Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Samar Sadeghi"'
Autor:
Andreas Kerstan, Kathrin Dieter, Elke Niebergall-Roth, Sabrina Klingele, Michael Jünger, Christoph Hasslacher, Georg Daeschlein, Lutz Stemler, Ulrich Meyer-Pannwitt, Kristin Schubert, Gerhard Klausmann, Titus Raab, Matthias Goebeler, Korinna Kraft, Jasmina Esterlechner, Hannes M. Schröder, Samar Sadeghi, Seda Ballikaya, Martin Gasser, Ana M. Waaga-Gasser, George F. Murphy, Dennis P. Orgill, Natasha Y. Frank, Christoph Ganss, Karin Scharffetter-Kochanek, Markus H. Frank, Mark A. Kluth
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-25 (2022)
Abstract Background While rapid healing of diabetic foot ulcers (DFUs) is highly desirable to avoid infections, amputations and life-threatening complications, DFUs often respond poorly to standard treatment. GMP-manufactured skin-derived ABCB5+ mese
Externí odkaz:
https://doaj.org/article/4819e8d8b5ba4b6b811f719469da6383
Autor:
Alexandra Norrick, Jasmina Esterlechner, Elke Niebergall-Roth, Ulf Dehio, Samar Sadeghi, Hannes M. Schröder, Seda Ballikaya, Nicole Stemler, Christoph Ganss, Kathrin Dieter, Ann-Kathrin Dachtler, Patrick Merz, Saadettin Sel, James Chodosh, Claus Cursiefen, Natasha Y. Frank, Gerd U. Auffarth, Bruce Ksander, Markus H. Frank, Mark A. Kluth
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-21 (2021)
Abstract Background While therapeutic success of the limbal tissue or cell transplantation to treat severe cases of limbal stem cell (LSC) deficiency (LSCD) strongly depends on the percentage of LSCs within the transplanted cells, prospective LSC enr
Externí odkaz:
https://doaj.org/article/05442d04f1184b4784987718c697fe9b
Autor:
Seda Ballikaya, Samar Sadeghi, Elke Niebergall-Roth, Laura Nimtz, Jens Frindert, Alexandra Norrick, Nicole Stemler, Nicole Bauer, Yvonne Rosche, Vanessa Kratzenberg, Julia Pieper, Tina Ficek, Markus H. Frank, Christoph Ganss, Jasmina Esterlechner, Mark A. Kluth
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Background Human dermal mesenchymal stromal cells (MSCs) expressing the ATP-binding cassette (ABC) efflux transporter ABCB5 represent an easily accessible MSC population that, based on preclinical and first-in-human data, holds significant p
Externí odkaz:
https://doaj.org/article/0ff6375b1ba34bbea869d8126b38c98d
Autor:
Andreas Kerstan, Kathrin Dieter, Elke Niebergall-Roth, Ann-Kathrin Dachtler, Korinna Kraft, Markus Stücker, Georg Daeschlein, Michael Jünger, Tobias Görge, Ulrich Meyer-Pannwitt, Cornelia Erfurt-Berge, Charlotte von Engelhardt, Andreas Klare, Christiane Pfeiffer, Jasmina Esterlechner, Hannes M. Schröder, Martin Gasser, Ana M. Waaga-Gasser, Matthias Goebeler, Seda Ballikaya, Samar Sadeghi, George F. Murphy, Dennis P. Orgill, Natasha Y. Frank, Christoph Ganss, Karin Scharffetter-Kochanek, Markus H. Frank, Mark A. Kluth
Publikováno v:
JID Innovations, Vol 2, Iss 1, Pp 100067- (2022)
A significant number of chronic venous ulcers (CVUs) fail to heal despite guideline-conform standards of care. Skin-derived ABCB5+ mesenchymal stem cells can dampen the sustained IL-1β‒driven inflammation present in chronic wounds. On the basis of
Externí odkaz:
https://doaj.org/article/30269062a0c04e579251c083a6768869
Autor:
Dimitra Kiritsi, Kathrin Dieter, Elke Niebergall-Roth, Silvia Fluhr, Cristina Daniele, Jasmina Esterlechner, Samar Sadeghi, Seda Ballikaya, Leoni Erdinger, Franziska Schauer, Stella Gewert, Martin Laimer, Johann W. Bauer, Alain Hovnanian, Giovanna Zambruno, May El Hachem, Emmanuelle Bourrat, Maria Papanikolaou, Gabriela Petrof, Sophie Kitzmüller, Christen L. Ebens, Markus H. Frank, Natasha Y. Frank, Christoph Ganss, Anna E. Martinez, John A. McGrath, Jakub Tolar, Mark A. Kluth
Publikováno v:
JCI Insight, Vol 6, Iss 22 (2021)
