Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Samarth D. Thakore"'
Autor:
Satyajit R. Datir, Dinesh Kumar, Pradeep Kumar, Sanyog Jain, Arvind Kumar Bansal, Bhargavi Nallamothu, Samarth D. Thakore, Mrudula H. Bele
Publikováno v:
Applied Sciences, Vol 11, Iss 12, p 5604 (2021)
In the present study, aprepitant (APT) was selected to find its suitable crystal habit, which can improve its existing poor dissolution and manufacturing processability. Solvents were screened out for solubility analysis of APT and further crystal ha
Externí odkaz:
https://doaj.org/article/23197108c23046988fa7e2189b842cd2
Autor:
Samarth D. Thakore, Katangur Vishruth Reddy, Ajay K. Dantuluri, Deepika Patel, Akshant Kumawat, Vaibhav Sihorkar, Chinmay Ghoroi, Arvind K. Bansal
Publikováno v:
Pharmaceutical research. 39(12)
Pharmaceutical tablet manufacturing has seen a paradigm shift toward continuous manufacturing and twin-screw granulation-based technologies have catalyzed this shift. Twin-screw granulator can simultaneously perform unit operations like mixing, granu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc9ea5e768cf4d0e5e6726fdb01a637
https://pubmed.ncbi.nlm.nih.gov/36002616
https://pubmed.ncbi.nlm.nih.gov/36002616
Publikováno v:
Drug Development Research. 81:3-22
Crystallization is an important and difficult to control unit operation in the pharmaceutical industry. Crystallization can control molecular (i.e., polymorphism) and particulate (i.e., particle size and crystal habit) properties of active pharmaceut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45baf2e1f0b8396a3e20f9705f975f8f
https://doi.org/10.1002/ddr.21622
https://doi.org/10.1002/ddr.21622
Publikováno v:
Molecular pharmaceutics. 18(8)
In the pharmaceutical industry, poorly water-soluble drugs require enabling technologies to increase apparent solubility in the biological environment. Amorphous solid dispersion (ASD) has emerged as an attractive strategy that has been used to marke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea718b06b146828cce1c5ced2b9e9d15
https://pubmed.ncbi.nlm.nih.gov/34041914
https://pubmed.ncbi.nlm.nih.gov/34041914
Autor:
Ridhima Singh, Arijita Manna, Arvind Sirvi, Abhay T. Sangamwar, Samarth D. Thakore, Arvind K. Bansal, Sanjali S Panigrahi, Vikram C Joshi
Publikováno v:
International journal of pharmaceutics. 607
Supersaturating drug delivery systems (SDDS) enhance the oral absorption of poorly water-soluble drugs by achieving a supersaturated state in the gastrointestinal tract. The maintenance of a supersaturated state is decided by the complex interplay am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12457625c33fee3bb2d8cf451c1a0deb
https://pubmed.ncbi.nlm.nih.gov/34332060
https://pubmed.ncbi.nlm.nih.gov/34332060
Publikováno v:
International journal of pharmaceutics. 585
Spray drying is an industrially viable technique that can be used for modulation of the physical form of Active Pharmaceutical Ingredients (API), which is governed by inherent crystallization tendency and processing parameters during spray drying. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b67c559804dac9b2c151bb206bf3954
https://pubmed.ncbi.nlm.nih.gov/32522504
https://pubmed.ncbi.nlm.nih.gov/32522504
Autor:
Arvind K. Bansal, Bhargavi Nallamothu, Sanyog Jain, Pradeep Kumar, Mrudula H. Bele, Dinesh Kumar, Satyajit R. Datir, Samarth D. Thakore
Publikováno v:
Applied Sciences
Volume 11
Issue 12
Applied Sciences, Vol 11, Iss 5604, p 5604 (2021)
Volume 11
Issue 12
Applied Sciences, Vol 11, Iss 5604, p 5604 (2021)
In the present study, aprepitant (APT) was selected to find its suitable crystal habit, which can improve its existing poor dissolution and manufacturing processability. Solvents were screened out for solubility analysis of APT and further crystal ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2f80322f85993ad36fef9be0fd3fbd
https://doi.org/10.3390/app11125604
https://doi.org/10.3390/app11125604
Publikováno v:
Journal of pharmaceutical sciences. 109(2)
NanoCrySP™ is a novel spray-drying-based technology for the generation of nanocrystalline solid dispersions of active pharmaceutical ingredients embedded in the matrix of small molecule excipients. Active pharmaceutical ingredient first appears as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfefab686ea77a1486363260b2b7ae6d
https://pubmed.ncbi.nlm.nih.gov/31705872
https://pubmed.ncbi.nlm.nih.gov/31705872
The present work investigated effect of process parameters on phase behavior of aspirin (ASP) solution and ASP particle size during freeze concentration. ASP solution (3% w/w in 40% w/w TBA in water) was studied using differential scanning calorimetr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df54120827ba40e91c85d3c0924242ae
Autor:
Ganesh Shete, Rahul P. Gangwal, Abhay T. Sangamwar, Ajit S. Narang, Samarth D. Thakore, Poonam Singh Thakur, Arvind K. Bansal
Publikováno v:
AAPS PharmSciTech. 20(5)
There is an overgrowing emphasis on supersaturating drug delivery systems (SDDS) with increase in number of poorly water-soluble compounds. However, biopharmaceutical performance from these formulations is limited by phase transformation to stable cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410951f6c8302ff07c17a247e6129e4a
https://pubmed.ncbi.nlm.nih.gov/31041552
https://pubmed.ncbi.nlm.nih.gov/31041552