Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sameh H. Abdelwahed"'
Autor:
Abdalrahman Khalifa, Manal M. Anwar, Walaa A. Alshareef, Eman A. El-Gebaly, Samia A. Elseginy, Sameh H. Abdelwahed
Publikováno v:
Molecules, Vol 29, Iss 19, p 4778 (2024)
Bacterial infection poses a serious threat to human life due to the rapidly growing resistance of bacteria to antibacterial drugs, which is a significant public health issue. This study was focused on the design and synthesis of a new series of 25 an
Externí odkaz:
https://doaj.org/article/c545b4349b1b4acab61d90e0a5525d37
Autor:
Heba T. Abdel-Mohsen, Manal M. Anwar, Nesreen S. Ahmed, Somaia S. Abd El-Karim, Sameh H. Abdelwahed
Publikováno v:
Molecules, Vol 29, Iss 4, p 875 (2024)
Cancer is a complicated, multifaceted disease that can impact any organ in the body. Various chemotherapeutic agents have a low selectivity and are very toxic when used alone or in combination with others. Resistance is one of the most important hurd
Externí odkaz:
https://doaj.org/article/75a0f2516ad84188bb2f621cfdf97360
Autor:
Rajendra Rathore, Sameh H. Abdelwahed
Publikováno v:
Molecules, Vol 28, Iss 9, p 3717 (2023)
A study of cofacially arrayed π-systems is of particular importance for the design of functional materials for efficient long-range intra-chain charge transfer through the bulk semiconducting materials in the layers of photovoltaic devices. The effe
Externí odkaz:
https://doaj.org/article/9fdbe59767dc4aad88d1b580f3a8394c
Publikováno v:
Molecules, Vol 27, Iss 18, p 5994 (2022)
We have designed and synthesized electron-rich calixarene derivatives, which undergo reversible electrochemical oxidation in a well-accessible potential range that allows the ready preparation and isolation of the corresponding cation radicals. Prepa
Externí odkaz:
https://doaj.org/article/796d842094ef48e487d567e2fb418560
Autor:
Yasmin M. Syam, Manal M. Anwar, Somaia S. Abd El-Karim, Khaled M. Elokely, Sameh H. Abdelwahed
Publikováno v:
Molecules, Vol 27, Iss 15, p 4924 (2022)
Herein, 2,3-dioxo-1,2,3,4-tetrahydroquinoxaline was used as a bio-isosteric scaffold to the phthalazinone motif of the standard drug Olaparib to design and synthesize new derivatives of potential PARP-1 inhibitory activity using the 6-sulfonohydrazid
Externí odkaz:
https://doaj.org/article/bb43890996e44af8bc37aa2d8e5e274d
Autor:
Sameh H. Abdelwahed, Lena V. Ivanova, Denan Wang, Sergey V. Lindeman, Rajendra Rathore, Scott A. Reid, Maxim V. Ivanov, Ainur Abzhanova, Tushar S. Navale
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 374:125-130
It is well known that upon electronic excitation various π-stacked dimers readily exhibit excimer formation, facilitated by a perfect sandwich-like arrangement between the chromophores. However, it is unclear whether such a dimer is also capable of
Publikováno v:
The Journal of Physical Chemistry C. 121:1552-1561
Among the π-conjugated poly-p-phenylene wires, fluorene-based poly-p-phenylene (FPPn) wires have been extensively explored for their potential as charge-transfer materials in functional photovoltaic devices. Herein, we undertake a systematic study o
Publikováno v:
The Journal of Organic Chemistry. 81:1627-1634
Multiple molecular wires braided together in a single assembly, termed as molecular cable, are promising next-generation materials for effective long-range charge transport. As an example of the platform for constructing molecular cables, 1,3,5-trifl
Autor:
R. David Britt, Tadhg P. Begley, Derek M. Gagnon, Angad P. Mehta, Sameh H. Abdelwahed, Troy A. Stich
Publikováno v:
Journal of the American Chemical Society, vol 140, iss 40
Organisms that perform the de novo biosynthesis of cobalamin (vitamin B12) do so via unique pathways depending on the presence of oxygen in the environment. The anaerobic biosynthesis pathway of 5,6-dimethylbenzimidazole, the so-called “lower ligan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ea64c28b6b067a78ec7998296f33c4
https://europepmc.org/articles/PMC6435355/
https://europepmc.org/articles/PMC6435355/
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1854:1073-1077
The first step in the biosynthesis of the molybdopterin cofactor involves an unprecedented insertion of the purine C8 carbon between the C2' and C3' carbons of the ribose moiety of GTP. Here we review mechanistic studies on this remarkable transforma