Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Samantha S Soldan"'
Autor:
Jayaraju Dheekollu, Andreas Wiedmer, Samantha S Soldan, Leonardo Josué Castro-Muñoz, Christopher Chen, Hsin-Yao Tang, David W Speicher, Paul M Lieberman
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1010478 (2023)
Epstein-Barr virus (EBV) is a ubiquitous human γ-herpesvirus that is causally associated with various malignancies and autoimmune disease. Epstein-Barr Nuclear Antigen 1 (EBNA1) is the viral-encoded DNA binding protein required for viral episome mai
Externí odkaz:
https://doaj.org/article/cc6470b160ed4578aa96e187f78e3906
Autor:
Chenhe Su, Fang Lu, Samantha S Soldan, R Jason Lamontagne, Hsin-Yao Tang, Giorgia Napoletani, Paul J Farrell, Italo Tempera, Andrew V Kossenkov, Paul M Lieberman
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009834 (2021)
Viruses suppress immune recognition through diverse mechanisms. Epstein-Barr Virus (EBV) establishes latent infection in memory B-lymphocytes and B-cell malignancies where it impacts B-cell immune function. We show here that EBV primary infection of
Externí odkaz:
https://doaj.org/article/e99ab24975eb4f72b9594f06305a1932
Autor:
Samantha S Soldan, Chenhe Su, R Jason Lamontagne, Nicholas Grams, Fang Lu, Yue Zhang, James D Gesualdi, Drew M Frase, Lois E Tolvinski, Kayla Martin, Troy E Messick, Jonathan T Fingerut, Ekaterina Koltsova, Andrew Kossenkov, Paul M Lieberman
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009618 (2021)
Subpopulations of B-lymphocytes traffic to different sites and organs to provide diverse and tissue-specific functions. Here, we provide evidence that epigenetic differences confer a neuroinvasive phenotype. An EBV+ B cell lymphoma cell line (M14) wi
Externí odkaz:
https://doaj.org/article/ca86ceaeb46f4cb994e606787636a2cf
Autor:
R Jason Lamontagne, Samantha S Soldan, Chenhe Su, Andreas Wiedmer, Kyoung Jae Won, Fang Lu, Aaron R Goldman, Jayamanna Wickramasinghe, Hsin-Yao Tang, David W Speicher, Louise Showe, Andrew V Kossenkov, Paul M Lieberman
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009208 (2021)
Epstein-Barr virus (EBV) immortalizes resting B-lymphocytes through a highly orchestrated reprogramming of host chromatin structure, transcription and metabolism. Here, we use a multi-omics-based approach to investigate these underlying mechanisms. A
Externí odkaz:
https://doaj.org/article/48776a669bd044a5a1887f85a9a8d95d
Autor:
Nitish Gulve, Chenhe Su, Zhong Deng, Samantha S. Soldan, Olga Vladimirova, Jayamanna Wickramasinghe, Hongwu Zheng, Andrew V. Kossenkov, Paul. M. Lieberman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The tumor suppressor proteins DAXX and ATRX are frequently mutated in cancers with alternative lengthening of telomeres (ALT). This study shows that DAXX-ATRX regulates p53 chromatin accessibility and DNA damage response and that disruption of this p
Externí odkaz:
https://doaj.org/article/d1a7392ad3ef4bfcb01ce66b8039e48c
Autor:
Samantha S. Soldan, Paul M. Lieberman
Publikováno v:
Nature Reviews Microbiology. 21:51-64
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8f7271708d28ed9668a25f89dec306b
https://doi.org/10.1038/s41579-022-00770-5
https://doi.org/10.1038/s41579-022-00770-5
Autor:
Bradley S. Hollidge, Mary-Virginia Salzano, John M. Ibrahim, Jonathan W. Fraser, Valentina Wagner, Nicole E. Leitner, Susan R. Weiss, Friedemann Weber, Francisco González-Scarano, Samantha S. Soldan
Publikováno v:
Viruses; Volume 14; Issue 7; Pages: 1464
La Crosse virus (LACV) is a major cause of pediatric encephalitis and aseptic meningitis in the Midwestern, Mid-Atlantic, and Southern United States, where it is an emerging pathogen. The LACV Gc glycoprotein plays a critical role in the neuropathoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac7c781bd746fbfc8b915787de0cf2d
Autor:
Emma M Anderson, Troy E. Messick, Italo Tempera, Julianna Deakyne, Drew Frase, Samantha S. Soldan, Benjamin E. Gewurz, Yue Zhang, Yin Wang, Lisa B. Caruso, Paul M. Lieberman
Publikováno v:
Gastric Cancer
BACKGROUND AND AIMS. Epstein-Barr Virus (EBV)-associated Gastric Carcinoma (EBVaGC) is the most common EBV-associated cancer and accounts for ~10% of all gastric cancers (GC). Epstein-Barr virus Nuclear Antigen 1 (EBNA1), which is critical for the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7824e874c24262e81301c735284da05d
https://doi.org/10.1007/s10120-021-01193-6
https://doi.org/10.1007/s10120-021-01193-6
Autor:
Jayaraju Dheekollu, Andreas Wiedmer, Samantha S. Soldan, Leonardo Josué Castro Muñoz, Hsin-Yao Tang, David W. Speicher, Paul M. Lieberman
Epstein-Barr virus (EBV) is a ubiquitous human γ-herpesvirus that is causally associated with various malignancies and autoimmune disease. Epstein-Barr Nuclear Antigen 1 (EBNA1) is the viral-encoded DNA binding protein required for viral episome mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d5ed3459de21a7d9cb429163065c031
https://doi.org/10.1101/2022.03.29.486189
https://doi.org/10.1101/2022.03.29.486189
Autor:
Samantha S. Soldan, Paul M. Lieberman
Publikováno v:
Drug Discov Today Dis Models
Epstein-Barr Virus (EBV) is a ubiquitous human herpesvirus that contributes to the etiology of diverse human cancers and auto-immune diseases. EBV establishes a relatively benign, long-term latent infection in over 90 percent of the adult population.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e840a44368f2149729a383f7572c64
https://doi.org/10.1016/j.ddmod.2020.01.001
https://doi.org/10.1016/j.ddmod.2020.01.001