Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Sameer S Kulkarni"'
Autor:
Luke J. Dowman, Sameer S. Kulkarni, Juan V. Alegre-Requena, Andrew M. Giltrap, Alexander R. Norman, Ashish Sharma, Liliana C. Gallegos, Angus S. Mackay, Adarshi P. Welegedara, Emma E. Watson, Damian van Raad, Gerhard Niederacher, Susanne Huhmann, Nicholas Proschogo, Karishma Patel, Mark Larance, Christian F. W. Becker, Joel P. Mackay, Girish Lakhwani, Thomas Huber, Robert S. Paton, Richard J. Payne
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The modification of peptides and proteins for application in drug discovery and chemical biology is currently a rapidly growing field of research. Here, the authors report a photocatalytic diselenide contraction method for the dimerization and site-s
Externí odkaz:
https://doaj.org/article/ada06c11e046408eba2e63c6b196deda
Autor:
Samuel D. Robinson, Lucas Kambanis, Daniel Clayton, Hannes Hinneburg, Leo Corcilius, Alexander Mueller, Andrew A. Walker, Angelo Keramidas, Sameer S. Kulkarni, Alun Jones, Irina Vetter, Morten Thaysen-Andersen, Richard J. Payne, Glenn F. King, Eivind A.B. Undheim
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103175- (2021)
Summary: Ants (Hymenoptera: Formicidae) are familiar inhabitants of most terrestrial environments. Although we are aware of the ability of many species to sting, knowledge of ant venom chemistry remains limited. Herein, we describe the discovery and
Externí odkaz:
https://doaj.org/article/78baef6776294d269907493bbcce2af2
Autor:
Audrey Sambeat, Joanna Ratajczak, Magali Joffraud, José L. Sanchez-Garcia, Maria P. Giner, Armand Valsesia, Judith Giroud-Gerbetant, Miriam Valera-Alberni, Angelique Cercillieux, Marie Boutant, Sameer S. Kulkarni, Sofia Moco, Carles Canto
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nicotinamide adenine dinucleotide (NAD+) sustains cellular energy metabolism, functions as a substrate of Sirt and PARP enzymes, and its supplementation is explored therapeutically in aging and other contexts. Here the authors provide insight into th
Externí odkaz:
https://doaj.org/article/d868646ab078447ea44fb258c12312d5
Autor:
Katya Nacheva, Sameer S. Kulkarni, Mintesinot Kassu, David Flanigan, Andrii Monastyrskyi, Iredia D. Iyamu, Kenichiro Doi, Megan Barber, Niranjan Namelikonda, Jeremiah D. Tipton, Prakash Parvatkar, Hong-Gang Wang, Roman Manetsch
Publikováno v:
Journal of Medicinal Chemistry. 66:5196-5207
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75b0fd02e8e18ee0236e3fbf5b0e0503
https://doi.org/10.1021/acs.jmedchem.3c00108
https://doi.org/10.1021/acs.jmedchem.3c00108
Publikováno v:
Welding International. 36:387-393
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d32fa42113d32dbb8e6c82a522cff6d
https://doi.org/10.1080/09507116.2022.2087569
https://doi.org/10.1080/09507116.2022.2087569
Autor:
Joanna Ratajczak, Magali Joffraud, Samuel A. J. Trammell, Rosa Ras, Núria Canela, Marie Boutant, Sameer S. Kulkarni, Marcelo Rodrigues, Philip Redpath, Marie E. Migaud, Johan Auwerx, Oscar Yanes, Charles Brenner, Carles Cantó
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Raising cellular levels of the metabolic cofactor NAD+ reverses key indicators of aging. Here, Ratajczak et al. show that cellular levels of NAD+ depend on the extracellular catalytic activity of NRK1, which processes two NAD+precursors, nicotinamide
Externí odkaz:
https://doaj.org/article/bed4a8bce0a947e6b296d8080b0074aa
Autor:
Marie Boutant, Sameer S. Kulkarni, Magali Joffraud, Frédéric Raymond, Sylviane Métairon, Patrick Descombes, Carles Cantó
Publikováno v:
Cell Reports, Vol 14, Iss 9, Pp 2068-2075 (2016)
Caloric restriction (CR) has been shown to prevent the onset of insulin resistance and to delay age-related physiological decline in mammalian organisms. SIRT1, a NAD+-dependent deacetylase enzyme, has been suggested to mediate the adaptive responses
Externí odkaz:
https://doaj.org/article/646dca569ff44c9b95ebcbfa75c3fae7
Publikováno v:
Chemical Science
The development of an iterative one-pot peptide ligation strategy is described that capitalises on the rapid and efficient nature of the diselenide–selenoester ligation reaction, together with photodeselenisation chemistry. This ligation strategy h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9199ca030619c70991067f05b7120f91
http://europepmc.org/articles/PMC8317654
http://europepmc.org/articles/PMC8317654
Publikováno v:
International Journal of Engineering and Advanced Technology. 10:21-24
Metal matrix composite (MMC’s) are very much familiar in the field like automobile and aerospace industries owing to their excellent wear and mechanical properties . The fundamental aim of this paper is to augment cognizance amongst the researchers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e70c144076940eef2fe884dbb4cffbb7
https://doi.org/10.35940/ijeat.c1006.02103s21
https://doi.org/10.35940/ijeat.c1006.02103s21
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2530
Peptides bearing C-terminal thioester and selenoester functionalities are essential precursors for the chemical synthesis of larger proteins using ligation chemistry, including native chemical ligation (NCL) and diselenide-selenoester ligation (DSL).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0a4bf909e9b7411abe009a71388992e
https://pubmed.ncbi.nlm.nih.gov/35761046
https://pubmed.ncbi.nlm.nih.gov/35761046