Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Samanthe M. Lyons"'
Autor:
Samanthe M. Lyons, Elaheh Alizadeh, Joshua Mannheimer, Katherine Schuamberg, Jordan Castle, Bryce Schroder, Philip Turk, Douglas Thamm, Ashok Prasad
Publikováno v:
Biology Open, Vol 5, Iss 3, Pp 289-299 (2016)
Metastatic cancer cells for many cancers are known to have altered cytoskeletal properties, in particular to be more deformable and contractile. Consequently, shape characteristics of more metastatic cancer cells may be expected to have diverged from
Externí odkaz:
https://doaj.org/article/3f4449276a1b4eb093dca64289324d33
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 3, p e1003533 (2014)
Biological protein interactions networks such as signal transduction or gene transcription networks are often treated as modular, allowing motifs to be analyzed in isolation from the rest of the network. Modularity is also a key assumption in synthet
Externí odkaz:
https://doaj.org/article/553271851ff44765b4f6312fbedb666c
Autor:
Samanthe M Lyons, Ashok Prasad
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34488 (2012)
In mammalian and bacterial cells simple phosphorylation circuits play an important role in signaling. Bacteria have hundreds of two-component signaling systems that involve phosphotransfer between a receptor and a response regulator. In mammalian cel
Externí odkaz:
https://doaj.org/article/1764d89a2b5e453491e156c97573c094
Autor:
Douglas H. Thamm, Ashok Prasad, Jordan Castle, Samanthe M. Lyons, Katherine Schuamberg, Bryce W. Schroder, Philip J. Turk, Elaheh Alizadeh, Joshua Mannheimer
Publikováno v:
Biology Open, Vol 5, Iss 3, Pp 289-299 (2016)
Biology Open
Biology Open
Metastatic cancer cells for many cancers are known to have altered cytoskeletal properties, in particular to be more deformable and contractile. Consequently, shape characteristics of more metastatic cancer cells may be expected to have diverged from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d508a497c37d89febe584990152bdd
https://doi.org/10.1242/bio.013409
https://doi.org/10.1242/bio.013409
Publikováno v:
Integrative Biology. 8:1183-1193
We study the shape characteristics of osteosarcoma cancer cell lines on surfaces of differing hydrophobicity using Zernike moments to represent cell shape. We compare the shape characteristics of four invasive cell lines with a corresponding less-inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566057d759807ab9e90c68871daa7de2
https://doi.org/10.1039/c6ib00100a
https://doi.org/10.1039/c6ib00100a
Publikováno v:
Biophysical Journal. 112:124a-125a
This work is based on the hypothesis that shape of the cell on substrate is determined by the active mechanical properties of the cytoskeleton. Since invasive cancer cells are believed to have altered mechanical properties compared with non-invasive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac10aee134ad50401c64bb09b2164039
https://doi.org/10.1016/j.bpj.2016.11.695
https://doi.org/10.1016/j.bpj.2016.11.695
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 3, p e1003533 (2014)
PLoS Computational Biology
PLoS Computational Biology
Biological protein interactions networks such as signal transduction or gene transcription networks are often treated as modular, allowing motifs to be analyzed in isolation from the rest of the network. Modularity is also a key assumption in synthet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d448582d5443bf4a923d552017d316fb
http://europepmc.org/articles/PMC3967935?pdf=render
http://europepmc.org/articles/PMC3967935?pdf=render
Autor:
Samanthe M. Lyons, Ashok Prasad
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 4, p e34488 (2012)
PLoS ONE, Vol 7, Iss 4, p e34488 (2012)
In mammalian and bacterial cells simple phosphorylation circuits play an important role in signaling. Bacteria have hundreds of two-component signaling systems that involve phosphotransfer between a receptor and a response regulator. In mammalian cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71968de2a966802773d4eb9d840ab80
Autor:
Jordan Castle, Joshua Mannheimer, Samanthe M. Lyons, Bryce Schroeder, Diego Krapf, Elaheh Alizadeh, David R. Smith, Ashok Prasad, Randy A. Bartels
Publikováno v:
Biophysical Journal. (2):140a
Different types of cells, i.e. from different tissues, typically look quite different from each other. Even when cultured on two-dimensional surfaces like glass slides or tissue culture polystyrene under identical conditions, cells adopt different sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0382ec090d415587019e905cc25f33f
Autor:
Ashok Prasad, Samanthe M. Lyons
Publikováno v:
Biophysical Journal. (2):661a
A traditional view of biological modules is that they operate the same in the presence and absence of downstream targets including gene promoters and other proteins. Recent theoretical work [1] suggests that this may not be the case and the propertie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18844baf5ffe53c2a0ff6c373cc23a21