Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Samantha Schmaul"'
Autor:
Maria Protopapa, Samantha Schmaul, Muriel Schraad, Katrin Pape, Frauke Zipp, Stefan Bittner, Timo Uphaus
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Interferon-beta (IFN-β) still plays a fundamental role in immunomodulation of people with multiple sclerosis (MS) with low disease activity and in clinically isolated syndrome (CIS). In 2014, pegylated (PEG) interferon was licensed by th
Externí odkaz:
https://doaj.org/article/7c55d8c9503f468a85eaccaab0749d20
Autor:
Julia Loos, Samantha Schmaul, Theresa Marie Noll, Magdalena Paterka, Miriam Schillner, Julian T. Löffel, Frauke Zipp, Stefan Bittner
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-12 (2020)
Abstract Background T helper (Th) 17 cells are a highly plastic subset of T cells, which in the context of neuroinflammation, are able to acquire pathogenic features originally attributed to Th1 cells (resulting in so called ex-Th17 cells). Thus, a s
Externí odkaz:
https://doaj.org/article/0fdaae02fcca4cb589425a631657ac37
Autor:
Nicholas Hanuscheck, Carine Thalman, Micaela Domingues, Samantha Schmaul, Muthuraman Muthuraman, Florian Hetsch, Manuela Ecker, Heiko Endle, Mohammadsaleh Oshaghi, Gianvito Martino, Tanja Kuhlmann, Katarzyna Bozek, Tim van Beers, Stefan Bittner, Jakob von Engelhardt, Johannes Vogt, Christina Francisca Vogelaar, Frauke Zipp
Publikováno v:
Journal of Experimental Medicine. 219
Evidence is emerging that immune responses not only play a part in the central nervous system (CNS) in diseases but may also be relevant for healthy conditions. We discovered a major role for the interleukin-4 (IL-4)/IL-4 receptor alpha (IL-4Rα) sig
Publikováno v:
Biological chemistryReferences. 402(12)
Astrocytes are key regulators of their surroundings by receiving and integrating stimuli from their local microenvironment, thereby regulating glial and neuronal homeostasis. Cumulating evidence supports a plethora of heterogenic astrocyte subpopulat
Autor:
Christina F. Vogelaar, Carlos Maldet, Dirk Luchtman, Erik Ellwardt, Stefan Bittner, Samantha Schmaul
Publikováno v:
European journal of pharmacology. 871
The humanized anti-CD52 antibody alemtuzumab is successfully used in the treatment of multiple sclerosis (MS) and is thought to exert most of its therapeutic action by depletion and repopulation of mainly B and T lymphocytes. Although neuroprotective
Autor:
Gerhard H. Braus, Samantha Schmaul, Kerstin Schmitt, Nadine Smolinski, Verena Hofer-Pretz, Piotr Neumann, Oliver Valerius
Publikováno v:
Molecular and cellular biology. 37(3)
WD40 repeat proteins fold into characteristic β-propeller structures and control signaling circuits during cellular adaptation processes within eukaryotes. The RACK1 protein of Saccharomyces cerevisiae, Asc1p, consists exclusively of a single seven-