of cancer immunosurveillance was first conceived over a century ago but remained controversial through much of the 20th century. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e4027f5cc573b29e5d0632a5774e4e6
https://pubmed.ncbi.nlm.nih.gov/30635090
https://pubmed.ncbi.nlm.nih.gov/30635090
Publikováno v:
International Review of Cell and Molecular Biology ISBN: 9780128153819
Cancer immunotherapy is based on the ability of the immune system to recognize tumors as foreign tissue. The idea of cancer immunosurveillance was first conceived over a century ago but remained controversial through much of the 20th century. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21756aa016e7e48896e34e18fceaf670
https://doi.org/10.1016/bs.ircmb.2018.08.001
https://doi.org/10.1016/bs.ircmb.2018.08.001
Autor:
Maryjane Farr, Samhita Rao, Linda J. Addonizio, Marlena V. Habal, Joren C. Madsen, Sarah B. See, P. Roy, Emmanuel Zorn, Susan Restaino, Arnold Han, A. Myung, Charles C. Marboe, R.R. Shihab, Michael M. Givertz
Publikováno v:
The Journal of Heart and Lung Transplantation. 38:S157-S158
Purpose T-cells are implicated in the pathogenesis of cardiac allograft vasculopathy (CAV), yet their clonal composition and function are incompletely defined. We examined the T-cell receptor β (TCRβ) repertoire from explanted grafts with CAV and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2d98a619201bf7b6b67f521135d9c60
https://doi.org/10.1016/j.healun.2019.01.376
https://doi.org/10.1016/j.healun.2019.01.376
Autor:
Samhita Rao, Adam Kornberg, Sijie Lin, Karim Gharib, Lahari Koganti, Javier Alejandro Garcia-Vilas Garcia, Kazuya Masuda, Arnold Han
Publikováno v:
The Journal of Immunology. 202:195.3-195.3
Checkpoint blockade immunotherapy has shown great success in certain types of cancers, but are ineffective in most cancers. We do not understand why these therapies fail. Here, we seek to better understand functional changes in T cells in responsive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fab16de0e5c411649139911edc4d9f3
https://doi.org/10.4049/jimmunol.202.supp.195.3
https://doi.org/10.4049/jimmunol.202.supp.195.3
Autor:
Niclas Olsson, Michael Khodadoust, Lisa Wagar, Kavya Swaminathan, Ole Audun Werner Haabeth, Binbin Chen, Keith Rawson, Chih Long Liu, David Steiner, Peder J. Lund, Samhita Rao, Lichao Zhang, Caleb Marceau, Henning Stehr, Aaron M. Newman, Debra K. Czerwinski, Victoria Carlton, Martin Moorhead, Malek Faham, Holbrook E. Kohrt, Jan Carette, Michael R. Green, Mark M. Davis, Ron Levy, Ash A. Alizadeh, Joshua E. Elias
Publikováno v:
The Journal of Immunology. 198:196.9-196.9
Presentation of novel antigenic peptides (neoantigens) that distinguish malignant from normal cells by major histocompatibility complexes (MHC) can serve as potent substrates for specific anti-tumor immune responses. We sought to identify mantle cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31176b0804c09345be6c5613d655e5da
https://doi.org/10.4049/jimmunol.198.supp.196.9
https://doi.org/10.4049/jimmunol.198.supp.196.9