Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Samar K. Lowalekar"'
Publikováno v:
American Journal of Transplantation. 14:2253-2262
Organ preservation at 4°C results in temporally irreversible injury to cellular structure and function. This study was designed to evaluate the possibility of storing hearts at ambient temperatures in novel organ preservation solution Somah to preve
Autor:
Subbarao V. Yalla, Maryrose P. Sullivan, Samar K. Lowalekar, Vivian Cristofaro, Ziv Radisavljevic
Publikováno v:
Neurourology and Urodynamics. 31:586-592
Aims Caveolae are specialized regions of the cell membrane that modulate signal transduction and alterations in these structures affect bladder smooth muscle (BSM) contraction. Since bladder dysfunctions are common in the elderly, we evaluated the ef
Publikováno v:
Journal of Cardiothoracic Surgery
Objectives Hearts preserved ex vivo at 4°C undergo time-dependent irreversible injury due to extreme hypothermia. Studies using novel organ preservative solution SOMAH, suggest that hearts are optimally `preserved' at subnormothermic temperature of
Publikováno v:
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 33(9)
Hearts preserved ex vivo at extreme hypothermia (4°C) undergo time-dependent irreversible injury. Our studies using a novel solution, Somah, suggest that hearts are viably preserved at 21°C. In this study we evaluate the relative efficacy of Somah
Publikováno v:
Transplantation proceedings. 45(9)
Objective To identify and evaluate the ideal temperature for long-term storage of hearts from donation after cardiocirculatory death, in the novel organ preservation solution Somah. Methods DCD hearts from Sprague-Dawley rats were harvested after 30
Autor:
Samar K. Lowalekar, Haiyan Cao, Patrick R. Treanor, Hemant S. Thatte, Charles K. Allam, Xiu-Gui Lu, Vladimir Birjiniuk, Kay B Leissner
Publikováno v:
Journal of Anesthesia & Clinical Research.
Background: Even after several years of study, the intra-operative diagnosis of Malignant Hyperthermia (MH) and the approach to anesthesia in MH-susceptible individuals has remained a challenge. In this study we present the pre-operative and intra-op
Autor:
Samar K, Lowalekar, Vivian, Cristofaro, Ziv M, Radisavljevic, Subbarao V, Yalla, Maryrose P, Sullivan
Publikováno v:
Neurourology and urodynamics. 31(4)
Caveolae are specialized regions of the cell membrane that modulate signal transduction and alterations in these structures affect bladder smooth muscle (BSM) contraction. Since bladder dysfunctions are common in the elderly, we evaluated the effect
Publikováno v:
Journal of Urology. 185
lowed by reoxygenation with 21% oxygen for one hour; cycling in this manner for 48 hours. After 48 hours, samples were collected and processed for fluorometric and enzyme immunoassay of cell injury and transmission electron microscopy. RESULTS: Lipid
Publikováno v:
The Journal of Heart and Lung Transplantation. 33:S176
Publikováno v:
The Journal of Heart and Lung Transplantation. 33:S120
Purpose: Hearts procured for transplantation and preserved at extreme hypothermia (4°C), undergo time-dependent irreversible injury. Our studies using a rationally designed Somah solution, suggest that hearts can be preserved in robustly viable stat