Impact of meningococcal ACWY conjugate vaccines on pharyngeal carriage in adolescents: evidence for herd protection from the UK MenACWY programme

Autor: Jeremy P. Carr, Jenny M. MacLennan, Emma Plested, Holly B. Bratcher, Odile B. Harrison, Parvinder K. Aley, James E. Bray, Susana Camara, Charlene M.C. Rodrigues, Kimberly Davis, Angela Bartolf, David Baxter, J. Claire Cameron, Richard Cunningham, Saul N. Faust, Katy Fidler, Rohit Gowda, Paul T. Heath, Stephen Hughes, Sujata Khajuria, David Orr, Mala Raman, Andrew Smith, David P.J. Turner, Elizabeth Whittaker, Christopher J. Williams, Christos S. Zipitis, Andrew J. Pollard, Jennifer Oliver, Begonia Morales-Aza, Aiswarya Lekshmi, Stephen A. Clark, Ray Borrow, Hannah Christensen, Caroline Trotter, Adam Finn, Martin C. Maiden, Matthew D. Snape, Keith A. Jolley, Karen Ford, Hannah Roberts, Karen Palmer, Debbie Suggitt, Nicola Pemberton, Samantha Ray, Mandy Wootton, Shamez N. Ladhani, Daniel Owens, Katrina Cathie, Simon Royal, Neil Oldfield, Roisin Ure, Jennifer Richards, Rebecca Ramsay, Samantha Thomson Hill, Kaltun Duale

Publikováno v: Carr, J P, MacLennan, J M, Plested, E, Bratcher, H B, Harrison, O B, Aley, P K, Oliver, J, Morales-Aza, B, Christensen, H & Maiden, M C & et, A 2022, ' Impact of meningococcal ACWY conjugate vaccines on pharyngeal carriage in adolescents : evidence for herd protection from the UK MenACWY programme ', Clinical Microbiology and Infection, vol. 28, no. 12, pp. 1649.e1-1649.e8 . https://doi.org/10.1016/j.cmi.2022.07.004

Objective:Serogroup W and Y invasive meningococcal disease increased globally from 2000 onwards. Responding to a rapid increase in serogroup W clonal complex 11 (W:cc11) invasive meningococcal disease, the UK replaced an adolescent booster dose of me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bce77ca6a0e717154645cbc98f89339
https://researchonline.lshtm.ac.uk/id/eprint/4667094/1/Carr_etal_2022_Impact-of-meningococcal-acwy-conjugate.pdf

Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

Autor: Pedro M Folegatti, Katie J Ewer, Parvinder K Aley, Brian Angus, Stephan Becker, Sandra Belij-Rammerstorfer, Duncan Bellamy, Sagida Bibi, Mustapha Bittaye, Elizabeth A Clutterbuck, Christina Dold, Saul N Faust, Adam Finn, Amy L Flaxman, Bassam Hallis, Paul Heath, Daniel Jenkin, Rajeka Lazarus, Rebecca Makinson, Angela M Minassian, Katrina M Pollock, Maheshi Ramasamy, Hannah Robinson, Matthew Snape, Richard Tarrant, Merryn Voysey, Catherine Green, Alexander D Douglas, Adrian V S Hill, Teresa Lambe, Sarah C Gilbert, Andrew J Pollard, Jeremy Aboagye, Kelly Adams, Aabidah Ali, Elizabeth Allen, Jennifer L. Allison, Rachel Anslow, Edward H. Arbe-Barnes, Gavin Babbage, Kenneth Baillie, Megan Baker, Natalie Baker, Philip Baker, Ioana Baleanu, Juliana Ballaminut, Eleanor Barnes, Jordan Barrett, Louise Bates, Alexander Batten, Kirsten Beadon, Rebecca Beckley, Eleanor Berrie, Lisa Berry, Amy Beveridge, Kevin R. Bewley, Else Margreet Bijker, Tracey Bingham, Luke Blackwell, Caitlin L. Blundell, Emma Bolam, Elena Boland, Nicola Borthwick, Thomas Bower, Amy Boyd, Tanja Brenner, Philip D. Bright, Charlie Brown-O'Sullivan, Emily Brunt, Jamie Burbage, Sharon Burge, Karen R. Buttigieg, Nicholas Byard, Ingrid Cabera Puig, Anna Calvert, Susana Camara, Michelangelo Cao, Federica Cappuccini, Melanie Carr, Miles W. Carroll, Victoria Carter, Katrina Cathie, Ruth J. Challis, Sue Charlton, Irina Chelysheva, Jee-Sun Cho, Paola Cicconi, Liliana Cifuentes, Helen Clark, Elizabeth Clark, Tom Cole, Rachel Colin-Jones, Christopher P. Conlon, Aislinn Cook, Naomi S. Coombes, Rachel Cooper, Catherine A. Cosgrove, Karen Coy, Wendy E.M. Crocker, Christina J. Cunningham, Brad E. Damratoski, Lynne Dando, Mehreen S. Datoo, Hannah Davies, Hans De Graaf, Tesfaye Demissie, Claudio Di Maso, Isabelle Dietrich, Tao Dong, Francesca R. Donnellan, Naomi Douglas, Charlotte Downing, Jonathan Drake, Rachael Drake-Brockman, Ruth Elizabeth Drury, Susanna Jane Dunachie, Nick J. Edwards, Frances D.L. Edwards, Chris J. Edwards, Sean C. Elias, Michael J. Elmore, Katherine R.W. Emary, Marcus Rex English, Susanne Fagerbrink, Sally Felle, Shuo Feng, Samantha Field, Carine Fixmer, Clare Fletcher, Karen J. Ford, Jamie Fowler, Polly Fox, Emma Francis, John Frater, Julie Furze, Michelle Fuskova, Eva Galiza, Diane Gbesemete, Ciaran Gilbride, Kerry Godwin, Giacomo Gorini, Lyndsey Goulston, Caroline Grabau, Lara Gracie, Zoe Gray, Lucy Belle Guthrie, Mark Hackett, Sandro Halwe, Elizabeth Hamilton, Joseph Hamlyn, Brama Hanumunthadu, Irasha Harding, Stephanie A. Harris, Andrew Harris, Daisy Harrison, Clare Harrison, Thomas C. Hart, Louise Haskell, Sophia Hawkins, Ian Head, John Aaron Henry, Jennifer Hill, Susanne H.C. Hodgson, Mimi M. Hou, Elizabeth Howe, Nicola Howell, Cecilia Hutlin, Sabina Ikram, Catherine Isitt, Poppy Iveson, Susan Jackson, Frederic Jackson, Sir William James, Megan Jenkins, Elizabeth Jones, Kathryn Jones, Christine E. Jones, Bryony Jones, Reshma Kailath, Konstantinos Karampatsas, Jade Keen, Sarah Kelly, Dearbhla Kelly, David Kerr, Simon Kerridge, Liaquat Khan, Uzma Khan, Annabel Killen, Jasmin Kinch, Thomas B. King, Lloyd King, Jade King, Lucy Kingham-Page, Paul Klenerman, Francesca Knapper, Julian C. Knight, Daniel Knott, Stanislava Koleva, Alexandra Kupke, Colin W. Larkworthy, Jessica P.J. Larwood, Anna Laskey, Alison M. Lawrie, Arlene Lee, Kim Yee Ngan Lee, Emily A Lees, Helen Legge, Alice Lelliott, Nana-Marie Lemm, Amelia M. Lias, Aline Linder, Samuel Lipworth, Xinxue Liu, Shuchang Liu, Raquel Lopez Ramon, May Lwin, Francesca Mabesa, Meera Madhavan, Garry Mallett, Kushal Mansatta, Ines Marcal, Spyridoula Marinou, Emma Marlow, Julia L. Marshall, Jane Martin, Joanne McEwan, Lorna McInroy, Gretchen Meddaugh, Alexander J. Mentzer, Neginsadat Mirtorabi, Maria Moore, Edward Moran, Ella Morey, Victoria Morgan, Susan Jane Morris, Hazel Morrison, Gertraud Morshead, Richard Morter, Yama F. Mujadidi, Jilly Muller, Tatiana Munera-Huertas, Claire Munro, Alasdair Munro, Sarah Murphy, Vincent J. Munster, Philomena Mweu, Andrés Noé, Fay L. Nugent, Elizabeth Nuthall, Katie O'Brien, Daniel O'Connor, Blanché Oguti, Jennifer L. Oliver, Catarina Oliveira, Peter John O'Reilly, Mairead Osborn, Piper Osborne, Cathy Owen, Daniel Owens, Nelly Owino, Mihaela Pacurar, Kaye Parker, Helena Parracho, Maia Patrick-Smith, Victoria Payne, Jennifer Pearce, Yanchun Peng, Marco Polo Peralta Alvarez, James Perring, Katja Pfafferott, Dimitra Pipini, Emma Plested, Helen Pluess-Hall, Katrina Pollock, Ian Poulton, Laura Presland, Samuel Provstgaard-Morys, David Pulido, Kajal Radia, Fernando Ramos Lopez, Jade Rand, Helen Ratcliffe, Thomas Rawlinson, Sarah Rhead, Amy Riddell, Adam John Ritchie, Hannah Roberts, Joanna Robson, Sophie Roche, Cornelius Rohde, Christine S. Rollier, Rossana Romani, Indra Rudiansyah, Stephen Saich, Sara Sajjad, Stephannie Salvador, Lidia Sanchez Riera, Helen Sanders, Katherine Sanders, Shari Sapaun, Chloe Sayce, Ella Schofield, Gavin Screaton, Beatrice Selby, Calum Semple, Hannah R. Sharpe, Imam Shaik, Adam Shea, Holly Shelton, Sarah Silk, Laura Silva-Reyes, Donal T. Skelly, Heather Smee, Catherine C. Smith, David J. Smith, Rinn Song, Alexandra J. Spencer, Elizabeth Stafford, Amy Steele, Elena Stefanova, Lisa Stockdale, Anna Szigeti, Abdessamad Tahiri-Alaoui, Moira Tait, Helen Talbot, Rachel Tanner, Iona Jennifer Taylor, Victoria Taylor, Rebecca Te Water Naude, Nazia Thakur, Yrene Themistocleous, Andreas Themistocleous, Merin Thomas, Tonia M. Thomas, Amber Thompson, Samantha Thomson-Hill, Jennifer Tomlins, Susan Tonks, James Towner, Nguyen Tran, Julia A. Tree, Adam Truby, Kate Turkentine, Cheryl Turner, Nicola Turner, Sally Turner, Toby Tuthill, Marta Ulaszewska, Rachel Varughese, Neeltje Van Doremalen, Kristin Veighey, Marije K. Verheul, Iason Vichos, Elia Vitale, Laura Walker, Marion E.E. Watson, Benjamin Welham, Julie Wheat, Caroline White, Rachel White, Andrew T. Worth, Danny Wright, Suzie Wright, Xin Li Yao, Yasmine Yau

