Výsledky vyhledávání - "Sameer A. Khan"

Akademický článek

Unveiling the mechanisms and challenges of cancer drug resistance

Autor: Sameer Ullah Khan, Kaneez Fatima, Shariqa Aisha, Fayaz Malik

Publikováno v: Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-26 (2024)

Abstract Cancer treatment faces many hurdles and resistance is one among them. Anti-cancer treatment strategies are evolving due to innate and acquired resistance capacity, governed by genetic, epigenetic, proteomic, metabolic, or microenvironmental

Externí odkaz: https://doaj.org/article/9d7fbf06779c4a2da350eb7763adea4c

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Akademický článek

Reoperation and revision rates at ten years after 1,312 cemented Thompson’s hemiarthroplasties any need to change to a different implant?

Autor: Sameer K. Khan, Ben Tyas, Amy Shenfine, Simon S. Jameson, Dominic S. Inman, Scott D. Muller, Mike R. Reed

Publikováno v: Bone & Joint Open, Vol 3, Iss 9, Pp 710-715 (2022)

AimsDespite multiple trials and case series on hip hemiarthroplasty designs, guidance is still lacking on which implant to use. One particularly deficient area is long-term outcomes. We present over 1,000 consecutive cemented Thompson’s hemiarthrop

Externí odkaz: https://doaj.org/article/137db65744dd4f749daf389385228730

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Akademický článek

Activation of lysosomal mediated cell death in the course of autophagy by mTORC1 inhibitor

Autor: Sameer Ullah Khan, Anup Singh Pathania, Abubakar Wani, Kaneez Fatima, Mubashir Javed Mintoo, Baseerat Hamza, Masroor Ahmad Paddar, Wadhwa Bhumika, Loveleena Kour Anand, Mir Shahid Maqbool, Sameer Ahmad Mir, Jaspreet Kour, Vunnam Venkateswarlu, Dilip Manikrao Mondhe, Sanghapal D. Sawant, Fayaz Malik

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Abstract Lysosomal biogenesis plays a vital role in cell fate. Under certain conditions, excessive lysosomal biogenesis leads to susceptibility for lysosomal membrane permeabilization resulting in various pathological conditions including cell death.

Externí odkaz: https://doaj.org/article/4068e835a7fa4caf83866b11c58f2661

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Akademický článek

Prenatal treprostinil reduces the pulmonary hypertension phenotype in the rat model of congenital diaphragmatic hernia

Autor: Felix Rafael De Bie, Christopher Gates Halline, Travis Kotzur, Kevin Hayes, Christopher Copeland Rouse, Jonathan Chang, Abby Christine Larson, Sameer Ahmad Khan, Ashley Spina, Samantha Tilden, Francesca Maria Russo, Holly Lee Hedrick, Jan Deprest, Emily Anne Partridge

Publikováno v: EBioMedicine, Vol 81, Iss , Pp 104106- (2022)

Summary: Background: Persistent pulmonary hypertension (PH) causes significant mortality and morbidity in infants with congenital diaphragmatic hernia (CDH). Since pulmonary vascular abnormalities in CDH develop early during foetal development, we hy

Externí odkaz: https://doaj.org/article/072be8d55c5843a19714b3965da95bfe

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Akademický článek

Fracture resistance of endodontically treated teeth after instrumentation with different nickel titanium systems

Autor: Sameer Ahmed Khan, Rajni Nagpal, Udai Pratap Singh, Nida Mehmood, Meenal Agarwal, Zaid Nabi Khan

Publikováno v: Endodontology, Vol 32, Iss 3, Pp 118-123 (2020)

Aim: To compare the vertical root fractures (VRFs) resistance of teeth instrumented with ProTaper Universal, ProTaper Next, HyFlex CM and HERO Shaper nickel titanium (NiTi) rotary systems and obturated with compatible gutta-percha cones using the sin

Externí odkaz: https://doaj.org/article/e6735395032645058666fcae7122a3f5

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