Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Samar Bel Hadj"'
Autor:
Alexandre Sze, David Olagnier, Samar Bel Hadj, Xiaoying Han, Xiao Hong Tian, Hong-Tao Xu, Long Yang, Qingwen Shi, Penghua Wang, Mark A. Wainberg, Jian Hui Wu, Rongtuan Lin
Publikováno v:
Viruses, Vol 9, Iss 10, p 287 (2017)
Flaviviruses including Zika, Dengue and Hepatitis C virus cause debilitating diseases in humans, and the former are emerging as global health concerns with no antiviral treatments. We investigated Sophora Flavecens, used in Chinese medicine, as a sou
Externí odkaz:
https://doaj.org/article/906732291e9c425988c75bbc0a34e75f
Autor:
David Olagnier, Alexandre Sze, Samar Bel Hadj, Cindy Chiang, Courtney Steel, Xiaoying Han, Jean-Pierre Routy, Rongtuan Lin, John Hiscott, Julien van Grevenynghe
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004575 (2014)
The mechanisms involved in the persistence of activated CD4+ T lymphocytes following primary human T leukemia/lymphoma virus type 1 (HTLV-1) infection remain unclear. Here, we demonstrate that the HTLV-1 Tax oncoprotein modulates phosphorylation and
Externí odkaz:
https://doaj.org/article/dbc7aea3169c4e23b8f97b7b628bf276
Autor:
Christine Vande Velde, Karli K McDonald, Yasmin Boukhedimi, Melissa McAlonis-Downes, Christian S Lobsiger, Samar Bel Hadj, Andre Zandona, Jean-Pierre Julien, Sameer B Shah, Don W Cleveland
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22031 (2011)
Mutations in superoxide dismutase (SOD1) are causative for inherited amyotrophic lateral sclerosis. A proportion of SOD1 mutant protein is misfolded onto the cytoplasmic face of mitochondria in one or more spinal cord cell types. By construction of m
Externí odkaz:
https://doaj.org/article/14f4e00cf1e547a98d384acdc5447147
Autor:
Volkan Seyrantepe, Pablo Lema, Aurore Caqueret, Larbi Dridi, Samar Bel Hadj, Stephane Carpentier, Francine Boucher, Thierry Levade, Lionel Carmant, Roy A Gravel, Edith Hamel, Pascal Vachon, Graziella Di Cristo, Jacques L Michaud, Carlos R Morales, Alexey V Pshezhetsky
Publikováno v:
PLoS Genetics, Vol 6, Iss 9, p e1001118 (2010)
Tay-Sachs disease is a severe lysosomal disorder caused by mutations in the HexA gene coding for the α-subunit of lysosomal β-hexosaminidase A, which converts G(M2) to G(M3) ganglioside. Hexa(-/-) mice, depleted of β-hexosaminidase A, remain asymp
Externí odkaz:
https://doaj.org/article/f14d9d3eff9a44e1970e7c4d0678171e
Autor:
Yiliu Liu, Samar Bel Hadj, Alexandre Sze, Marie-Line Goulet, Rassin R. Lababidi, Sidi Mehdi Belgnaoui, Rongtuan Lin, Jörg H. Fritz, Chunfu Zheng, David Olagnier
Publikováno v:
Journal of Virology
STING has emerged in recent years as a key player in orchestrating innate immune responses to cytosolic DNA and RNA derived from pathogens. However, the regulation of STING still remains poorly defined. In the present study, we investigated the mecha
Autor:
Angelino Calderone, Samar Bel-Hadj, Robert Clement, Jessica Drapeau, Louis Villeneuve, Hugues Gosselin, Viviane El-Helou
Publikováno v:
Journal of Cellular Physiology. 207:165-173
The present study examined whether natriuretic peptide expression in the scar of post-myocardial infarcted (MI) rats was derived at least in part by residing myofibroblasts. ANP and BNP mRNA levels were significantly increased in the non-infarcted le
Autor:
Jian Hui Wu, Penghua Wang, Hongtao Xu, Long Yang, Samar Bel Hadj, David Olagnier, Xiaoying Han, Alexandre Sze, Mark A. Wainberg, Rongtuan Lin, Qingwen Shi, Xiao Hong Tian
Publikováno v:
Viruses, Vol 9, Iss 10, p 287 (2017)
Viruses
Viruses
Flaviviruses including Zika, Dengue and Hepatitis C virus cause debilitating diseases in humans, and the former are emerging as global health concerns with no antiviral treatments. We investigated Sophora Flavecens, used in Chinese medicine, as a sou
Autor:
Samar Bel-Hadj, Jessica Drapeau, Hugues Gosselin, Viviane El-Helou, Robert Clement, Angelino Calderone
Publikováno v:
Nitric oxide : biology and chemistry. 14(4)
The antiproliferative action of nitric oxide (NO) has been well established and increased production was reported in the infarcted rat heart. Concomitantly, increased DNA synthesis and hyperplasia of cardiac myocytes were documented in the hypertroph
Autor:
Robert Clement, Hugues Gosselin, Jessica Drapeau, Louis-Eric Trudeau, Angelino Calderone, Louis Villeneuve, Samar Bel-Hadj, Viviane El-Helou
Publikováno v:
Journal of cellular physiology. 204(1)
Nerve fiber innervation of the scar following myocardial damage may have occurred either via the growth of pre-existing fibers and/or the mobilization of neural stem cells. The present study examined whether neural stem cells were recruited to the in
Autor:
Samar Bel Hadj, Jean-Pierre Routy, Rongtuan Lin, Julien van Grevenynghe, David Olagnier, Courtney Steel, John Hiscott, Cindy Chiang, Xiaoying Han, Alexandre Sze
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004575 (2014)
PLoS Pathogens
PLoS Pathogens
The mechanisms involved in the persistence of activated CD4+ T lymphocytes following primary human T leukemia/lymphoma virus type 1 (HTLV-1) infection remain unclear. Here, we demonstrate that the HTLV-1 Tax oncoprotein modulates phosphorylation and