Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Samantha Sokup"'
Autor:
Huili Zhai, Stefano Crotti, Alberto Nilo, Barbara Brogioni, Martin Allan, Daniela Proietti, Qi-Ying Hu, Immaculada Margarit, Samantha Sokup, Francesco Berti, Roberto Adamo, Vittorio Cattaneo
Publikováno v:
Bioconjugate Chemistry. 25:2105-2111
We have demonstrated that the insertion of alkyne-containing bifunctional linkers into the tyrosine residues of the carrier protein, followed by the copper mediated azide-alkyne [3 + 2] cycloaddition of carbohydrates, is a robust approach for the pre
Autor:
Michael D. Connolly, Matthew J. LaMarche, Lawrence G. Hamann, Ayako Honda, Brigitte Wiedmann, Subramanian Karur, Shawn D. Britt, Markus Dobler, Rajeshri Ganesh Karki, Prakash Raman, Anup Patnaik, Samantha Sokup, Erin P. Keaney
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:3714-3718
Synthesis and SAR of 2-alkyloxazoles as class III phosphatidylinositol-4-kinase beta (PI4KIIIβ) inhibitors is described. These compounds demonstrate that inhibition of PI4KIIIβ leads to potent inhibition of HCV replication as observed in genotype (