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pro vyhledávání: '"Samara E Hanna"'
Publikováno v:
ACS Omega, Vol 3, Iss 11, Pp 16281-16291 (2018)
Externí odkaz:
https://doaj.org/article/dec7ec7f4ad34a0eb47284eeab8bbaad
Cyclic Peptides as Protein Kinase Inhibitors: Structure-Activity Relationship and Molecular Modeling
Autor:
Saghar Mozaffari, Samara E Hanna, Rakesh Tiwari, Michel F. Sanner, Simin Rahighi, Keykavous Parang, Khalid Zoghebi
Publikováno v:
J Chem Inf Model
Under-expression or over-expression of protein kinases has been shown to be associated with unregulated cell signal transduction in cancer cells. Therefore, there is a major interest in designing protein kinase inhibitors as anticancer agents. We hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b58f25fcf8a58f8baf732453e55f572
https://europepmc.org/articles/PMC8238896/
https://europepmc.org/articles/PMC8238896/
Publikováno v:
ACS Omega, Vol 3, Iss 11, Pp 16281-16291 (2018)
ACS Omega
ACS Omega
Cyclic peptides containing tryptophan (W) and arginine (R) residues, [WR]5, [WR]6, [WR]7, [WR]8, and [WR]9, were synthesized through Fmoc solid-phase chemistry to compare their molecular transporter efficiency. The in vitro cytotoxicity of the peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b86bb678eb505667284c9864f87888b
https://doaj.org/article/dec7ec7f4ad34a0eb47284eeab8bbaad
https://doaj.org/article/dec7ec7f4ad34a0eb47284eeab8bbaad