Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Samarjit Jana"'
Autor:
Samarjit Jana, Mainak Mondal, Sagar Mahale, Bhavana Gupta, Kaval Reddy Prasasvi, Lekha Kandasami, Neha Jha, Abhishek Chowdhury, Vani Santosh, Chandrasekhar Kanduri, Kumaravel Somasundaram
Publikováno v:
eLife, Vol 12 (2024)
In tumors with WT p53, alternate mechanisms of p53 inactivation are reported. Here, we have identified a long noncoding RNA, PITAR (p53 Inactivating TRIM28 Associated RNA), as an inhibitor of p53. PITAR is an oncogenic Cancer/testis lncRNA and is hig
Externí odkaz:
https://doaj.org/article/0470f038a6d0472a8503c0cc6ba390ec
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Most of the human genome, except for a small region that transcribes protein-coding RNAs, was considered junk. With the advent of RNA sequencing technology, we know that much of the genome codes for RNAs with no protein-coding potential. Long non-cod
Externí odkaz:
https://doaj.org/article/09411b4a56024e97b9b066f52bca1748
Autor:
Samarjit Jana, Mainak Mondal, Sagar Mahale, Bhavana Gupta, Kaval Reddy Prasasvi, Lekha Kandasami, Neha Jha, Abhishek Chowdhury, Vani Santosh, Chandrasekhar Kanduri, Kumaravel Somasundaram
In tumors with WT p53, alternate mechanisms of p53 inactivation are reported. Here we have identified a long noncoding RNA, PITAR (p53InactivatingTRIM28associatedRNA), as an inhibitor of p53. PITAR is highly expressed in glioblastoma (GBM) and glioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68e0f1ce60e446abae415ad304521070
https://doi.org/10.1101/2023.04.11.536370
https://doi.org/10.1101/2023.04.11.536370
Publikováno v:
Molecular and cellular biochemistry. 477(4)
Cytotoxic chemotherapy dominates the field of cancer treatment. Consequently, anticancer phytochemicals are largely screened on the basis of their cytotoxicity towards cancer cells which are achieved at higher doses, leading to various toxic side eff
Publikováno v:
BioFactors. 45:401-415
Tumor hypoxia is positively correlated with tumor aggressiveness and hence is a negative prognostic factor in cancer. As normal cells usually do not experience such low oxygen levels, hypoxic cell signaling has attracted significant attention for the
Publikováno v:
Chemico-Biological Interactions. 285:59-68
Cancer cells possess elevated ROS coupled with increased levels of antioxidant enzymes which render them resistant against cytotoxic chemotherapies. Therefore, an understanding of the interaction between key molecules involved in stress adaptive mech
Autor:
Subhrangsu Chatterjee, Meghomukta Mukherjee, Abhay T. Sangamwar, Jyotsna Bhat, Gopeswar Mukherjee, Samarjit Jana, Kartick Patra, Pallabi Sengupta, Rahul P. Gangwal, Satya Prakash Tripathi, Arnab Sarkar, Deba Prasad Mandal, Jagannath Jana, Shamee Bhattacharjee, Joyita Hazra, Soma Mondal, Anindya Biswas
Publikováno v:
Oncotarget
Discovery of anti-metastatic drugs is of immense clinical significance as metastasis is responsible for 90% of all cancer deaths. Here we report the inhibitory effect of a bis schiff base (M2) on cancer cell migration and invasion in vitro and in viv
Publikováno v:
BioFactors (Oxford, England). 45(3)
Tumor hypoxia is positively correlated with tumor aggressiveness and hence is a negative prognostic factor in cancer. As normal cells usually do not experience such low oxygen levels, hypoxic cell signaling has attracted significant attention for the
Autor:
Ikbal Azahar, Abhishek Kundu, Zahed Hossain, Samarjit Jana, Sankhajit Roy, Sinchan Adhikari, Arun K. Shaw, Supriya Ghosh, Ang Rinzing Sherpa
Publikováno v:
Environmental and Experimental Botany. 130:53-67
The present study assesses the impact of arsenate (AsV) stress on maize ( Zea mays L.) seedlings. Three different levels of AsV stress (25, 50 and 100 μM Na 2 HAsO 4 ·7H 2 O) were imposed and seedling growth performances were studied at 2d and 4d o
Publikováno v:
RSC Advances. 5:56549-56559
The clinical outcome of chemotherapy in cancer treatment is limited due to severe side effects. There has been a mixed response in experimenting with combinations of conventional chemotherapy with dietary agents to improve the therapeutic outcome. Th