BACKGROUND Recessive dystrophic epidermolysis bullosa (RDEB) is a rare, devastating, and life-threatening inherited skin fragility disorder that comes about due to a lack of functional type VII collagen, for which no effective therapy exists. ABCB5+
Externí odkaz:
https://doaj.org/article/b73355f8e6714783859f9acfbd51109d
Autor:
Daniela Nardozi, Stefania Palumbo, Arif ul Maula Khan, Carsten Sticht, Karen Bieback, Samar Sadeghi, Mark Andreas Kluth, Michael Keese, Norbert Gretz
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 9, p 2601 (2022)
Cystic kidney disease (CKD) is a heterogeneous group of genetic disorders and one of the most common causes of end-stage renal disease. Here, we investigate the potential effects of long-term human stem cell treatment on kidney function and the gene
Externí odkaz:
https://doaj.org/article/5a8ea6ff5f704486b635bfca0011302c
Autor:
Karin Scharffetter-Kochanek, Christoph Ganss, Matthias Goebeler, Natasha Y. Frank, Korinna Kraft, Dennis P. Orgill, Kathrin Dieter, Katrin Rak, Markus H. Frank, Petra Hagenbusch, Samar Sadeghi, Philipp Schrüfer, George F. Murphy, Ana Maria Waaga-Gasser, Andreas Kerstan, Jasmina Esterlechner, Sabrina Endres, Elke Niebergall-Roth, Mark A. Kluth, Seda Ballikaya, Nicole Stemler, Martin Gasser, Nils Tappenbeck, Hannes M. Schröder
Publikováno v:
Cytotherapy
Background aim Mesenchymal stromal cells (MSCs) hold promise for the treatment of tissue damage and injury. However, MSCs comprise multiple subpopulations with diverse properties, which could explain inconsistent therapeutic outcomes seen among thera
Autor:
Charlotte von Engelhardt, Christoph Ganss, Martin Gasser, Korinna Kraft, Christiane Pfeiffer, Kathrin Dieter, Matthias Goebeler, Markus Stücker, Samar Sadeghi, Markus H. Frank, Mark A. Kluth, George F. Murphy, Cornelia Erfurt-Berge, Ann-Kathrin Dachtler, Natasha Y. Frank, Dennis P. Orgill, Georg Daeschlein, Andreas Kerstan, Tobias Görge, Hannes M. Schröder, Elke Niebergall-Roth, Karin Scharffetter-Kochanek, Michael Jünger, Andreas Klare, Ulrich Meyer-Pannwitt, Seda Ballikaya, Ana Maria Waaga-Gasser, Jasmina Esterlechner
Publikováno v:
JID Innovations, Vol 2, Iss 1, Pp 100067-(2022)
A significant number of chronic venous ulcers (CVUs) fail to heal despite guideline-conform standards of care. Skin-derived ABCB5+ mesenchymal stem cells can dampen the sustained IL-1β‒driven inflammation present in chronic wounds. On the basis of
Autor:
Andreas, Kerstan, Kathrin, Dieter, Elke, Niebergall-Roth, Ann-Kathrin, Dachtler, Korinna, Kraft, Markus, Stücker, Georg, Daeschlein, Michael, Jünger, Tobias, Görge, Ulrich, Meyer-Pannwitt, Cornelia, Erfurt-Berge, Charlotte, von Engelhardt, Andreas, Klare, Christiane, Pfeiffer, Jasmina, Esterlechner, Hannes M, Schröder, Martin, Gasser, Ana M, Waaga-Gasser, Matthias, Goebeler, Seda, Ballikaya, Samar, Sadeghi, George F, Murphy, Dennis P, Orgill, Natasha Y, Frank, Christoph, Ganss, Karin, Scharffetter-Kochanek, Markus H, Frank, Mark A, Kluth
Publikováno v:
JID Innov
A significant number of chronic venous ulcers (CVUs) fail to heal despite of guideline-conform standard of care. Skin-derived ABCB5(+) mesenchymal stem cells (MSCs) can dampen the sustained IL-1β-driven inflammation present in chronic wounds. Based
Autor:
Christoph Ganss, Seda Ballikaya, James Chodosh, Kathrin Dieter, Markus H. Frank, Patrick R Merz, Gerd U. Auffarth, Alexandra Norrick, Natasha Y. Frank, Jasmina Esterlechner, Mark A. Kluth, Nicole Stemler, Samar Sadeghi, Elke Niebergall-Roth, Saadettin Sel, Bruce R. Ksander, Ann-Kathrin Dachtler, Claus Cursiefen, Ulf Dehio, Hannes M. Schröder
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-21 (2021)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background While therapeutic success of the limbal tissue or cell transplantation to treat severe cases of limbal stem cell (LSC) deficiency (LSCD) strongly depends on the percentage of LSCs within the transplanted cells, prospective LSC enrichment h