Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Samar A. El-Kalyoubi"'
Autor:
Samar A. El-Kalyoubi, Hesham A. M. Gomaa, Elshimaa M. N. Abdelhafez, Mohamed Ramadan, Fatimah Agili, Bahaa G. M. Youssif
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 716 (2023)
The investigation of novel EGFR and BRAFV600E dual inhibitors is intended to serve as targeted cancer treatment. Two sets of purine/pteridine-based derivatives were designed and synthesized as EGFR/BRAFV600E dual inhibitors. The majority of the compo
Externí odkaz:
https://doaj.org/article/04089e050b4e41e8bbe9bf17f6281d12
Autor:
Samar A. El-Kalyoubi, Ehab S. Taher, Tarek S. Ibrahim, Mohammed Farrag El-Behairy, Amany M. M. Al-Mahmoudy
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 494 (2022)
A series of quinoline–uracil hybrids (10a–l) has been rationalized and synthesized. The inhibitory activity against hCA isoforms I, II, IX, and XII was explored. Compounds 10a–l demonstrated powerful inhibitory activity against all tested hCA i
Externí odkaz:
https://doaj.org/article/ba1011e7b67d4fe2bed1d304b66199bf
Autor:
Samar A. El-Kalyoubi, Ahmed Ragab, Ola A. Abu Ali, Yousry A. Ammar, Mohamed G. Seadawy, Aya Ahmed, Eman A. Fayed
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 376 (2022)
The first outbreak in Wuhan, China, in December 2019 was reported about severe acute coronaviral syndrome 2 (SARS-CoV-2). The global coronavirus disease 2019 (COVID-19) pandemic in 2020 resulted in an extremely high potential for dissemination. No dr
Externí odkaz:
https://doaj.org/article/a8e622a3d6b740f1a5df2c63bb63927a
Autor:
Samar A. El-Kalyoubi
Publikováno v:
Chemistry Central Journal, Vol 12, Iss 1, Pp 1-14 (2018)
Abstract Background Described a series of main target compounds pyrimido[5,4-e][1,2,4]triazines is obtained via condensation of 6-hydrazinyluracil with different aromatic aldehydes to give the hydrazones followed by nitrosation with HNO2 then intramo
Externí odkaz:
https://doaj.org/article/03098a21b27c49ec8a77cc0e88ef2e38
Publikováno v:
Chemistry Central Journal, Vol 11, Iss 1, Pp 1-13 (2017)
Abstract Background Uracil derivatives have a great attraction because they play an important role in pharmacological activities. Pyrimidodiazepines, lumazines, triazolopyrimidines and xanthines have significant wide spectrum activities including ant
Externí odkaz:
https://doaj.org/article/1cca9221825746db900c784fd1585e40
Publikováno v:
Chemistry Central Journal, Vol 11, Iss 1, Pp 1-1 (2017)
Externí odkaz:
https://doaj.org/article/5d59c8f1bb76490a9fe621d14e3ed72f
Publikováno v:
Molecular Diversity. 26:341-363
Several coumarin-containing substitute nitrogen heterocycles have recently received considerable importance due to their diverse pharmacological properties. One-pot and rapid synthesis of coumarin derivatives was achieved via reactions of acetyl-coum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adac1214c3c054e36ea746bde88be8c6
https://doi.org/10.1007/s11030-021-10224-4
https://doi.org/10.1007/s11030-021-10224-4
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 20
International Journal of Molecular Sciences, Vol 22, Iss 10979, p 10979 (2021)
Volume 22
Issue 20
International Journal of Molecular Sciences, Vol 22, Iss 10979, p 10979 (2021)
Novel xanthine and imidazolone derivatives were synthesized based on oxazolone derivatives 2a-c as a key intermediate. The corresponding xanthine 3-5 and imidazolone derivatives 6-13 were obtained via reaction of oxazolone derivative 2a-c with 5,6-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40889c0ddc3e1341a77c4729e51860a2
Publikováno v:
Molecular diversity. 26(1)
Several coumarin-containing substitute nitrogen heterocycles have recently received considerable importance due to their diverse pharmacological properties. One-pot and rapid synthesis of coumarin derivatives was achieved via reactions of acetyl-coum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c7b79fced6ab039f7dbea63dbacf37f6
https://pubmed.ncbi.nlm.nih.gov/33895960
https://pubmed.ncbi.nlm.nih.gov/33895960
Autor:
Fatimah Agili, Samar A. El-Kalyoubi
Publikováno v:
Molecules
Volume 25
Issue 21
Molecules, Vol 25, Iss 5205, p 5205 (2020)
Volume 25
Issue 21
Molecules, Vol 25, Iss 5205, p 5205 (2020)
Ethyl 5-arylpyridopyrimidine-6-carboxylates 3a&ndash
d were prepared as a one pot three component reaction via the condensation of different aromatic aldehydes and ethyl acetoacetate with 6-amino-1-benzyluracil 1a under reflux condition in ethan
d were prepared as a one pot three component reaction via the condensation of different aromatic aldehydes and ethyl acetoacetate with 6-amino-1-benzyluracil 1a under reflux condition in ethan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bfad2dd68922bd63e249ef19327ada2