Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Samer R. Eid"'
Autor:
Samer R. Eid
Publikováno v:
Current Topics in Medicinal Chemistry. 11:2118-2130
Following the cloning and characterization of the transient receptor potential vanilloid 1 (TRPV1), a growing body of research has identified the important role of TRPV1 and related channels in diverse physiological functions including temperature tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac66729687666c2679c4c6ac1a8cede
https://doi.org/10.2174/156802611796904898
https://doi.org/10.2174/156802611796904898
Publikováno v:
Nature Reviews Drug Discovery. 6:357-372
The clinical use of TRPV1 (transient receptor potential vanilloid subfamily, member 1; also known as VR1) antagonists is based on the concept that endogenous agonists acting on TRPV1 might provide a major contribution to certain pain conditions. Inde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ee5611b1f77f6152ff4bfd8eef0977
https://doi.org/10.1038/nrd2280
https://doi.org/10.1038/nrd2280
Autor:
Lindsey J. Macpherson, Sun Wook Hwang, Bernhard H. Geierstanger, Samer R. Eid, Veena Viswanath, Michael Bandell, Ardem Patapoutian
Publikováno v:
Current Biology. 15:929-934
SummaryGarlic’s pungent flavor has made it a popular ingredient in cuisines around the world and throughout history. Garlic’s health benefits have been elevated from folklore to clinical study [1–5]. Although there is some controversy as to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8039d77e6df750ba0598583df0675bd7
https://doi.org/10.1016/j.cub.2005.04.018
https://doi.org/10.1016/j.cub.2005.04.018
Autor:
André W. Brändli, Samer R. Eid
Publikováno v:
Differentiation. 68:115-125
The osmoregulatory function of the pronephric kidney, the first excretory organ of the vertebrate embryo, is essential for embryonic survival. The transport systems engaged in pronephric osmotic regulation are however poorly understood. The Na,K-ATPa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0200321b3f219498aa6940c5d39d54
https://doi.org/10.1046/j.1432-0436.2001.680205.x
https://doi.org/10.1046/j.1432-0436.2001.680205.x
Publikováno v:
The International journal of developmental biology. 46(1)
Plasma membrane proteins of the solute carrier family 5 (SLC5) are responsible for sodium-coupled uptake of ions, sugars and nutrients in the vertebrate body. Mutations in SLC5 genes are the cause of several inherited human disorders. We have recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c56d60635d8d80e7bfa397de757cb1e2
https://pubmed.ncbi.nlm.nih.gov/11902681
https://pubmed.ncbi.nlm.nih.gov/11902681
Publikováno v:
Nature Reviews Drug Discovery. 6:500-500
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c16c51ecd87ff9223643289f104fd4bd
https://doi.org/10.1038/nrd2337
https://doi.org/10.1038/nrd2337
Autor:
Gina M. Story, Samer R. Eid, Ardem Patapoutian, Veena Viswanath, Taryn J. Earley, Michael Bandell, Sun Wook Hwang, Matt Petrus
Publikováno v:
Neuron. (6):849-857
Six members of the mammalian transient receptor potential (TRP) ion channels respond to varied temperature thresholds. The natural compounds capsaicin and menthol activate noxious heat-sensitive TRPV1 and cold-sensitive TRPM8, respectively. The burni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8800346bd9733ee1a6cc8cf36d243364
Autor:
Samer R. Eid, Timothy Jegla, Taryn J. Earley, Andrea M. Peier, Anne C. Hergarden, Alison J. Reeve, Stuart Bevan, David Andersson, Peter McIntyre, Gina M. Story, Ardem Patapoutian, Sun Wook Hwang, Johannes Mosbacher, Todd R. Hricik
Publikováno v:
Cell. (6):819-829
Mammals detect temperature with specialized neurons in the peripheral nervous system. Four TRPV-class channels have been implicated in sensing heat, and one TRPM-class channel in sensing cold. The combined range of temperatures that activate these ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de512d65f586f8746913d57e9efe6831