Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Samantha Perez-Miller"'
Autor:
Piao Zhao, Cheng Tang, Yuqin Yang, Zhen Xiao, Samantha Perez-Miller, Heng Zhang, Guoqing Luo, Hao Liu, Yaqi Li, Qingyi Liao, Fan Yang, Hao Dong, Rajesh Khanna, Zhonghua Liu
Publikováno v:
PLoS Biology, Vol 21, Iss 9, p e3002309 (2023)
The proton-activated chloride (PAC) channel plays critical roles in ischemic neuron death, but its activation mechanisms remain elusive. Here, we investigated the gating of PAC channels using its novel bifunctional modulator C77304. C77304 acted as a
Externí odkaz:
https://doaj.org/article/ba3078cd09e54fe1adc6f2c08397fc90
Autor:
Liberty François-Moutal, Samantha Perez-Miller, David D. Scott, Victor G. Miranda, Niloufar Mollasalehi, May Khanna
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Externí odkaz:
https://doaj.org/article/09f448b2987348ad9e221dcce7459549
Autor:
Liberty François-Moutal, Samantha Perez-Miller, David D. Scott, Victor G. Miranda, Niloufar Mollasalehi, May Khanna
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Transactive response DNA binding protein (TDP-43) is a key player in neurodegenerative diseases. In this review, we have gathered and presented structural information on the different regions of TDP-43 with high resolution structures available. A tho
Externí odkaz:
https://doaj.org/article/4bcdef2eb9204ed99c0be8611ebb5bd9
Autor:
Paz Duran, Santiago Loya‐López, Dongzhi Ran, Cheng Tang, Aida Calderon‐Rivera, Kimberly Gomez, Harrison J. Stratton, Sun Huang, Ya‐ming Xu, E. M. Kithsiri Wijeratne, Samantha Perez‐Miller, Zhiming Shan, Song Cai, Anna T. Gabrielsen, Angie Dorame, Kyleigh A. Masterson, Omar Alsbiei, Cynthia L. Madura, Guoqin Luo, Aubin Moutal, John Streicher, Gerald W. Zamponi, A. A. Leslie Gunatilaka, Rajesh Khanna
Publikováno v:
British Journal of Pharmacology. 180:1267-1285
Postoperative pain occurs in as many as 70% of the over 230 million surgeries performed annually worldwide. Postoperative pain management still relies on opioids despite their negative consequences, resulting in a public health crisis. Therefore, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe5b7670296208e2b9fd7273b01a45f
https://doi.org/10.1111/bph.15974
https://doi.org/10.1111/bph.15974
Autor:
Kimberly Gomez, Cheng Tang, Bin Tan, Samantha Perez-Miller, Dongzhi Ran, Santiago Loya, Aida Calderon-Rivera, Harrison J. Stratton, Paz Duran, Kyleigh A. Masterson, Anna T. Gabrielsen, Omar Alsbiei, Angie Dorame, Maria Serafini, Aubin Moutal, Jun Wang, Rajesh Khanna
Publikováno v:
ACS Chemical Neuroscience. 13:2035-2047
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22f2567596c9f46acc8986a9f0bb90c8
https://doi.org/10.1021/acschemneuro.2c00256
https://doi.org/10.1021/acschemneuro.2c00256
Autor:
Ya-ming Xu, E. M. Kithsiri Wijeratne, Aida Calderon-Rivera, Santiago Loya-López, Samantha Perez-Miller, Rajesh Khanna, A. A. Leslie Gunatilaka
Publikováno v:
ACS Omega.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa74c0b9baf366facb4c1a263996bf11
https://doi.org/10.1021/acsomega.3c02302
https://doi.org/10.1021/acsomega.3c02302
Autor:
Harrison J. Stratton, Lisa Boinon, Kimberly Gomez, Laurent Martin, Paz Duran, Dongzhi Ran, Yuan Zhou, Shizhen Luo, Samantha Perez-Miller, Marcel Patek, Mohab M. Ibrahim, Amol Patwardhan, Aubin Moutal, Rajesh Khanna
Publikováno v:
Pain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1982424575139b5459d24fa24737030
https://doi.org/10.1097/j.pain.0000000000002850
https://doi.org/10.1097/j.pain.0000000000002850
Autor:
Kimberly Gomez, Ulises Santiago, Aida Calderon-Rivera, Paz Duran, Santiago Loya-Lopez, Dongzhi Ran, Samantha Perez-Miller, Handoko Handoko, Paramjit S. Arora, Marcel Patek, Tamara D. King, Huijuan Hu, Carlos J. Camacho, Rajesh Khanna
Publikováno v:
The Journal of Pain. 24:32-33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c793f22925f677e1a64c9e45f198894
https://doi.org/10.1016/j.jpain.2023.02.106
https://doi.org/10.1016/j.jpain.2023.02.106
Autor:
Piao Zhao, Cheng Tang, Yuqin Yang, Zhen Xiao, Samantha Perez-Miller, Heng Zhang, Guoqing Luo, Hao Liu, Yaqi Li, Qingyi Liao, Fan Yang, Hao Dong, Rajesh Khanna, Zhonghua Liu
The proton-activated chloride (PAC) channel plays critical roles in ischemic neuron death, but its activation mechanisms remain elusive. Here, we interrogated PAC channel gating using its unique bidirectional modulator C77304 as a pharmacological pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56fee004416ca71dd45e99dbd133d929
https://doi.org/10.1101/2022.10.31.514568
https://doi.org/10.1101/2022.10.31.514568
Autor:
Kimberly Gomez, Ulises Santiago, Paz Duran, Yuan Zhou, Aida Calderon, Santiago Loya-López, Angie Dorame, Aude Chefdeville, Aubin Moutal, Dongzhi Ran, Samantha Perez-Miller, Yi Lu, Xia Liu, Handoko Handoko, Paramjit Arora, Marcel Patek, Carlos J. Camacho, Rajesh Khanna
Background and Purpose Transmembrane Cav2.2 (N-type) voltage-gated calcium channels are genetically and pharmacologically validated pain targets. Clinical block of Cav2.2 (e.g., with Prialt) or indirect modulation (e.g., with gabapentinoids) mitigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bf170c4854b906f770caba490180150
https://doi.org/10.22541/au.166299307.78275508/v1
https://doi.org/10.22541/au.166299307.78275508/v1