Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Samer Hattar"'
Autor:
Cheng Qian, Ying Xin, Cheng Qi, Hui Wang, Bryan C. Dong, Donald J. Zack, Seth Blackshaw, Samer Hattar, Feng-Quan Zhou, Jiang Qian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Previous studies of neuronal survival have primarily focused on identifying intrinsic mechanisms controlling the process. This study explored how intercellular communication contributes to retinal ganglion cell (RGC) survival following optic
Externí odkaz:
https://doaj.org/article/b1cda4bead69404db2565077129f3d56
Autor:
Robert J. Lucas, Annette E. Allen, George C. Brainard, Timothy M. Brown, Robert T. Dauchy, Altug Didikoglu, Michael Tri H. Do, Brianna N. Gaskill, Samer Hattar, Penny Hawkins, Roelof A. Hut, Richard J. McDowell, Randy J. Nelson, Jan-Bas Prins, Tiffany M. Schmidt, Joseph S. Takahashi, Vandana Verma, Vootele Voikar, Sara Wells, Stuart N. Peirson
Publikováno v:
PLoS Biology, Vol 22, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/9ed1e20c926a458294fbee6cdaba0d03
Autor:
Raniki Kumari, Raluca Pascalau, Hui Wang, Sheetal Bajpayi, Maria Yurgel, Kwaku Quansah, Samer Hattar, Emmanouil Tampakakis, Rejji Kuruvilla
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113674- (2024)
Summary: Neuropeptide Y (NPY) is best known for its effects in the brain as an orexigenic and anxiolytic agent and in reducing energy expenditure. NPY is also co-expressed with norepinephrine (NE) in sympathetic neurons. Although NPY is generally con
Externí odkaz:
https://doaj.org/article/c38856c2b284460a8201f052e4c441ab
Autor:
John L Hunyara, K M Daly, Katherine Torres, Maria E Yurgel, Ruchi Komal, Samer Hattar, Alex L Kolodkin
Publikováno v:
PLoS Biology, Vol 21, Iss 12, p e3002412 (2023)
Visual system function depends upon the elaboration of precise connections between retinal ganglion cell (RGC) axons and their central targets in the brain. Though some progress has been made in defining the molecules that regulate RGC connectivity r
Externí odkaz:
https://doaj.org/article/6beed1e1cb964f0284370588a6aaf233
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin, imparting to themselves the ability to respond to light in the absence of input from rod or cone photoreceptors. Since their discovery ipRGCs have been
Externí odkaz:
https://doaj.org/article/f63d11d7b6a94b9b963c157a03fe7526
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The preoptic area (POA) is critical for sleep regulation but its role in acute, non-circadian, light effects on sleep are unclear. The authors show that intrinsically photosensitive retinal ganglion cells provide substantial input into the POA and th
Externí odkaz:
https://doaj.org/article/c664d3c6338c42edb4b41a304a4d4995
Autor:
Aurelia A Mapps, Erica Boehm, Corinne Beier, William T Keenan, Jennifer Langel, Michael Liu, Michael B Thomsen, Samer Hattar, Haiqing Zhao, Emmanouil Tampakakis, Rejji Kuruvilla
Publikováno v:
eLife, Vol 11 (2022)
Satellite glia are the major glial cells in sympathetic ganglia, enveloping neuronal cell bodies. Despite this intimate association, the extent to which sympathetic functions are influenced by satellite glia in vivo remains unclear. Here, we show tha
Externí odkaz:
https://doaj.org/article/44dc22c124e54edda8a40b48710d2ced
Publikováno v:
iScience, Vol 6, Iss , Pp 299-305 (2018)
Summary: The master circadian pacemaker in mammals resides in the hypothalamic suprachiasmatic nuclei (SCN) and is synchronized to ambient light/dark cycles (i.e., photoentrainment). Melanopsin (Opn4) and classical rod-cone photoreceptors are believe
Externí odkaz:
https://doaj.org/article/1f5579236ef644c6b02294333532c6a1
Autor:
Adele R. Tufford, Jessica R. Onyak, Katelyn B. Sondereker, Jasmine A. Lucas, Aaron M. Earley, Pierre Mattar, Samer Hattar, Tiffany M. Schmidt, Jordan M. Renna, Michel Cayouette
Publikováno v:
Cell Reports, Vol 23, Iss 8, Pp 2416-2428 (2018)
Summary: Newborn neurons follow molecular cues to reach their final destination, but whether early life experience influences lamination remains largely unexplored. As light is among the first stimuli to reach the developing nervous system via intrin
Externí odkaz:
https://doaj.org/article/4f2dfa3ec4924e2ab2837074c56e88d8
Autor:
Adriano Dellapolla, Ian Kloehn, Harshida Pancholi, Ben Callif, David Wertz, Kayla E. Rohr, Matthew M. Hurley, Kimberly M. Baker, Samer Hattar, Marieke R. Gilmartin, Jennifer A. Evans
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Light improves cognitive function in humans; however, the neurobiological mechanisms underlying positive effects of light remain unclear. One obstacle is that most rodent models have employed lighting conditions that cause cognitive deficits
Externí odkaz:
https://doaj.org/article/933aa58583174768b0ff8c9ff02dcc4b