Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Samara Braga do Nascimento"'
Autor:
Guilherme Curty Lechuga, Júlio Cesar Borges, Claudia Magalhães Calvet, Humberto Pinheiro de Araújo, Aline Araujo Zuma, Samara Braga do Nascimento, Maria Cristina Machado Motta, Alice Maria Rolim Bernardino, Mirian Claudia de Souza Pereira, Saulo Cabral Bourguignon
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 6, Iss 3, Pp 154-164 (2016)
Chagas disease is a neglected tropical disease caused by the flagellated protozoan Trypanosoma cruzi. The current drugs used to treat this disease have limited efficacy and produce severe side effects. Quinolines, nitrogen heterocycle compounds that
Externí odkaz:
https://doaj.org/article/4a2648c0a17b48edabc8f84da8374811
Autor:
Maria Cristina M. Motta, Alice M. R. Bernardino, Julio C. Borges, Samara Braga do Nascimento, Humberto Pinheiro de Araújo, Aline Araujo Zuma, Guilherme C. Lechuga, Claudia M. Calvet, Mirian Claudia de Souza Pereira, Saulo Cabral Bourguignon
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance, Vol 6, Iss 3, Pp 154-164 (2016)
International Journal for Parasitology: Drugs and Drug Resistance, Vol 6, Iss 3, Pp 154-164 (2016)
Chagas disease is a neglected tropical disease caused by the flagellated protozoan Trypanosoma cruzi. The current drugs used to treat this disease have limited efficacy and produce severe side effects. Quinolines, nitrogen heterocycle compounds that
Autor:
Samara Braga do Nascimento, Rodrigo Tonioni Vieira, Carlos E. R. Coutinho, Suzana Corte-Real, Saulo Cabral Bourguignon, Carlos Rangel Rodrigues, Carolina C. G. Bottino, R.T. Pinho, Helena Carla Castro, Maria de Fátima Madeira, Alice M. R. Bernardino, Dilvani Oliveira Santos
Publikováno v:
Parasitology Research. 103:1-10
Leishmaniasis is a disease caused by flagellate protozoan Leishmania spp. and represents an emergent illness with high morbidity and mortality in the tropics and subtropics. Since the discovery of the first drugs for Leishmaniasis treatment (i.e., pe
Autor:
Franklin Souza-Silva, R.T. Pinho, Samara Braga do Nascimento, Carlos Roberto Alves, Wellington Seguis da Silva, Paula F. Carneiro, Bernardo Acácio Santini Pereira, Saulo Cabral Bourguignon
Publikováno v:
Experimental parasitology. 147
In this work, we analyze the leishmanicidal effects of epoxy-α-lapachone on Leishmania (Viannia) braziliensis and Leishmania (Leishmania) amazonensis. Promasigotes and amastigotes (inhabiting human macrophages) from both species were assayed to veri
Autor:
Paula F. Carneiro, Alice S.B. Rocha, Samara Braga do Nascimento, Saulo Cabral Bourguignon, Maria do Carmo F. R. Pinto, Guilherme C. Lechuga, Vitor F. Ferreira
Publikováno v:
Proceedings of the 15th Brazilian Meeting on Organic Synthesis Proceedings.
Chagas disease is an endemic disease caused by T. cruzi. Approximately 16 to 18 million people are infected and 50000 individuals die every year from this disease. Only two drugs have been used since the 70s: nifurtimox and benznidazole. Several synt
Autor:
Paula F. Carneiro, Dilvani Oliveira Santos, Vitor F. Ferreira, Jackson A. L. C. Resende, Guilherme C. Lechuga, Samara Braga do Nascimento, Saulo Cabral Bourguignon, Maria do Carmo F. R. Pinto, Antonio V. Pinto, Helvécio M. dos Santos Júnior
Publikováno v:
Bioorganicmedicinal chemistry. 20(16)
New oxirane derivatives were synthesized using six naphthoquinones as the starting materials. Our biological results showed that these oxiranes acted as trypanocidal agents against Trypanosoma cruzi with minimal cytotoxicity in the VERO cell line com