Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Sameh Obeid"'
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Akademický článek
Deciphering the mechanism of action of VP343, an antileishmanial drug candidate, in Leishmania infantum
Autor: Sameh Obeid, Eloisa Berbel-Manaia, Valérie Nicolas, Indira Dennemont, Julien Barbier, Jean-Christophe Cintrat, Daniel Gillet, Philippe M. Loiseau, Sébastien Pomel
Publikováno v: iScience, Vol 26, Iss 11, Pp 108144- (2023)
Summary: Antileishmanial chemotherapy is currently limited due to severe toxic side effects and drug resistance. Hence, new antileishmanial compounds based on alternative approaches, mainly to avoid the emergence of drug resistance, are needed. The p
Externí odkaz: https://doaj.org/article/dbcda9f2fa5048c280c47e5708a19e5b
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3
Atomic force microscopy of food assembly: Structural and mechanical insights at the nanoscale and potential opportunities from other fields
Autor: Sameh Obeid, Fanny Guyomarc'H
Publikováno v: Food Bioscience
Food Bioscience, Elsevier, 2020, 36, pp.100654. ⟨10.1016/j.fbio.2020.100654⟩
The atomic force microscope (AFM) has opened access to the nanoscale observation of molecular and colloidal structures in aqueous media, and of their dynamics upon environmental changes. As a miniature force scanner, it furthermore allows the correla
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5897beba54a673971590ac67273448
https://hal.inrae.fr/hal-02617534
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4
Development of a NanoBioAnalytical platform for 'on-chip' qualification and quantification of platelet-derived microparticles
Autor: Adam Ceroi, Guillaume Mourey, Philippe Saas, Wilfrid Boireau, Céline Elie-Caille, Sameh Obeid
Publikováno v: HAL
Biosensors and Bioelectronics
Biosensors and Bioelectronics, 2017
International audience; Blood microparticles (MPs) are small membrane vesicles (50-1000nm), derived from different cell types. They are known to play important roles in various biological processes and also recognized as potential biomarkers of vario
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b4740a83474ca06fa3649ac5ffdacb
https://doi.org/10.1016/j.bios.2016.08.100
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5
The adhesion of homogenized fat globules to proteins is increased by milk heat treatment and acidic pH: Quantitative insights provided by AFM force spectroscopy
Autor: Christelle Lopez, Anne Dolivet, Nadine Leconte, Gwénaël Jan, Arlette Leduc, Xiaoxi Wu, Sameh Obeid, Frédéric Gaucheron, Chantal Cauty, Florence Rousseau, Fanny Guyomarc'H, Gaëlle Tanguy
Publikováno v: Food Research International
Food Research International, Elsevier, 2019, ⟨10.1016/j.foodres.2019.108847⟩
Food Research International, Elsevier, 2020, 129, pp.108847. ⟨10.1016/j.foodres.2019.108847⟩
The rheological properties and microstructure of dairy gels involve the connectivity between milk fat globules (MFG) and casein micelles that is affected by technological processes such as milk homogenization and heat treatment. The underlying mechan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef9a277ca863a178ce0938b78df3103
https://hal.archives-ouvertes.fr/hal-02405809
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6
The surface properties of milk fat globules govern their interactions with the caseins: Role of homogenization and pH probed by AFM force spectroscopy
Autor: Xiaoxi Wu, Sameh Obeid, Hervé Guillemin, Christelle Lopez, Stéphane Pezennec, Fanny Guyomarc'H, Marie-Hélène Famelart, Grégory Francius, Frédéric Gaucheron, Chantal Cauty
Publikováno v: Colloids and Surfaces B: Biointerfaces
Colloids and Surfaces B: Biointerfaces, Elsevier, 2019, 182, pp.110363. ⟨10.1016/j.colsurfb.2019.110363⟩
The surface of milk fat globules consists of a biological membrane rich in polar lipids and glycoproteins. However, high shear stress applied upon homogenization disrupts the membrane and leads to the adsorption of casein micelles, as the major prote
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6075aca6b0365a729e266f03179ab3c7
https://hal.archives-ouvertes.fr/hal-02215870/file/1-s2.0-S0927776519304977-main.pdf
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7
The phase and charge of milk polar lipid membrane bilayers govern their selective interactions with proteins as demonstrated with casein micelles
Autor: Sameh Obeid, Alain Riaublanc, Fanny Guyomarc'H, Elisabeth David-Briand, Christelle Lopez, Frédéric Gaucheron
Publikováno v: Journal of Colloid and Interface Science
Journal of Colloid and Interface Science, Elsevier, 2019, 534, pp.279-290. ⟨10.1016/j.jcis.2018.09.033⟩
The biological membrane surrounding fat globules in milk (milk fat globule membrane; MFGM) is an interface involved in many biological functions and interactions with the surrounding proteins or lipolytic enzymes in the gastro-intestinal tract during
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861f12c152bde7c6e10ed8fac8c606fc
https://hal.archives-ouvertes.fr/hal-01887283
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8
NanoBioAnalytical characterization of extracellular vesicles in 75-nm nanofiltered human plasma for transfusion: a tool to improve transfusion safety
Autor: Thierry Burnouf, Benoit Le Roy, Ming Li Chou, Pei Shan Sung, Wilfrid Boireau, Sameh Obeid, Céline Elie-Caille, Shie Liang Hsieh
Publikováno v: Nanomedicine: Nanotechnology, Biology, and Medicine
Nanomedicine: Nanotechnology, Biology, and Medicine, 2019, 20, pp.101977
Nanomedicine: Nanotechnology, Biology and Medicine
Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2019, 20, pp.101977. ⟨10.1016/j.nano.2019.02.026⟩
ciencedirect.com/science/article/pii/S1549963419300619
International audience; Plasma transfusion induces some transfusion related acute lung injury (TRALI) mediated through neutrophil extracellular traps (NETs). We investigated whether extracellular vesicles (EVs) present in plasma or obtained from rest
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b79b2eef9b0e52715540a555822523
https://hal.archives-ouvertes.fr/hal-02371049
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9
On-chip detection, sizing and proteomics of extracellular vesicles
Autor: Sameh Obeid, Geraldine Lucchi, Thierry Burnouf, Wilfrid Boireau, Céline Caille
Publikováno v: International Society for Extracellular Vesicles
International Society for Extracellular Vesicles, May 2018, Barcelone, Spain
HAL
International audience; Microparticles are small extracellular vesicles (EVs) (from ~100 to 1000 nm) produced by different cell types, through the budding of the plasma membrane, while exosomes (from ~30 to 120 nm) originate from the endolysosomal pa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f2a99f0eae037344600681e8609ef4bb
https://hal.archives-ouvertes.fr/hal-02366559
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