Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sameh Geha"'
Autor:
Camille Plante, Teddy Mohamad, Dhanushka Hewa Bostanthirige, Michel Renaud, Harsimran Sidhu, Michel ElChoueiry, Jean-Paul Sabo Vatasescu, Mikael Poirier, Sameh Geha, Jean-Philippe Brosseau
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0301040 (2024)
Neurofibromatosis Type I (NF1) is a rare genetic disorder. NF1 patients frequently develop a benign tumor in peripheral nerve plexuses called plexiform neurofibroma. In the past two decades, tissue-specific Nf1 knockout mouse models were developed us
Externí odkaz:
https://doaj.org/article/e9f3060cd642481ebd6586c66c39041d
Autor:
Marie-Christine Milot, Ophélie Bélissant-Benesty, Véronique Dumulon-Perreault, Samia Ait-Mohand, Sameh Geha, Patrick O. Richard, Étienne Rousseau, Brigitte Guérin
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionWe have previously shown that copper-64 (64Cu)-DOTHA2-PSMA can be used for positron emission tomography (PET) imaging of prostate cancer. Owing to the long-lasting, high tumoral uptake of 64Cu-DOTHA2-PSMA, the objective of the current stu
Externí odkaz:
https://doaj.org/article/f832897046684f62a147ccc61a2f10bc
Autor:
Anaïs Chauvin, Chang-Shu Wang, Sameh Geha, Perrine Garde-Granger, Alex-Ane Mathieu, Vincent Lacasse, François-Michel Boisvert
Publikováno v:
Clinical Proteomics, Vol 15, Iss 1, Pp 1-16 (2018)
Abstract Background Colorectal cancer is the third most common and the fourth most lethal cancer in the world. In the majority of cases, patients are diagnosed at an advanced stage or even metastatic, thus explaining the high mortality. The standard
Externí odkaz:
https://doaj.org/article/aad51dac41954c5fb3e531e2d25087ff
Autor:
Jean-Philippe Brosseau, Lu Q. Le, Sameh Geha, Maude Lévesque, Dhanushka Hewa Bostanthirige, Camille Plante, Yong Wang, Zhiguo Chen, Krystina Rhéaume
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::907321f734ce65d1f97bfb9ab7dcacb7
https://doi.org/10.3791/64974
https://doi.org/10.3791/64974
Publikováno v:
The FEBS Journal. 288:5459-5473
In the intestine, mucins are expressed and secreted by goblet cells and enterocytes in a constitutive manner and in response to secretagogues to form a protective mucus layer. This protective barrier is often lost in inflammatory bowel disease (IBD).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c362676025875ca17d69609ff5028863
https://doi.org/10.1111/febs.15819
https://doi.org/10.1111/febs.15819
Autor:
Wan Lu Jia, Audrey Michaud, Sameh Geha, Jean-Paul Praud, Charlène Nadeau, Djamal Djeddi, Nathalie Samson
Publikováno v:
Pediatric Research. 89:496-501
BACKGROUND Although it is commonly accepted that upper airway obstruction (UAO) increases gastroesophageal reflux (GER), the link is poorly understood and insufficiently documented. In addition, while hypoxia is often encountered in infants with UAO,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::738a4701abbabe42f38a7e9ef1bb4585
https://doi.org/10.1038/s41390-020-0920-8
https://doi.org/10.1038/s41390-020-0920-8
Publikováno v:
The FEBS journalReferences. 288(18)
In the intestine, mucins are expressed and secreted by goblet cells and enterocytes in a constitutive manner and in response to secretagogues to form a protective mucus layer. This protective barrier is often lost in inflammatory bowel disease (IBD).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7bbd30808a3996522f38778d26b65790
https://pubmed.ncbi.nlm.nih.gov/33713543
https://pubmed.ncbi.nlm.nih.gov/33713543
Autor:
Sameh Geha, Martin Savard, Veronica Bovenzi, Jérôme Côté, Sylvain Chemtob, Fernand Gobeil, Andrée Lessard, Witold Neugebauer, Céléna Dubuc
Publikováno v:
Journal of Cellular Physiology. 234:2851-2865
High nuclear expression of G protein-coupled receptors, including kinin B1 receptors (B1R), has been observed in several human cancers, but the clinical significance of this is unknown. We put forward the hypothesis that these "nuclearized" kinin B1R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aaccfe4eac0e9dc164861b91500e872
https://doi.org/10.1002/jcp.27103
https://doi.org/10.1002/jcp.27103
The G protein-coupled P2Y6 receptor promotes colorectal cancer tumorigenesis by inhibiting apoptosis
Autor:
Fernand-Pierre Gendron, Morgane Placet, Guillaume Arguin, Christine Jones, Sameh Geha, Bernand Robaye, Caroline M. Molle, Julie Carrier, Jean-Philippe Babeu, François Boudreau
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:1539-1551
Colorectal tumors are immersed in an array of tumor-promoting factors including extracellular nucleotides such as uridine 5'‑diphosphate (UDP). UDP is the endogenous agonist of the G protein-coupled P2Y6 receptor (P2Y6R), which may contribute to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4113a2a4722e290ee75243b98b1da398
https://doi.org/10.1016/j.bbadis.2018.02.008
https://doi.org/10.1016/j.bbadis.2018.02.008
Autor:
Kevin Whittingstall, Sameh Geha, Réjean Lebel, Benoit Paquette, Martin Lepage, Luc Tremblay, Philippe Sarret, Maxime Descoteaux, Julie Constanzo, Matthieu Dumont, Laurence Masson-Côté
Publikováno v:
Magnetic Resonance in Medicine. 80:1614-1625
Purpose The analysis of biological and mesoscopic structures properties by diffusion MRI (dMRI) in brain after radiation therapy remains challenging. In our study, we described the consequences associated with an unwanted dose to healthy tissue, asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108d57c652fffa405b3636e9f9d2b99c
https://doi.org/10.1002/mrm.27112
https://doi.org/10.1002/mrm.27112