Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Samar A. Hegazy"'
Autor:
Bryan Donnelly, Samar A Hegazy, Nallasivam Palanisamy, Zhaoyong Feng, Tarek A. Bismar, Bruce J. Trock, Darryl Yu
Publikováno v:
Journal of cancer research and clinical oncology. 144(11)
To assess the prognostic value of ERG and PTEN protein expression as two of the most common genetic aberration in men with prostate cancer managed non-surgically by androgen deprivation therapy (ADT). 463 tumor samples were assessed by double immunoh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13db8c0b8d222d70a3e7246096299f62
https://pubmed.ncbi.nlm.nih.gov/30101374
https://pubmed.ncbi.nlm.nih.gov/30101374
Autor:
Tarek A. Bismar, Mohammed Alshalalfa, Michael Dolph, Bryan Donnelly, Samar A Hegazy, Kuo-Cheng Huang
Publikováno v:
Cancer Biology & Therapy. 15:1120-1128
ERG and androgen receptor (AR) are known to function cooperatively in prostate cancer (PCa) progression. However, the prognostic value of combined ERG and AR expression and potential pathways are not well characterized. We assessed ERG and AR protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c12a02b387240d7909a546a8dd70a20c
https://doi.org/10.4161/cbt.29689
https://doi.org/10.4161/cbt.29689
Autor:
Jonathan Penner-Chea, Michael Weinfeld, Todd R. Mereniuk, Robert A. Maranchuk, Gary K. Freschauf, Anja Schindler, Samar A. Hegazy, Raymond Lai, Edan Foley
Publikováno v:
Cancer Research. 72:5934-5944
A genetic screen using a library of 6,961 siRNAs led to the identification of SHP-1 (PTPN6), a tumor suppressor frequently mutated in malignant lymphomas, leukemias, and prostate cancer, as a potential synthetic lethal partner of the DNA repair prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6088bb2f7947d3d914ad7f6eb44f1b9
https://doi.org/10.1158/0008-5472.can-12-0939
https://doi.org/10.1158/0008-5472.can-12-0939
Autor:
Benjamin Adam, Raymond Lai, Susan E. Andrew, Samar A. Hegazy, Fang Wu, Pascal Gelebart, Leah C. Young, Kathleen M. Bone, Jelena L. Holovati, Peng Wang, Liang Li
Publikováno v:
The American Journal of Pathology. 179:411-421
The fusion tyrosine kinase NPM-ALK is central to the pathogenesis of ALK-positive anaplastic large cell lymphoma (ALK+ALCL). We recently identified that MSH2, a key DNA mismatch repair (MMR) protein integral to the suppression of tumorigenesis, is an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44136d8e0113f457fd689934d2cd4576
https://doi.org/10.1016/j.ajpath.2011.03.045
https://doi.org/10.1016/j.ajpath.2011.03.045
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 37(9)
Alpha-methylacyl-CoA racemase (AMACR) is a well-characterized marker extensively utilized in prostate cancer (PCA) diagnosis. However, the prognostic value of AMACR expression and its relation to TMPRSS2-ERG gene rearrangement as one of the most comm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771901fde5e22253c38161800ecf51fc
https://pubmed.ncbi.nlm.nih.gov/27271990
https://pubmed.ncbi.nlm.nih.gov/27271990
Autor:
Mohammed Alshalalfa, Samar A Hegazy, John D. Lewis, Bryan Donnelly, Konstantin Stoletov, Tarek A. Bismar, Hatem Abou-Ouf, Tingting Wang
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 94(12)
Ankyrin G (ANK3) is a member of the Ankyrin family, which functions to provide cellular stability by anchoring the cytoskeleton to the plasma membrane. Deregulation of ANK3 expression has been observed in multiple human cancers but its mechanism rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29e419fb40b5e20f750cac1954bd5b5
https://pubmed.ncbi.nlm.nih.gov/27534968
https://pubmed.ncbi.nlm.nih.gov/27534968
Autor:
Karl Riabowol, Tarek A. Bismar, Arash Nabbi, Asma Salman, Mohammed Alshalalfa, Amal Almami, Samar A Hegazy, Hatem Abou-Ouf
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 37(7)
The inhibitor of growth family member 3 (ING3) is a member of the ING tumor suppressor family. Although its expression has been reported in various types of cancers, the role of ING3 and its prognostic value in prostate cancer (PCa) has not been inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd66790781f8bbca3fab67412da6f897
https://pubmed.ncbi.nlm.nih.gov/26803516
https://pubmed.ncbi.nlm.nih.gov/26803516
Autor:
Mohammed Alshalalfa, Ashraf Bakkar, Reda Alhajj, Hatem Abou-Ouf, Moulay A. Alaoui-Jamali, Samar A Hegazy, Felix Y. Feng, Krikor Bijian, Amal Almami, L. Petersen, Tarek A. Bismar
Publikováno v:
Molecular biology reports. 43(4)
MicroRNAs (miRNAs) are small non-coding RNAs that function in transcriptional and post-transcriptional regulation of gene expression. Several miRNAs have been implicated in regulating prostate cancer (PCa) progression. Deregulations of miRNA regulato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49af2c91c464b086f6c6310650281b58
https://pubmed.ncbi.nlm.nih.gov/26907180
https://pubmed.ncbi.nlm.nih.gov/26907180
Autor:
Pascal Gelebart, Robert J. Ingham, Mona Anand, Abdulraheem Alshareef, Raymond Lai, Hanan Armanious, Samar A. Hegazy
Publikováno v:
Cellular signalling. 25(1)
Our previous oligonucleotide array studies revealed that ALK-positive anaplastic large cell lymphoma (ALK + ALCL) express high levels of the disheveled proteins (Dvls), a family of proteins that is integral to the Wnt signaling pathways. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5a16fa679b2f633e0c881f2dc02742
https://pubmed.ncbi.nlm.nih.gov/23022960
https://pubmed.ncbi.nlm.nih.gov/23022960
Autor:
Jianchang Yang, Pascal Gélébart, David Sharon, Xiaoxia Ye, Todd P. W. McMullen, Raymond Lai, Fang Wu, Yupo Ma, Samar A. Hegazy, Peng Wang, Jingdong Zhang, Mary M. Hitt
Publikováno v:
Cellular signalling. 24(10)
SALL4 is one of the master transcriptional factors that are crucial in maintaining the pluripotency of embryonic stem cells (ESCs). While the expression of SALL4 is normally restricted to ESCs and somatic stem cells, we found that it is aberrantly ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689d4615ece469c30c8f23eec8eeb353
https://pubmed.ncbi.nlm.nih.gov/22743134
https://pubmed.ncbi.nlm.nih.gov/22743134