Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Samhan Alsolami"'
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111122- (2024)
Summary: Pluripotent-stem-cell-derived blastocyst-like structures (blastoids) offer insights into early human embryogenesis (5–10 days post-fertilization). The similarity between blastoids and human blastocysts remains uncertain. To investigate, we
Externí odkaz:
https://doaj.org/article/78cabb81236f47669f92b6e6c6dd5b4c
Autor:
Yong Fan, Zheying Min, Samhan Alsolami, Zhenglai Ma, E. Zhang, Wei Chen, Ke Zhong, Wendi Pei, Xiangjin Kang, Puyao Zhang, Yongliang Wang, Yingying Zhang, Linfeng Zhan, Haiying Zhu, Chenrui An, Rong Li, Jie Qiao, Tao Tan, Mo Li, Yang Yu
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract Human blastocysts are comprised of the first three cell lineages of the embryo: trophectoderm, epiblast and primitive endoderm, all of which are essential for early development and organ formation. However, due to ethical concerns and restri
Externí odkaz:
https://doaj.org/article/0b45748d96074452b9a865352f6661f1
Autor:
Chongwei Bi, Lin Wang, Yong Fan, Baolei Yuan, Samhan Alsolami, Yingzi Zhang, Pu-Yao Zhang, Yanyi Huang, Yang Yu, Juan Carlos Izpisua Belmonte, Mo Li
Publikováno v:
Nucleic Acids Research. 51:3793-3805
Maternal mitochondria are the sole source of mtDNA for every cell of the offspring. Heteroplasmic mtDNA mutations inherited from the oocyte are a common cause of metabolic diseases and associated with late-onset diseases. However, the origin and dyna
Autor:
Chongwei Bi, Lin Wang, Yong Fan, Baolei Yuan, Gerardo Ramos-Mandujano, Yingzi Zhang, Samhan Alsolami, Xuan Zhou, Jincheng Wang, Yanjiao Shao, Pradeep Reddy, Pu-Yao Zhang, Yanyi Huang, Yang Yu, Juan Carlos Izpisua Belmonte, Mo Li
Publikováno v:
Nucleic Acids Research. 51:e48-e48
The ontogeny and dynamics of mtDNA heteroplasmy remain unclear due to limitations of current mtDNA sequencing methods. We developed individual Mitochondrial Genome sequencing (iMiGseq) of full-length mtDNA for ultra-sensitive variant detection, compl