Publikováno v: Lancet (London, England)
The Lancet
Folegatti, P M, Ewer, K J, Aley, P K, Angus, B, Becker, S, Belij-Rammerstorfer, S, Bellamy, D, Bibi, S, Bittaye, M, Clutterbuck, E A, Dold, C, Faust, S N, Finn, A, Flaxman, A L, Hallis, B, Heath, P, Jenkin, D, Lazarus, R, Makinson, R, Minassian, A M, Pollock, K M, Ramasamy, M, Robinson, H, Snape, M, Tarrant, R, Voysey, M, Green, C, Douglas, A D, Hill, A V S, Lambe, T, Gilbert, S C, Pollard, A J 2020, ' Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2 : a preliminary report of a phase 1/2, single-blind, randomised controlled trial ', Lancet . https://doi.org/10.1016/S0140-6736(20)31604-4

Background: The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might be curtailed by vaccination. We assessed the safety, reactogenicity, and immunogenicity of a viral vectored coronavirus vaccine that expresses the spike pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d16eb2fce5a49812715f001501c3dfc
https://eprints.soton.ac.uk/443225/

Psicología y filosofía del humor

Autor: Sixto J. Castro, José Juan Uriarte Uriarte, Gonzalo Martínez Zelaya, Rebeca Puche Navarro, Juan Horacio de Freitas, Félix Caballero Wangüemert, Mónica Romero Sánchez, Darío Páez Rovira, Catalina Argüello Gutiérrez, Pablo Malo Ocejo, Samantha Thomson, Manuel Guerrero-Martelo, Mónica Roncancio Moreno, Pablo García Arias, Esteban de Jesús Rodríguez Migueles, Liane Gabora, Julio César Ossa, Juan Medrano Albéniz, Kirsty Kitto, Andrés Fernando Mendiburo Seguel, Jacqueline Benavides Delgado

El humor se considera un concepto universal, pero, a su vez, relativo a cada cultura. Desde las teorias filosoficas y psicologicas, este se entiende como el producto de una incongruencia, pero tambien como el reflejo de los deseos inconsciente o de l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f004e031967f4b2325d686c2a710204
https://doi.org/10.16925/9789587600865

Su2043 – A Novel Canine Intestinal Organoid Model to Characterize Dose-Exposure-Response of Chemotherapeutic Drugs

Autor: Samantha Thomson, David J. Borts, Todd Atherly, Yoko M. Ambrosini, Dana C. Borcherding, Jonathan P. Mochel, L. W. Wulf, Karin Allenspach, Albert E. Jergens

Publikováno v: Gastroenterology. 156:S-696

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc6ed06fdbc336a3fbd273c677faecf2
https://doi.org/10.1016/s0016-5085(19)38665-2

Inhibitors of phosphopantetheine adenylyltransferase

Autor: Paul D. Tyler, Samantha Thomson, Ann Lewendon, John Barker, Lihua Zhao, William Ure Primrose, Nigel M. Allanson, John K.F. Maclean

Publikováno v: European Journal of Medicinal Chemistry. 38:345-349

Phosphopantetheine adenylyltransferase (PPAT) is an essential enzyme in Coenzyme A biosynthesis. Because bacterial PPAT and mammalian PPAT are dissimilar, this enzyme is an attractive antibacterial target. Based on the structure of the substrate, 4-p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be8cd7f19d8d0b210eb210073b88051
https://doi.org/10.1016/s0223-5234(03)00047-3